PDB entry 6g3o

View 6g3o on RCSB PDB site
Description: crystal structure of human hdac2 in complex with (r)-6-[3,4-dioxo-2- (4-trifluoromethoxy-phenylamino)-cyclobut-1-enylamino]-heptanoic acid hydroxyamide
Deposited on 2018-03-26, released 2018-06-27
The last revision was dated 2018-08-29, with a file datestamp of 2018-08-24.
Experiment type: XRAY
Resolution: 2.27 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Histone deacetylase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: HDAC2
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Histone deacetylase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: HDAC2
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Histone deacetylase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: HDAC2
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ZN, CA, NA, EL8, 1PE, SO4, PG4, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6g3oA (A:)
ggkkkvcyyydgdignyyygqghpmkphrirmthnlllnyglyrkmeiyrphkataeemt
kyhsdeyikflrsirpdnmseyskqmqrfnvgedcpvfdglfefcqlstggsvagavkln
rqqtdmavnwagglhhakkseasgfcyvndivlailellkyhqrvlyididihhgdgvee
afyttdrvmtvsfhkygeyfpgtgdlrdigagkgkyyavnfpmrdgiddesygqifkpii
skvmemyqpsavvlqcgadslsgdrlgcfnltvkghakcvevvktfnlpllmlggggyti
rnvarcwtyetavaldceipnelpyndyfeyfgpdfklhispsnmtnqntpeymekikqr
lfenlrmlph

    Sequence, based on observed residues (ATOM records):
    >6g3oA (A:)
ggkkkvcyyydgdignyyygqghpmkphrirmthnlllnyglyrkmeiyrphkataeemt
kyhsdeyikflrsirpdnmseyskqmqrfnvgedcpvfdglfefcqlstggsvagavkln
rqqtdmavnwagglhhakkseasgfcyvndivlailellkyhqrvlyididihhgdgvee
afyttdrvmtvsfhkygeyfpgtgdlrdigagkgkyyavnfpmrdgiddesygqifkpii
skvmemyqpsavvlqcgadslsgdrlgcfnltvkghakcvevvktfnlpllmlggggyti
rnvarcwtyetavaldceipnelpyndyfeyfgpdfklhispsnmtnqntpeymekikqr
lfenlrmlp

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6g3oB (B:)
ggkkkvcyyydgdignyyygqghpmkphrirmthnlllnyglyrkmeiyrphkataeemt
kyhsdeyikflrsirpdnmseyskqmqrfnvgedcpvfdglfefcqlstggsvagavkln
rqqtdmavnwagglhhakkseasgfcyvndivlailellkyhqrvlyididihhgdgvee
afyttdrvmtvsfhkygeyfpgtgdlrdigagkgkyyavnfpmrdgiddesygqifkpii
skvmemyqpsavvlqcgadslsgdrlgcfnltvkghakcvevvktfnlpllmlggggyti
rnvarcwtyetavaldceipnelpyndyfeyfgpdfklhispsnmtnqntpeymekikqr
lfenlrmlph

    Sequence, based on observed residues (ATOM records):
    >6g3oB (B:)
kkvcyyydgdignyyygqghpmkphrirmthnlllnyglyrkmeiyrphkataeemtkyh
sdeyikflrsirpdnmseyskqmqrfnvgedcpvfdglfefcqlstggsvagavklnrqq
tdmavnwagglhhakkseasgfcyvndivlailellkyhqrvlyididihhgdgveeafy
ttdrvmtvsfhkygeyfpgtgdlrdigagkgkyyavnfpmrdgiddesygqifkpiiskv
memyqpsavvlqcgadslsgdrlgcfnltvkghakcvevvktfnlpllmlggggytirnv
arcwtyetavaldceipnelpyndyfeyfgpdfklhispsnmtnqntpeymekikqrlfe
nlrmlp

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6g3oC (C:)
ggkkkvcyyydgdignyyygqghpmkphrirmthnlllnyglyrkmeiyrphkataeemt
kyhsdeyikflrsirpdnmseyskqmqrfnvgedcpvfdglfefcqlstggsvagavkln
rqqtdmavnwagglhhakkseasgfcyvndivlailellkyhqrvlyididihhgdgvee
afyttdrvmtvsfhkygeyfpgtgdlrdigagkgkyyavnfpmrdgiddesygqifkpii
skvmemyqpsavvlqcgadslsgdrlgcfnltvkghakcvevvktfnlpllmlggggyti
rnvarcwtyetavaldceipnelpyndyfeyfgpdfklhispsnmtnqntpeymekikqr
lfenlrmlph

    Sequence, based on observed residues (ATOM records):
    >6g3oC (C:)
kkvcyyydgdignyyygqghpmkphrirmthnlllnyglyrkmeiyrphkataeemtkyh
sdeyikflrsirpdnmseyskqmqrfnvgedcpvfdglfefcqlstggsvagavklnrqq
tdmavnwagglhhakkseasgfcyvndivlailellkyhqrvlyididihhgdgveeafy
ttdrvmtvsfhkygeyfpgtgdlrdigagkgkyyavnfpmrdgiddesygqifkpiiskv
memyqpsavvlqcgadslsgdrlgcfnltvkghakcvevvktfnlpllmlggggytirnv
arcwtyetavaldceipnelpyndyfeyfgpdfklhispsnmtnqntpeymekikqrlfe
nlrmlp