PDB entry 6g9i

View 6g9i on RCSB PDB site
Description: Crystal structure of Ebolavirus glycoprotein in complex with clomipramine
Class: viral protein
Keywords: Ebolavirus Glycoprotein, Clomipramine, Protein drug complex, viral protein
Deposited on 2018-04-10, released 2018-05-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.19 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Envelope glycoprotein,Envelope glycoprotein
    Species: Ebola virus - Mayinga, Zaire, 1976 [TaxId:128952]
    Gene: GP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q05320 (4-283)
      • engineered mutation (14)
      • linker (284-290)
    • Uniprot Q05320
    Domains in SCOPe 2.08: d6g9ia1, d6g9ia2
  • Chain 'B':
    Compound: Envelope glycoprotein,Envelope glycoprotein
    Species: Human immunodeficiency virus 1 [TaxId:11676]
    Gene: GP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q05320 (0-End)
      • engineered mutation (111)
    • Uniprot M1E1E4
  • Heterogens: CXX, NAG, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6g9iA (A:)
etgrsiplgvihnsalqvsdvdklvcrdklsstnqlrsvglnlegngvatdvpsatkrwg
frsgvppkvvnyeagewaencynleikkpdgseclpaapdgirgfprcryvhkvsgtgpc
agdfafhkegafflydrlastviyrgttfaegvvaflilpqakkdffsshplrepvnate
dpssgyysttiryqatgfgtneteylfevdnltyvqlesrftpqfllqlnetiytsgkrs
nttgkliwkvnpeidttigewafwetkknltrkirseelsftvvxxxxxxxsthhqdtge
esassgklglitntiagvaglitggrrtrr

    Sequence, based on observed residues (ATOM records): (download) 
    >6g9iA (A:)
siplgvihnsalqvsdvdklvcrdklsstnqlrsvglnlegngvatdvpsatkrwgfrsg
vppkvvnyeagewaencynleikkpdgseclpaapdgirgfprcryvhkvsgtgpcagdf
afhkegafflydrlastviyrgttfaegvvaflilpqasgyysttiryqatgfgtnetey
lfevdnltyvqlesrftpqfllqlnetiytsgkrsnttgkliwkvnpeidtewafwetls
ftvvxxxxxxx

  • Chain 'B':
    No sequence available.