PDB entry 6g32

View 6g32 on RCSB PDB site
Description: crystal structure of human geranylgeranyl diphosphate synthase mutant d188y
Deposited on 2018-03-24, released 2018-10-17
The last revision was dated 2018-11-07, with a file datestamp of 2018-11-02.
Experiment type: XRAY
Resolution: 3.28 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Geranylgeranyl pyrophosphate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: GGPS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O95749
      • conflict (115)
      • engineered mutation (194)
  • Chain 'B':
    Compound: Geranylgeranyl pyrophosphate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: GGPS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O95749
      • conflict (115)
      • engineered mutation (194)
  • Chain 'C':
    Compound: Geranylgeranyl pyrophosphate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: GGPS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O95749
      • conflict (115)
      • engineered mutation (194)
  • Chain 'D':
    Compound: Geranylgeranyl pyrophosphate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: GGPS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O95749
      • conflict (115)
      • engineered mutation (194)
  • Chain 'E':
    Compound: Geranylgeranyl pyrophosphate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: GGPS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O95749
      • conflict (115)
      • engineered mutation (194)
  • Chain 'F':
    Compound: Geranylgeranyl pyrophosphate synthase
    Species: Homo sapiens [TaxId:9606]
    Gene: GGPS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O95749
      • conflict (115)
      • engineered mutation (194)
  • Heterogens: GOL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6g32A (A:)
gsgsgsgmektqetvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievt
emlhnaslliddiednsklrrgfpvahsiygipsvinsanyvyflglekvltldhqdavk
lftrqllelhqgqgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedl
kpllntlglffqirydyanlhskeysenksfcedltegkfsfptihaiwsrpestqvqni
lrqrtenidikkycvhyledvgsfeytrntlkeleakaykqidarggnpelvalvkhlsk
mfkeene

    Sequence, based on observed residues (ATOM records):
    >6g32A (A:)
qetvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievtemlhnasllid
diednsklrrgfpvahsiygipsvinsanyvyflglekvltldhqdavklftrqllelhq
gqgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedlkpllntlglff
qirydyanlhsksfcedltegkfsfptihaiwsrpestqvqnilrqrtenidikkycvhy
ledvgsfeytrntlkeleakaykqidarggnpelvalvkhlskmfk

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6g32B (B:)
gsgsgsgmektqetvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievt
emlhnaslliddiednsklrrgfpvahsiygipsvinsanyvyflglekvltldhqdavk
lftrqllelhqgqgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedl
kpllntlglffqirydyanlhskeysenksfcedltegkfsfptihaiwsrpestqvqni
lrqrtenidikkycvhyledvgsfeytrntlkeleakaykqidarggnpelvalvkhlsk
mfkeene

    Sequence, based on observed residues (ATOM records):
    >6g32B (B:)
qetvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievtemlhnasllid
diednsklrrgfpvahsiygipsvinsanyvyflglekvltldhqdavklftrqllelhq
gqgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedlkpllntlglff
qirydyanlhssfcedltegkfsfptihaiwsrpestqvqnilrqrtenidikkycvhyl
edvgsfeytrntlkeleakaykqidarggnpelvalvkhlskmfk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6g32C (C:)
gsgsgsgmektqetvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievt
emlhnaslliddiednsklrrgfpvahsiygipsvinsanyvyflglekvltldhqdavk
lftrqllelhqgqgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedl
kpllntlglffqirydyanlhskeysenksfcedltegkfsfptihaiwsrpestqvqni
lrqrtenidikkycvhyledvgsfeytrntlkeleakaykqidarggnpelvalvkhlsk
mfkeene

    Sequence, based on observed residues (ATOM records):
    >6g32C (C:)
etvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievtemlhnasllidd
iednsklrrgfpvahsiygipsvinsanyvyflglekvltldhqdavklftrqllelhqg
qgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedlkpllntlglffq
irydyanlhsksfcedltegkfsfptihaiwsrpestqvqnilrqrtenidikkycvhyl
edvgsfeytrntlkeleakaykqidarggnpelvalvkhlskmfk

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6g32D (D:)
gsgsgsgmektqetvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievt
emlhnaslliddiednsklrrgfpvahsiygipsvinsanyvyflglekvltldhqdavk
lftrqllelhqgqgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedl
kpllntlglffqirydyanlhskeysenksfcedltegkfsfptihaiwsrpestqvqni
lrqrtenidikkycvhyledvgsfeytrntlkeleakaykqidarggnpelvalvkhlsk
mfkeene

    Sequence, based on observed residues (ATOM records):
    >6g32D (D:)
etvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievtemlhnasllidd
iednsklrrgfpvahsiygipsvinsanyvyflglekvltldhqdavklftrqllelhqg
qgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedlkpllntlglffq
irydyanlhssfcedltegkfsfptihaiwsrpestqvqnilrqrtenidikkycvhyle
dvgsfeytrntlkeleakaykqidarggnpelvalvkhlskmfk

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6g32E (E:)
gsgsgsgmektqetvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievt
emlhnaslliddiednsklrrgfpvahsiygipsvinsanyvyflglekvltldhqdavk
lftrqllelhqgqgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedl
kpllntlglffqirydyanlhskeysenksfcedltegkfsfptihaiwsrpestqvqni
lrqrtenidikkycvhyledvgsfeytrntlkeleakaykqidarggnpelvalvkhlsk
mfkeene

    Sequence, based on observed residues (ATOM records):
    >6g32E (E:)
qetvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievtemlhnasllid
diednsklrrgfpvahsiygipsvinsanyvyflglekvltldhqdavklftrqllelhq
gqgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedlkpllntlglff
qirydyanlhssfcedltegkfsfptihaiwsrpestqvqnilrqrtenidikkycvhyl
edvgsfeytrntlkeleakaykqidarggnpelvalvkhlskmf

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6g32F (F:)
gsgsgsgmektqetvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievt
emlhnaslliddiednsklrrgfpvahsiygipsvinsanyvyflglekvltldhqdavk
lftrqllelhqgqgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedl
kpllntlglffqirydyanlhskeysenksfcedltegkfsfptihaiwsrpestqvqni
lrqrtenidikkycvhyledvgsfeytrntlkeleakaykqidarggnpelvalvkhlsk
mfkeene

    Sequence, based on observed residues (ATOM records):
    >6g32F (F:)
qetvqrillepykyllqlpgkqvrtklsqafnhwlkvpedklqiiievtemlhnasllid
diednsklrrgfpvahsiygipsvinsanyvyflglekvltldhqdavklftrqllelhq
gqgldiywrdnytcpteeeykamvlqktgglfglavglmqlfsdykedlkpllntlglff
qirydyanlhsksfcedltegkfsfptihaiwsrpestqvqnilrqrtenidikkycvhy
ledvgsfeytrntlkeleakaykqidarggnpelvalvkhlskmf