PDB entry 6g5k

View 6g5k on RCSB PDB site
Description: crystal structure of the binding domain of botulinum neurotoxin type b in complex with human synaptotagmin 1
Deposited on 2018-03-29, released 2019-01-16
Made obsolete on 2022-09-20

The last revision was dated 2019-02-20, with a file datestamp of 2019-02-15.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: botulinum neurotoxin type b
    Species: Clostridium botulinum [TaxId:1491]
    Gene: botB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10844 (Start-458)
      • expression tag (459-460)
  • Chain 'B':
    Compound: botulinum neurotoxin type b
    Species: Clostridium botulinum [TaxId:1491]
    Gene: botB
    Database cross-references and differences (RAF-indexed):
    • Uniprot P10844 (Start-458)
      • expression tag (459-460)
  • Chain 'C':
    Compound: Synaptotagmin-1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Synaptotagmin-1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6g5kA (A:)
mgsshhhhhhssglvprgshmasmnseilnniilnlrykdnnlidlsgygakvevydgve
lndknqfkltssanskirvtqnqniifnsvfldfsvsfwiripkykndgiqnyihneyti
incmknnsgwkisirgnriiwtlidingktksvffeynirediseyinrwffvtitnnln
nakiyingklesntdikdireviangeiifkldgdidrtqfiwmkyfsifntelsqsnie
erykiqsyseylkdfwgnplmynkeyymfnagnknsyiklkkdspvgeiltrskynqnsk
yinyrdlyigekfiirrksnsqsinddivrkedyiyldffnlnqewrvytykyfkkeeek
lflapisdsdefyntiqikeydeqptyscqllfkkdeestdeigligihrfyesgivfee
ykdyfciskwylkevkrkpynlklgcnwqfipkdegwtelq

    Sequence, based on observed residues (ATOM records):
    >6g5kA (A:)
lnniilnlrykdnnlidlsgygakvevydgvelndknqfkltssanskirvtqnqniifn
svfldfsvsfwiripkykndgiqnyihneytiincmknnsgwkisirgnriiwtliding
ktksvffeynirediseyinrwffvtitnnlnnakiyingklesntdikdireviangei
ifkldgdidrtqfiwmkyfsifntelsqsnieerykiqsyseylkdfwgnplmynkeyym
fnagnknsyiklkkdspvgeiltrskynqnskyinyrdlyigekfiirrksddivrkedy
iyldffnlnqewrvytykyfkkeeeklflapisdsdefyntiqikeydeqptyscqllfk
kdeestdeigligihrfyeeykdyfciskwylkevkrkpynlklgcnwqfipkdegwtel
q

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6g5kB (B:)
mgsshhhhhhssglvprgshmasmnseilnniilnlrykdnnlidlsgygakvevydgve
lndknqfkltssanskirvtqnqniifnsvfldfsvsfwiripkykndgiqnyihneyti
incmknnsgwkisirgnriiwtlidingktksvffeynirediseyinrwffvtitnnln
nakiyingklesntdikdireviangeiifkldgdidrtqfiwmkyfsifntelsqsnie
erykiqsyseylkdfwgnplmynkeyymfnagnknsyiklkkdspvgeiltrskynqnsk
yinyrdlyigekfiirrksnsqsinddivrkedyiyldffnlnqewrvytykyfkkeeek
lflapisdsdefyntiqikeydeqptyscqllfkkdeestdeigligihrfyesgivfee
ykdyfciskwylkevkrkpynlklgcnwqfipkdegwtelq

    Sequence, based on observed residues (ATOM records):
    >6g5kB (B:)
ilnniilnlrykdnnlidlsgygakvevydgvelndknqfkltssanskirvtqnqniif
nsvfldfsvsfwiripkykndgiqnyihneytiincmknnsgwkisirgnriiwtlidin
gktksvffeynirediseyinrwffvtitnnlnnakiyingklesntdikdireviange
iifkldgdidrtqfiwmkyfsifntelsqsnieerykiqsyseylkdfwgnplmynkeyy
mfnagnknsyiklkkdspvgeiltrskynqnskyinyrdlyigekfiirrksddivrked
yiyldffnlnqewrvytykyfkkeeeklflapisdsdefyntiqikeydeqptyscqllf
kkdeestdeigligihrfyefeeykdyfciskwylkevkrkpynlklgcnwqfipkdegw
telq

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6g5kC (C:)
gegkedafsklkekfmnelhk

    Sequence, based on observed residues (ATOM records):
    >6g5kC (C:)
dafsklkekfmnelhk

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6g5kD (D:)
gegkedafsklkekfmnelhk

    Sequence, based on observed residues (ATOM records):
    >6g5kD (D:)
dafsklkekfmnelh