PDB entry 6g40

View 6g40 on RCSB PDB site
Description: Structure of the mouse 8-oxoguanine DNA Glycosylase mOGG1 in complex with ligand TH9525
Class: DNA binding protein
Keywords: N-glycosylase, DNA lyase, DNA BINDING PROTEIN
Deposited on 2018-03-26, released 2019-04-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-10, with a file datestamp of 2019-07-05.
Experiment type: XRAY
Resolution: 2.49 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: N-glycosylase/DNA lyase
    Species: Mus musculus [TaxId:10090]
    Gene: OGG1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O08760 (Start-317)
      • conflict (2)
    Domains in SCOPe 2.08: d6g40a1, d6g40a2
  • Chain 'B':
    Compound: N-glycosylase/DNA lyase
    Species: Mus musculus [TaxId:10090]
    Gene: OGG1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O08760 (Start-317)
      • conflict (2)
    Domains in SCOPe 2.08: d6g40b1, d6g40b2
  • Chain 'C':
    Compound: N-glycosylase/DNA lyase
    Species: Mus musculus [TaxId:10090]
    Gene: OGG1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O08760 (1-End)
      • expression tag (0)
      • conflict (2)
    Domains in SCOPe 2.08: d6g40c1, d6g40c2, d6g40c3
  • Heterogens: ELK, PEG, NI, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6g40A (A:)
gshmrhrtlssspalwasipcprselrldlvlasgqsfrwkeqspahwsgvladqvwtlt
qtedqlyctvyrgddsqvsrptleeletlhkyfqldvslaqlyshwasvdshfqrvaqkf
qgvrllrqdpteclfsficssnnniaritgmverlcqafgprliqlddvtyhgfpnlhal
agpeaethlrklglgyraryvrasakaileeqggpawlqqlrvapyeeahkalctlpgvg
akvadciclmaldkpqavpvdvhvwqiahrdygwhpktsqakgpsplankelgnffrnlw
gpyagwaqavlfsadlrq

    Sequence, based on observed residues (ATOM records): (download) 
    >6g40A (A:)
hmrhrtlssspalwasipcprselrldlvlasgqsfrwkeqspahwsgvladqvwtltqt
edqlyctvyrgddsqvsrptleeletlhkyfqldvslaqlyshwasvdshfqrvaqkfqg
vrllrqdpteclfsficssnnniaritgmverlcqafgprliqlddvtyhgfpnlhalag
peaethlrklglgyraryvrasakaileeqggpawlqqlrvapyeeahkalctlpgvgak
vadciclmaldkpqavpvdvhvwqiahrdygwhpktsqakgpsplankelgnffrnlwgp
yagwaqavlfsadlrq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6g40B (B:)
gshmrhrtlssspalwasipcprselrldlvlasgqsfrwkeqspahwsgvladqvwtlt
qtedqlyctvyrgddsqvsrptleeletlhkyfqldvslaqlyshwasvdshfqrvaqkf
qgvrllrqdpteclfsficssnnniaritgmverlcqafgprliqlddvtyhgfpnlhal
agpeaethlrklglgyraryvrasakaileeqggpawlqqlrvapyeeahkalctlpgvg
akvadciclmaldkpqavpvdvhvwqiahrdygwhpktsqakgpsplankelgnffrnlw
gpyagwaqavlfsadlrq

    Sequence, based on observed residues (ATOM records): (download) 
    >6g40B (B:)
hmrhrtlssspalwasipcprselrldlvlasgqsfrwkeqspahwsgvladqvwtltqt
edqlyctvyrgddsqvsrptleeletlhkyfqldvslaqlyshwasvdshfqrvaqkfqg
vrllrqdpteclfsficssnnniaritgmverlcqafgprliqlddvtyhgfpnlhalag
peaethlrklglgyraryvrasakaileeqggpawlqqlrvapyeeahkalctlpgvgak
vadciclmaldkpqavpvdvhvwqiahrdygwhpktsqakgpsplankelgnffrnlwgp
yagwaqavlfsadlrq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6g40C (C:)
gshmrhrtlssspalwasipcprselrldlvlasgqsfrwkeqspahwsgvladqvwtlt
qtedqlyctvyrgddsqvsrptleeletlhkyfqldvslaqlyshwasvdshfqrvaqkf
qgvrllrqdpteclfsficssnnniaritgmverlcqafgprliqlddvtyhgfpnlhal
agpeaethlrklglgyraryvrasakaileeqggpawlqqlrvapyeeahkalctlpgvg
akvadciclmaldkpqavpvdvhvwqiahrdygwhpktsqakgpsplankelgnffrnlw
gpyagwaqavlfsadlrq

    Sequence, based on observed residues (ATOM records): (download) 
    >6g40C (C:)
gshmrhrtlssspalwasipcprselrldlvlasgqsfrwkeqspahwsgvladqvwtlt
qtedqlyctvyrgddvsrptleeletlhkyfqldvslaqlyshwasvdshfqrvaqkfqg
vrllrqdpteclfsficssnnniaritgmverlcqafgprliqlddvtyhgfpnlhalag
peaethlrklglgyraryvrasakaileeqggpawlqqlrvapyeeahkalctlpgvgak
vadciclmaldkpqavpvdvhvwqiahrdygwhpktsqakgpsplankelgnffrnlwgp
yagwaqavlfsadlr