PDB entry 6gcw

View 6gcw on RCSB PDB site
Description: Focal Adhesion Kinase catalytic domain in complex with irreversible inhibitor
Class: cell adhesion
Keywords: Focal Adhesion Kinase Cell Adhesion Signalling Irreversible inhibitor 2, 4-pyrimidine derivatives, CELL ADHESION
Deposited on 2018-04-19, released 2019-05-01
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-05-01, with a file datestamp of 2019-04-26.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Focal adhesion kinase 1
    Species: Gallus gallus [TaxId:9031]
    Gene: PTK2, FAK, FAK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6gcwa_
  • Chain 'B':
    Compound: Focal adhesion kinase 1
    Species: Gallus gallus [TaxId:9031]
    Gene: PTK2, FAK, FAK1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6gcwb_
  • Heterogens: EUQ, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6gcwA (A:)
    strdyeiqrerielgrcigegqfgdvhqgiymspenpamavaiktcknctsdsvrekflq
    ealtmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkfsldlaslilyayql
    stalayleskrfvhrdiaarnvlvsatdcvklgdfglsrymedstyykaskgklpikwma
    pesinfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncppt
    lyslmtkcwaydpsrrprftelkaqlstileeeklq
    

    Sequence, based on observed residues (ATOM records): (download)
    >6gcwA (A:)
    dyeiqrerielgrcigegqfgdvhqgiymspenpamavaiktcknctsdsvrekflqeal
    tmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkfsldlaslilyayqlsta
    layleskrfvhrdiaarnvlvsatdcvklgdflpikwmapesinfrrftsasdvwmfgvc
    mweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrprfte
    lkaqlstileeekl
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6gcwB (B:)
    strdyeiqrerielgrcigegqfgdvhqgiymspenpamavaiktcknctsdsvrekflq
    ealtmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkfsldlaslilyayql
    stalayleskrfvhrdiaarnvlvsatdcvklgdfglsrymedstyykaskgklpikwma
    pesinfrrftsasdvwmfgvcmweilmhgvkpfqgvknndvigriengerlpmppncppt
    lyslmtkcwaydpsrrprftelkaqlstileeeklq
    

    Sequence, based on observed residues (ATOM records): (download)
    >6gcwB (B:)
    dyeiqrerielgrcigegqfgdvhqgiymspenpamavaiktcknctsdsvrekflqeal
    tmrqfdhphivkligvitenpvwiimelctlgelrsflqvrkfsldlaslilyayqlsta
    layleskrfvhrdiaarnvlvsatdcvklgdfglsrlpikwmapesinfrrftsasdvwm
    fgvcmweilmhgvkpfqgvknndvigriengerlpmppncpptlyslmtkcwaydpsrrp
    rftelkaqlstileeeklq