PDB entry 6gcu

View 6gcu on RCSB PDB site
Description: met receptor in complex with inlb internalin domain and darpin a3a
Deposited on 2018-04-19, released 2019-05-15
The last revision was dated 2019-05-15, with a file datestamp of 2019-05-10.
Experiment type: XRAY
Resolution: 6 Å
R-factor: N/A
AEROSPACI score: -0.04 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: MET
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: internalin b
    Species: Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) [TaxId:169963]
    Gene: inlB, lmo0434
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25147 (3-End)
      • expression tag (2)
  • Chain 'C':
    Compound: DARPin A3A
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GCU
  • Chain 'D':
    Compound: Hepatocyte growth factor receptor
    Species: Homo sapiens [TaxId:9606]
    Gene: MET
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: internalin b
    Species: Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) [TaxId:169963]
    Gene: inlB, lmo0434
    Database cross-references and differences (RAF-indexed):
    • Uniprot P25147 (3-End)
      • expression tag (2)
  • Chain 'F':
    Compound: DARPin A3A
    Species: synthetic construct, synthetic [TaxId:32630]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GCU

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6gcuA (A:)
etreckealaksemnvnmkyqlpnftaetpiqnvilhehhiflgatnyiyvlneedlqkv
aeyktgpvlehpdcfpcqdcsskanlsggvwkdninmalvvdtyyddqliscgsvnrgtc
qrhvfphnhtadiqsevhcifspqieepsqcpdcvvsalgakvlssvkdrfinffvgnti
nssyfpdhplhsisvrrlketkdgfmfltdqsyidvlpefrdsypikyvhafesnnfiyf
ltvqretldaqtfhtriirfcsinsglhsymempleciltekrkkrstkkevfnilqaay
vskpgaqlarqigaslnddilfgvfaqskpdsaepmdrsamcafpikyvndffnkivnkn
nvrclqhfygpnhehcfnrtllrnssgcearrdeyrtefttalqrvdlfmgqfsevllts
istfikgdltianlgtsegrfmqvvvsrsgpstphvnflldshpvspevivehtlnqngy
tlvitgkkitkiplnglgcrhfqscsqclsappfvqcgwchdkcvrseeclsgtwtqqic
lpaiykvfpnsapleggtrlticgwdfgfrrnnkfdlkktrvllgnesctltlsestmnt
lkctvgpamnkhfnmsiiisnghgttqystfsyvdpvitsispkygpmaggtlltltgny
lnsgnsrhisiggktctlksvsnsilecytpaqtistefavklkidlanretsifsyred
lhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6gcuA (A:)
kyqlpnftaetpiqnvilhehhiflgatnyiyvlneedlqkvaeyktgpvlehpdcfpcq
dcsskanlsggvwkdninmalvvdtyyddqliscgsvnrgtcqrhvfphnhtadiqsevh
cifspqieepsqcpdcvvsalgakvlssvkdrfinffvgntinssyfpdhplhsisvrrl
ketkdgfmfltdqsyidvlpefrdsypikyvhafesnnfiyfltvqretldaqtfhtrii
rfcsinsglhsymempleciltkevfnilqaayvskpgaqlarqigaslnddilfgvfaq
skpdsaepmdrsamcafpikyvndffnkinvrclqhfygpnhehcfnrdeyrtefttalq
rvdlfmgqfsevlltsistfikgdltianlgtsegrfmqvvvsrsgpstphvnflldshp
vspevivehtlnqngytlvitgkkitkiplnglgcrhfqscsqclsappfvqcgwchdkc
vrseeclsgtwtqqiclpaiykvfpnsapleggtrlticgwdfgfrrnnkfdlkktrvll
gnesctltlsestmntlkctvgpamnkhfnmsiiisnghgttqystfsyvdpvitsispk
ygpmaggtlltltgnylnsgnsrhisiggktctlksvsnsilecytpaqtistefavklk
idlanretsifsyre

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6gcuB (B:)
gametitvptpikqifsddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvq
giqylpnvtklflngnkltdikplanlknlgwlfldenkvkdlsslkdlkklkslslehn
gisdinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqn
lylsknhisdlralaglknldvlelfsqeclnkpinhqsnlvvpntvkntdgslvtpeii
sddgdyekpnvkwhlpeftnevsfifyqpvtigkakarfhgrvtqplke

    Sequence, based on observed residues (ATOM records):
    >6gcuB (B:)
metitvptpikqifsddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvqgi
qylpnvtklflngnkltdikplanlknlgwlfldenkvkdlsslkdlkklkslslehngi
sdinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqnly
lsknhisdlralaglknldvlelfsqeclnkpinhqsnlvvpntvkntdgslvtpeiisd
dgdyekpnvkwhlpeftnevsfifyqpvtigkakarfhgrvtqplk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6gcuC (C:)
mrgshhhhhhgsdlgkklleaaragqddevrilmangadvnaadhygetplhraankghl
eivevllktgadvnakddwsgdtplhlaashghleivevllkagadvnamandgqtplhl
aasrghleivevllkhgadvnaqdkfgktpfdlaidngnediaevlqkaakln

