PDB entry 6gcx
View 6gcx on RCSB PDB site
Description: Focal Adhesion Kinase catalytic domain in complex with irreversible inhibitor
Class: cell adhesion
Keywords: Focal Adhesion Kinase Cell Adhesion Signalling Irreversible inhibitor 2, 4-pyrimidine derivatives, CELL ADHESION
Deposited on
2018-04-19, released
2019-05-01
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-10-02, with a file datestamp of
2019-09-27.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.46
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Focal adhesion kinase 1
Species: Gallus gallus [TaxId:9031]
Gene: PTK2, FAK, FAK1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6gcxa_ - Heterogens: EUW, SO4, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6gcxA (A:)
strdyeiqrerielgrcigegqfgdvhqgiymspenpamavaiktcknctsdsvrekflq
ealtmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkfsldlaslilyayql
stalayleskrfvhrdiaarnvlvsatdcvklgdfglsrymedstyykaskgklpikwma
pesinfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncppt
lyslmtkcwaydpsrrprftelkaqlstileeeklq
Sequence, based on observed residues (ATOM records): (download)
>6gcxA (A:)
rdyeiqrerielgrcigegqfgdvhqgiymspenpamavaiktcknsdsvrekflqealt
mrqfdhphivkligvitenpvwiimelctlgelrsflqvrkfsldlaslilyayqlstal
ayleskrfvhrdiaarnvlvsatdcvklgdfglsrlpikwmapesinfrrftsasdvwmf
gvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrpr
ftelkaqlstileeeklq