PDB entry 6gc2

View 6gc2 on RCSB PDB site
Description: AbLIFT: Antibody stability and affinity optimization by computational design of the variable light-heavy chain interface
Class: immune system
Keywords: Antibody, Immune system
Deposited on 2018-04-17, released 2019-05-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-09-04, with a file datestamp of 2019-08-30.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: heavy chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GC2 (0-End)
    Domains in SCOPe 2.08: d6gc2h1, d6gc2h2
  • Chain 'L':
    Compound: light chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6GC2
    Domains in SCOPe 2.08: d6gc2l_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6gc2H (H:)
qvqlqesgaevmkpgasvkisckatgytfstywiewmkqrpgggleyigeilpgsgstyy
nekfkgkatftadtssntaymqlssltsedsavyycargdgyykywgqgttltvssastk
gpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglys
lssvvtvpssslgtqtyicnvnhkpsntkvdkrvepkscdqthhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6gc2H (H:)
qvqlqesgaevmkpgasvkisckatgytfstywiewmkqrpgggleyigeilpgsgstyy
nekfkgkatftadtssntaymqlssltsedsavyycargdgyykywgqgttltvssastk
gpsvfplapssktaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslssvv
tvpssslgtqtyicnvnhkpsntkvdkrvepks

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6gc2L (L:)
mgwsciilflvatatgvhsdieltqspatlsvtpgdsvslscrasqsisnnlhwyqqksh
epprllikyvsqsvsgipsrfsgsgsgtdftlsinsvetedfgmyfcgqsnswprtfggg
tkleikrtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqe
svteqdskdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgecmgwscii
lflvatatgvhc

    Sequence, based on observed residues (ATOM records): (download) 
    >6gc2L (L:)
dieltqspatlsvtpgdsvslscrasqsisnnlhwyqqkshepprllikyvsqsvsgips
rfsgsgsgtdftlsinsvetedfgmyfcgqsnswprtfgggtkleikrtvaapsvfifpp
sdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqdskdstyslsstlt
lskadyekhkvyacevthqglsspvtksfnrgec