    Sequence, based on observed residues (ATOM records):
    >6gcuC (C:)
dlgkklleaaragqddevrilmangadvnaadhygetplhraankghleivevllktgad
vnakddwsgdtplhlaashghleivevllkagadvnamandgqtplhlaasrghleivev
llkhgadvnaqdkfgktpfdlaidngnediaevlq

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6gcuD (D:)
etreckealaksemnvnmkyqlpnftaetpiqnvilhehhiflgatnyiyvlneedlqkv
aeyktgpvlehpdcfpcqdcsskanlsggvwkdninmalvvdtyyddqliscgsvnrgtc
qrhvfphnhtadiqsevhcifspqieepsqcpdcvvsalgakvlssvkdrfinffvgnti
nssyfpdhplhsisvrrlketkdgfmfltdqsyidvlpefrdsypikyvhafesnnfiyf
ltvqretldaqtfhtriirfcsinsglhsymempleciltekrkkrstkkevfnilqaay
vskpgaqlarqigaslnddilfgvfaqskpdsaepmdrsamcafpikyvndffnkivnkn
nvrclqhfygpnhehcfnrtllrnssgcearrdeyrtefttalqrvdlfmgqfsevllts
istfikgdltianlgtsegrfmqvvvsrsgpstphvnflldshpvspevivehtlnqngy
tlvitgkkitkiplnglgcrhfqscsqclsappfvqcgwchdkcvrseeclsgtwtqqic
lpaiykvfpnsapleggtrlticgwdfgfrrnnkfdlkktrvllgnesctltlsestmnt
lkctvgpamnkhfnmsiiisnghgttqystfsyvdpvitsispkygpmaggtlltltgny
lnsgnsrhisiggktctlksvsnsilecytpaqtistefavklkidlanretsifsyred
lhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6gcuD (D:)
kyqlpnftaetpiqnvilhehhiflgatnyiyvlneedlqkvaeyktgpvlehpdcfpcq
dcsskanlsggvwkdninmalvvdtyyddqliscgsvnrgtcqrhvfphnhtadiqsevh
cifspqieepsqcpdcvvsalgakvlssvkdrfinffvgntinssyfpdhplhsisvrrl
ketkdgfmfltdqsyidvlpefrdsypikyvhafesnnfiyfltvqretldaqtfhtrii
rfcsinsglhsymempleciltkevfnilqaayvskpgaqlarqigaslnddilfgvfaq
skpdsaepmdrsamcafpikyvndffnkinvrclqhfygpnhehcfnrdeyrtefttalq
rvdlfmgqfsevlltsistfikgdltianlgtsegrfmqvvvsrsgpstphvnflldshp
vspevivehtlnqngytlvitgkkitkiplnglgcrhfqscsqclsappfvqcgwchdkc
vrseeclsgtwtqqiclpaiykvfpnsapleggtrlticgwdfgfrrnnkfdlkktrvll
gnesctltlsestmntlkctvgpamnkhfnmsiiisnghgttqystfsyvdpvitsispk
ygpmaggtlltltgnylnsgnsrhisiggktctlksvsnsilecytpaqtistefavklk
idlanretsifsyre

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6gcuE (E:)
gametitvptpikqifsddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvq
giqylpnvtklflngnkltdikplanlknlgwlfldenkvkdlsslkdlkklkslslehn
gisdinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqn
lylsknhisdlralaglknldvlelfsqeclnkpinhqsnlvvpntvkntdgslvtpeii
sddgdyekpnvkwhlpeftnevsfifyqpvtigkakarfhgrvtqplke

    Sequence, based on observed residues (ATOM records):
    >6gcuE (E:)
metitvptpikqifsddafaetikdnlkkksvtdavtqnelnsidqiiannsdiksvqgi
qylpnvtklflngnkltdikplanlknlgwlfldenkvkdlsslkdlkklkslslehngi
sdinglvhlpqleslylgnnkitditvlsrltkldtlslednqisdivplagltklqnly
lsknhisdlralaglknldvlelfsqeclnkpinhqsnlvvpntvkntdgslvtpeiisd
dgdyekpnvkwhlpeftnevsfifyqpvtigkakarfhgrvtqplk

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6gcuF (F:)
mrgshhhhhhgsdlgkklleaaragqddevrilmangadvnaadhygetplhraankghl
eivevllktgadvnakddwsgdtplhlaashghleivevllkagadvnamandgqtplhl
aasrghleivevllkhgadvnaqdkfgktpfdlaidngnediaevlqkaakln

    Sequence, based on observed residues (ATOM records):
    >6gcuF (F:)
dlgkklleaaragqddevrilmangadvnaadhygetplhraankghleivevllktgad
vnakddwsgdtplhlaashghleivevllkagadvnamandgqtplhlaasrghleivev
llkhgadvnaqdkfgktpfdlaidngnediaevlq