PDB entry 6gbw

View 6gbw on RCSB PDB site
Description: thrombin in complex with mi2100 ((s)-n-(2-(aminomethyl)-5- chlorobenzyl)-1-((benzylsulfonyl)-l-arginyl)pyrrolidine-2- carboxamide)
Deposited on 2018-04-16, released 2019-04-24
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: N/A
AEROSPACI score: 0.6 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'H':
    Compound: Prothrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Hirudin variant-2
    Species: Hirudo medicinalis, synthetic [TaxId:6421]
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: Prothrombin
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NAG, NA, DMS, EU5, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6gbwH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketwtanvgkgqpsvlqvvnlpiverpvckdstrir
itdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfy
thvfrlkkwiqkvidqfge

    Sequence, based on observed residues (ATOM records):
    >6gbwH (H:)
ivegsdaeigmspwqvmlfrkspqellcgaslisdrwvltaahcllyppwdknftendll
vrigkhsrtryerniekismlekiyihprynwrenldrdialmklkkpvafsdyihpvcl
pdretaasllqagykgrvtgwgnlketgqpsvlqvvnlpiverpvckdstriritdnmfc
agykpdegkrgdacegdsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlk
kwiqkvidqf

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6gbwI (I:)
gdfeeipeeylq

    Sequence, based on observed residues (ATOM records):
    >6gbwI (I:)
dfeeipeeylq

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6gbwL (L:)
tfgsgeadcglrplfekksledkterellesyidgr

    Sequence, based on observed residues (ATOM records):
    >6gbwL (L:)
eadcglrplfekksledkterellesyi