PDB entry 6g54

View 6g54 on RCSB PDB site
Description: Crystal structure of ERK2 covalently bound to SM1-71
Class: transferase
Keywords: kinase, covalent inhibitor, MAPK, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2018-03-29, released 2019-02-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-02-27, with a file datestamp of 2019-02-22.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Mitogen-activated protein kinase 1
    Species: Homo sapiens [TaxId:9606]
    Gene: MAPK1, ERK2, PRKM1, PRKM2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6g54a_
  • Heterogens: SO4, 6H3, EDO, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6g54A (A:)
smaaaaaagagpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispf
ehqtycqrtlreikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktq
hlsndhicyflyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhd
htgflteyvatrwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnh
ilgilgspsqedlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnph
krieveqalahpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqpgyr
s

    Sequence, based on observed residues (ATOM records): (download) 
    >6g54A (A:)
gpemvrgqvfdvgprytnlsyigegaygmvcsaydnvnkvrvaikkispfehqtycqrtl
reikillrfrheniigindiiraptieqmkdvyivqdlmetdlykllktqhlsndhicyf
lyqilrglkyihsanvlhrdlkpsnlllnttcdlkicdfglarvadpdhdhtgflteyva
trwyrapeimlnskgytksidiwsvgcilaemlsnrpifpgkhyldqlnhilgilgspsq
edlnciinlkarnyllslphknkvpwnrlfpnadskaldlldkmltfnphkrieveqala
hpyleqyydpsdepiaeapfkfdmelddlpkeklkelifeetarfqp