PDB entry 6gcl

View 6gcl on RCSB PDB site
Description: Trypanosoma brucei PTR1 in complex with inhibitor 3a (F020)
Class: oxidoreductase
Keywords: OXIDOREDUCTASE, Trypanosoma brucei, pteridine reductase, PTR1, TbPTR1, benzothiazole
Deposited on 2018-04-18, released 2019-04-03
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-05-08, with a file datestamp of 2019-05-03.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: pteridine reductase
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Gene: PTR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6gcla_
  • Chain 'B':
    Compound: pteridine reductase
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Gene: PTR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6gclb_
  • Chain 'C':
    Compound: pteridine reductase
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Gene: PTR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6gclc_
  • Chain 'D':
    Compound: pteridine reductase
    Species: Trypanosoma brucei brucei [TaxId:5702]
    Gene: PTR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6gcld_
  • Heterogens: NAP, EUE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6gclA (A:)
mgsshhhhhhssglvprgshmeapaavvtgaakrigraiavklhqtgyrvvihyhnsaea
avsladelnkersntavvcqadltnsnvlpasceeiinscfrafgrcdvlvnnasafypt
plvqgdhednsngktvetqvaeligtnaiapflltmsfaqrqkgtnpnctssnlsivnlc
damvdqpcmafslynmgkhalvgltqsaalelapygirvngvapgvsllpvamgeeekdk
wrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvdgglslvha

    Sequence, based on observed residues (ATOM records): (download) 
    >6gclA (A:)
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvqgktvetqvaeligtnai
apflltmsfaqrqsnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygir
vngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiik
vdgglslvha

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6gclB (B:)
mgsshhhhhhssglvprgshmeapaavvtgaakrigraiavklhqtgyrvvihyhnsaea
avsladelnkersntavvcqadltnsnvlpasceeiinscfrafgrcdvlvnnasafypt
plvqgdhednsngktvetqvaeligtnaiapflltmsfaqrqkgtnpnctssnlsivnlc
damvdqpcmafslynmgkhalvgltqsaalelapygirvngvapgvsllpvamgeeekdk
wrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvdgglslvha

    Sequence, based on observed residues (ATOM records): (download) 
    >6gclB (B:)
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvgktvetqvaeligtnaia
pflltmsfaqrqsnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygirv
ngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiikv
dgglslvha

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6gclC (C:)
mgsshhhhhhssglvprgshmeapaavvtgaakrigraiavklhqtgyrvvihyhnsaea
avsladelnkersntavvcqadltnsnvlpasceeiinscfrafgrcdvlvnnasafypt
plvqgdhednsngktvetqvaeligtnaiapflltmsfaqrqkgtnpnctssnlsivnlc
damvdqpcmafslynmgkhalvgltqsaalelapygirvngvapgvsllpvamgeeekdk
wrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvdgglslvha

    Sequence, based on observed residues (ATOM records): (download) 
    >6gclC (C:)
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvktvetqvaeligtnaiap
flltmsfaqrqsnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygirvn
gvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvd
gglslvha

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6gclD (D:)
mgsshhhhhhssglvprgshmeapaavvtgaakrigraiavklhqtgyrvvihyhnsaea
avsladelnkersntavvcqadltnsnvlpasceeiinscfrafgrcdvlvnnasafypt
plvqgdhednsngktvetqvaeligtnaiapflltmsfaqrqkgtnpnctssnlsivnlc
damvdqpcmafslynmgkhalvgltqsaalelapygirvngvapgvsllpvamgeeekdk
wrrkvplgrreasaeqiadaviflvsgsaqyitgsiikvdgglslvha

    Sequence, based on observed residues (ATOM records): (download) 
    >6gclD (D:)
eapaavvtgaakrigraiavklhqtgyrvvihyhnsaeaavsladelnkersntavvcqa
dltnsnvlpasceeiinscfrafgrcdvlvnnasafyptplvgktvetqvaeligtnaia
pflltmsfaqrqsnlsivnlcdamvdqpcmafslynmgkhalvgltqsaalelapygirv
ngvapgvsllpvamgeeekdkwrrkvplgrreasaeqiadaviflvsgsaqyitgsiikv
dgglslvha