PDB entry 6g2u

View 6g2u on RCSB PDB site
Description: Crystal structure of the human glutamate dehydrogenase 2 (hGDH2)
Class: oxidoreductase
Keywords: glutamate, dehydrogenase, OXIDOREDUCTASE
Deposited on 2018-03-23, released 2019-04-10
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-10, with a file datestamp of 2021-02-05.
Experiment type: XRAY
Resolution: 2.93 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate dehydrogenase 2, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GLUD2, GLUDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6g2ua1, d6g2ua2
  • Chain 'B':
    Compound: Glutamate dehydrogenase 2, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GLUD2, GLUDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6g2ub1, d6g2ub2
  • Chain 'C':
    Compound: Glutamate dehydrogenase 2, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GLUD2, GLUDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6g2uc1, d6g2uc2
  • Chain 'D':
    Compound: Glutamate dehydrogenase 2, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GLUD2, GLUDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6g2ud1, d6g2ud2
  • Chain 'E':
    Compound: Glutamate dehydrogenase 2, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GLUD2, GLUDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6g2ue1, d6g2ue2
  • Chain 'F':
    Compound: Glutamate dehydrogenase 2, mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: GLUD2, GLUDP1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6g2uf1, d6g2uf2
  • Heterogens: PO4, NA, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6g2uA (A:)
selvadreddpnffkmvegffdrgasivedklvkdlrtqeseeqkrnrvrgilriikpcn
hvlslsfpirrddgsweviegyraqhsqhrtpckggirystdvsvdevkalaslmtykca
vvdvpfggakagvkinpknytenelekitrrftmelakkgfigpgvdvpapdmntgerem
swiadtyastighydinahacvtgkpisqggihgrisatgrgvfhgienfineasymsil
gmtpgfrdktfvvqgfgnvglhsmrylhrfgakciavgesdgsiwnpdgidpkeledfkl
qhgsilgfpkakpyegsilevdcdilipaatekqltksnaprvkakiiaegangpttpea
dkiflernilvipdlylnaggvtvsyfewlknlnhvsygrltfkyerdsnyhlllsvqes
lerkfgkhggtipivptaefqdsisgasekdivhsalaytmersarqimhtamkynlgld
lrtaayvnaiekvfkvyseagvtft

    Sequence, based on observed residues (ATOM records): (download) 
    >6g2uA (A:)
eddpnffkmvegffdrgasivedklvkdlrtqeseeqkrnrvrgilriikpcnhvlslsf
pirrddgsweviegyraqhsqhrtpckggirystdvsvdevkalaslmtykcavvdvpfg
gakagvkinpknytenelekitrrftmelakkgfigpgvdvpapdmntgeremswiadty
astighydinahacvtgkpisqggihgrisatgrgvfhgienfineasymsilgmtpgfr
dktfvvqgfgnvglhsmrylhrfgakciavgesdgsiwnpdgidpkeledfklqhgsilg
fpkakpyegsilevdcdilipaatekqltksnaprvkakiiaegangpttpeadkifler
nilvipdlylnaggvtvsyfewlknlnhvsygrltfkyerdsnyhlllsvqeslerkfgk
hggtipivptaefqdsisgasekdivhsalaytmersarqimhtamkynlgldlrtaayv
naiekvfkvyseag

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6g2uB (B:)
selvadreddpnffkmvegffdrgasivedklvkdlrtqeseeqkrnrvrgilriikpcn
hvlslsfpirrddgsweviegyraqhsqhrtpckggirystdvsvdevkalaslmtykca
vvdvpfggakagvkinpknytenelekitrrftmelakkgfigpgvdvpapdmntgerem
swiadtyastighydinahacvtgkpisqggihgrisatgrgvfhgienfineasymsil
gmtpgfrdktfvvqgfgnvglhsmrylhrfgakciavgesdgsiwnpdgidpkeledfkl
qhgsilgfpkakpyegsilevdcdilipaatekqltksnaprvkakiiaegangpttpea
dkiflernilvipdlylnaggvtvsyfewlknlnhvsygrltfkyerdsnyhlllsvqes
lerkfgkhggtipivptaefqdsisgasekdivhsalaytmersarqimhtamkynlgld
lrtaayvnaiekvfkvyseagvtft

