SCOPe 2.08: Structural Classification of Proteins

PDB entry 6g79

View 6g79 on RCSB PDB site
Description: coupling specificity of heterotrimeric go to the serotonin 5-ht1b receptor
Deposited on 2018-04-05, released 2018-06-20
The last revision was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: EM
Resolution: 3.78 Å
R-factor: N/A
AEROSPACI score: 0.06 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: Guanine nucleotide-binding protein G(o) subunit alpha
Species: Homo sapiens [TaxId:9606]
Gene: GNAO1
Database cross-references and differences (RAF-indexed):
- Uniprot P09471
  - conflict (38-39)
- Uniprot A0A0P7W0C8 (Start-224)
  - conflict (107)
  - conflict (111)
  - conflict (146)
  - conflict (153)
  - conflict (155)
  - conflict (200)
  - conflict (202)
  - conflict (205)
Chain 'B':
Compound: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
Species: Homo sapiens [TaxId:9606]
Gene: GNB1
Database cross-references and differences (RAF-indexed):
- Uniprot P62873 (Start-338)
Chain 'G':
Compound: Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2
Species: Homo sapiens [TaxId:9606]
Gene: GNG2
Database cross-references and differences (RAF-indexed):
- Uniprot P59768
Chain 'S':
Compound: 5-hydroxytryptamine receptor 1B
Species: Homo sapiens [TaxId:9606]
Gene: HTR1B, HTR1DB
Database cross-references and differences (RAF-indexed):
- Uniprot P28222
  - conflict (105)
Heterogens: EP5

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

Chain 'A':
Sequence, based on SEQRES records:

>6g79A (A:)
tlsaeeraalerskaieknlkedgisaakdvkllllgadnsgkstivkqmkiihggsggs
ggttgivethftfknlhfrlfdvggqrserkkwihcfedvtaiifcvdlsdynrmheslm
lfdsicnnkffidtsiilflnkkdlfgekikksplticfpeytgpntyedaaayiqaqfe
sknrspnkeiychmtcatdtnnaqvifdavtdiiiannlrgcgly

Sequence, based on observed residues (ATOM records):

>6g79A (A:)
lsaeeraalerskaieknlkedgisaakdvkllllgadnsgkstivkqmktgivethftf
knlhfrlfdvggqrserkkwihcfedvtaiifcvdlsdynrmheslmlfdsicnnkffid
tsiilflnkkdlfgekikksplticfpgpntyedaaayiqaqfesknrspnkeiychmtc
atdtnnaqvifdavtdiiiannlrgcgly

Chain 'B':
Sequence, based on SEQRES records:

>6g79B (B:)
seldqlrqeaeqlknqirdarkacadatlsqitnnidpvgriqmrtrrtlrghlakiyam
hwgtdsrllvsasqdgkliiwdsyttnkvhaiplrsswvmtcayapsgnyvacggldnic
siynlktregnvrvsrelaghtgylsccrflddnqivtssgdttcalwdietgqqtttft
ghtgdvmslslapdtrlfvsgacdasaklwdvregmcrqtftghesdinaicffpngnaf
atgsddatcrlfdlradqelmtyshdniicgitsvsfsksgrlllagyddfncnvwdalk
adragvlaghdnrvsclgvtddgmavatgswdsflkiwn

Sequence, based on observed residues (ATOM records):

>6g79B (B:)
eldqlrqeaeqlknqirdarkacadatlsqitnnidpvgriqmrtrrtlrghlakiyamh
wgtdsrllvsasqdgkliiwdsyttnkvhaiplrsswvmtcayapsgnyvacggldnics
iynlnvrvsrelaghtgylsccrflddnqivtssgdttcalwdietgqqtttftghtgdv
mslslapdtrlfvsgacdasaklwdvregmcrqtftghesdinaicffpngnafatgsdd
atcrlfdlradqelmtyshdniicgitsvsfsksgrlllagyddfncnvwdalkadragv
laghdnrvsclgvtddgmavatgswdsflkiwn

Chain 'G':
Sequence, based on SEQRES records:

>6g79G (G:)
masnntasiaqarklveqlkmeanidrikvskaaadlmayceahakedplltpvpasenp
frekkffsail

Sequence, based on observed residues (ATOM records):

>6g79G (G:)
asiaqarklveqlkmeanidrikvskaaadlmayceahakedplltpvpasenpfr

Chain 'S':
Sequence, based on SEQRES records:

>6g79S (S:)
msakdyiyqdsislpwkvllvmllalitlattlsnafviatvyrtrklhtpanyliasla
vtdllvsilvmpistmytvtgrwtlgqvvcdfwlssditcctasiwhlcvialdrywait
daveysakrtpkraavmialvwvfsisislppffwrqakaeeevsecvvntdhilytvys
tvgafyfptlllialygriyvearsrilkqtpnrtgkrltraqlitdspgstssvtsins
rvpdvpsesgspvyvnqvkvrvsdallekkklmaarerkatktlgiilgafivcwlpffi
islvmpickdacwfhlaifdfftwlgylnslinpiiytmsnedfkqafhklirfkctsen
lyfq

Sequence, based on observed residues (ATOM records):

>6g79S (S:)
slpwkvllvmllalitlattlsnafviatvyrtrklhtpanyliaslavtdllvsilvmp
istmytvtgrwtlgqvvcdfwlssditcctasiwhlcvialdrywaitdaveysakrtpk
raavmialvwvfsisislppffwsecvvntdhilytvystvgafyfptlllialygriyv
earsrilmaarerkatktlgiilgafivcwlpffiislvmpwfhlaifdfftwlgylnsl
inpiiytmsnedfkqafhklir