PDB entry 6ge5

View 6ge5 on RCSB PDB site
Description: tead4 (216-434);y429f complexed with yap peptide (60-100) and myristoate (covalently bound) at 2.05a (p41212 crystal form); myristoylation was done by adding myr-coa
Class: transcription
Keywords: transcription, co-activator, protein-protein interaction
Deposited on 2018-04-25, released 2018-09-19
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-10-31, with a file datestamp of 2018-10-26.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transcriptional enhancer factor TEF-3
    Species: Homo sapiens [TaxId:9606]
    Gene: TEAD4, RTEF1, TCF13L1, TEF3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q15561 (Start-218)
      • engineered mutation (213)
    Domains in SCOPe 2.08: d6ge5a_
  • Chain 'L':
    Compound: Transcriptional coactivator YAP1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: MYR, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ge5A (A:)
grsvassklwmlefsafleqqqdpdtynkhlfvhigqsspsysdpyleavdirqiydkfp
ekkgglkdlfergpsnafflvkfwadlntniedegssfygvssqyespenmiitcstkvc
sfgkqvvekveteyaryenghysyrihrsplceyminfihklkhlpekymmnsvlenfti
lqvvtnrdtqetllciayvfevsasehgaqhhifrlvke

    Sequence, based on observed residues (ATOM records): (download) 
    >6ge5A (A:)
rsvassklwmlefsafleqqqdpdtynkhlfvhigleavdirqiydkfpekkgglkdlfe
rgpsnafflvkfwadlntngssfygvssqyespenmiitcstkvcsfgkqvvekveteya
ryenghysyrihrsplceyminfihklkhlpekymmnsvlenftilqvvtnrdtqetllc
iayvfevsasehgaqhhifrlvke

  • Chain 'L':
    No sequence available.