PDB entry 6gei

View 6gei on RCSB PDB site
Description: tead4 (216-434);e263a+y429f complexed with yap peptide (60- 100);s94a and myristoate (covalently bound to lys344, not cys367!) at 1.65a (p41212 crystal form); myristoylation was done by adding myr-coa
Deposited on 2018-04-26, released 2018-09-19
The last revision was dated 2018-10-31, with a file datestamp of 2018-10-26.
Experiment type: XRAY
Resolution: 1.65 Å
R-factor: N/A
AEROSPACI score: 0.42 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transcriptional enhancer factor TEF-3
    Species: Homo sapiens [TaxId:9606]
    Gene: TEAD4, RTEF1, TCF13L1, TEF3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15561 (0-218)
      • engineered mutation (47)
      • engineered mutation (213)
  • Chain 'L':
    Compound: Transcriptional coactivator YAP1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P46937 (0-End)
      • engineered mutation (34)
  • Heterogens: MYR, PO4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6geiA (A:)
grsvassklwmlefsafleqqqdpdtynkhlfvhigqsspsysdpylaavdirqiydkfp
ekkgglkdlfergpsnafflvkfwadlntniedegssfygvssqyespenmiitcstkvc
sfgkqvvekveteyaryenghysyrihrsplceyminfihklkhlpekymmnsvlenfti
lqvvtnrdtqetllciayvfevsasehgaqhhifrlvke

    Sequence, based on observed residues (ATOM records):
    >6geiA (A:)
grsvassklwmlefsafleqqqdpdtynkhlfvhigqsspsysdpylaavdirqiydkfp
ekkgglkdlfergpsnafflvkfwadlntngssfygvssqyespenmiitcstkvcsfgk
qvvekveteyaryenghysyrihrsplceyminfihklkhlpekymmnsvlenftilqvv
tnrdtqetllciayvfevsasehgaqhhifrlvke

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6geiL (L:)
dsetdlealfnavmnpktanvpqtvpmrlrklpdaffkppe

    Sequence, based on observed residues (ATOM records):
    >6geiL (L:)
dsetdlealfnavmnpktanvpqtvpmrlrklpdaffkpp