PDB entry 6ge3
View 6ge3 on RCSB PDB site
Description: X-ray structure of TEAD4 (wildtype) complexed with YAP (wildtype): The role of residual flexibility and water molecules in the adaptation of a bound intrinsically disordered protein to mutations at a binding interface
Class: transcription
Keywords: transcription factor, co-activator, transcription regulation, TRANSCRIPTION
Deposited on
2018-04-25, released
2018-09-19
The last revision prior to the SCOPe 2.08 freeze date was dated
2018-10-31, with a file datestamp of
2018-10-26.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: N/A
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transcriptional enhancer factor TEF-3
Species: Homo sapiens [TaxId:9606]
Gene: TEAD4, RTEF1, TCF13L1, TEF3
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6ge3a_ - Chain 'L':
Compound: Transcriptional coactivator YAP1
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- Heterogens: MYR, GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6ge3A (A:)
grsvassklwmlefsafleqqqdpdtynkhlfvhigqsspsysdpyleavdirqiydkfp
ekkgglkdlfergpsnafflvkfwadlntniedegssfygvssqyespenmiitcstkvc
sfgkqvvekveteyaryenghysyrihrsplceyminfihklkhlpekymmnsvlenfti
lqvvtnrdtqetllciayvfevsasehgaqhhiyrlvke
Sequence, based on observed residues (ATOM records): (download)
>6ge3A (A:)
rsvassklwmlefsafleqqqdpdtynkhlfvhigleavdirqiydkfpekkgglkdlfe
rgpsnafflvkfwadlntngssfygvssqyespenmiitcstkvcsfgkqvvekveteya
ryenghysyrihrsplceyminfihklkhlpekymmnsvlenftilqvvtnrdtqetllc
iayvfevsasehgaqhhiyrlvke
- Chain 'L':
No sequence available.