PDB entry 6g95

View 6g95 on RCSB PDB site
Description: Crystal structure of Ebolavirus glycoprotein in complex with thioridazine
Class: viral protein
Keywords: Ebolavirus Glycoprotein, Thioridazine, Protein drug complex, Viral protein
Deposited on 2018-04-10, released 2018-05-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.31 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Envelope glycoprotein
    Species: Zaire ebolavirus (strain Mayinga-76) [TaxId:128952]
    Gene: GP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q05320 (4-283)
      • engineered mutation (14)
      • expression tag (284-290)
    Domains in SCOPe 2.08: d6g95a1, d6g95a2
  • Chain 'B':
    Compound: Envelope glycoprotein
    Species: Zaire ebolavirus (strain Mayinga-76) [TaxId:128952]
    Gene: GP
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q05320 (0-End)
      • engineered mutation (111)
  • Heterogens: RTZ, NAG, GOL, DMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6g95A (A:)
etgrsiplgvihnsalqvsdvdklvcrdklsstnqlrsvglnlegngvatdvpsatkrwg
frsgvppkvvnyeagewaencynleikkpdgseclpaapdgirgfprcryvhkvsgtgpc
agdfafhkegafflydrlastviyrgttfaegvvaflilpqakkdffsshplrepvnate
dpssgyysttiryqatgfgtneteylfevdnltyvqlesrftpqfllqlnetiytsgkrs
nttgkliwkvnpeidttigewafwetkknltrkirseelsftvvxxxxxxxsthhqdtge
esassgklglitntiagvaglitggrrtrr

    Sequence, based on observed residues (ATOM records): (download) 
    >6g95A (A:)
siplgvihnsalqvsdvdklvcrdklsstnqlrsvglnlegngvatdvpsatkrwgfrsg
vppkvvnyeagewaencynleikkpdgseclpaapdgirgfprcryvhkvsgtgpcagdf
afhkegafflydrlastviyrgttfaegvvaflilpqasgyysttiryqatgfgtnetey
lfevdnltyvqlesrftpqfllqlnetiytsgkrsnttgkliwkvnpeidtewafwetse
elsftvvxxxxxxx

  • Chain 'B':
    No sequence available.