    Sequence, based on observed residues (ATOM records): (download) 
    >6g2uB (B:)
pnffkmvegffdrgasivedklvkdlrtqeseeqkrnrvrgilriikpcnhvlslsfpir
rddgsweviegyraqhsqhrtpckggirystdvsvdevkalaslmtykcavvdvpfggak
agvkinpknytenelekitrrftmelakkgfigpgvdvpapdmntgeremswiadtyast
ighydinahacvtgkpisqggihgrisatgrgvfhgienfineasymsilgmtpgfrdkt
fvvqgfgnvglhsmrylhrfgakciavgesdgsiwnpdgidpkeledfklqhgsilgfpk
akpyegsilevdcdilipaatekqltksnaprvkakiiaegangpttpeadkiflernil
vipdlylnaggvtvsyfewlknlnhvsygrltfkyerdsnyhlllsvqeslerkfgkhgg
tipivptaefqdsisgasekdivhsalaytmersarqimhtamkynlgldlrtaayvnai
ekvfkvyseag

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6g2uC (C:)
selvadreddpnffkmvegffdrgasivedklvkdlrtqeseeqkrnrvrgilriikpcn
hvlslsfpirrddgsweviegyraqhsqhrtpckggirystdvsvdevkalaslmtykca
vvdvpfggakagvkinpknytenelekitrrftmelakkgfigpgvdvpapdmntgerem
swiadtyastighydinahacvtgkpisqggihgrisatgrgvfhgienfineasymsil
gmtpgfrdktfvvqgfgnvglhsmrylhrfgakciavgesdgsiwnpdgidpkeledfkl
qhgsilgfpkakpyegsilevdcdilipaatekqltksnaprvkakiiaegangpttpea
dkiflernilvipdlylnaggvtvsyfewlknlnhvsygrltfkyerdsnyhlllsvqes
lerkfgkhggtipivptaefqdsisgasekdivhsalaytmersarqimhtamkynlgld
lrtaayvnaiekvfkvyseagvtft

    Sequence, based on observed residues (ATOM records): (download) 
    >6g2uC (C:)
pnffkmvegffdrgasivedklvkdlrtqeseeqkrnrvrgilriikpcnhvlslsfpir
rddgsweviegyraqhsqhrtpckggirystdvsvdevkalaslmtykcavvdvpfggak
agvkinpknytenelekitrrftmelakkgfigpgvdvpapdmntgeremswiadtyast
ighydinahacvtgkpisqggihgrisatgrgvfhgienfineasymsilgmtpgfrdkt
fvvqgfgnvglhsmrylhrfgakciavgesdgsiwnpdgidpkeledfklqhgsilgfpk
akpyegsilevdcdilipaatekqltksnaprvkakiiaegangpttpeadkiflernil
vipdlylnaggvtvsyfewlknlnhvsygrltfkyerdsnyhlllsvqeslerkfgkhgg
tipivptaefqdsisgasekdivhsalaytmersarqimhtamkynlgldlrtaayvnai
ekvfkvyseag

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6g2uD (D:)
selvadreddpnffkmvegffdrgasivedklvkdlrtqeseeqkrnrvrgilriikpcn
hvlslsfpirrddgsweviegyraqhsqhrtpckggirystdvsvdevkalaslmtykca
vvdvpfggakagvkinpknytenelekitrrftmelakkgfigpgvdvpapdmntgerem
swiadtyastighydinahacvtgkpisqggihgrisatgrgvfhgienfineasymsil
gmtpgfrdktfvvqgfgnvglhsmrylhrfgakciavgesdgsiwnpdgidpkeledfkl
qhgsilgfpkakpyegsilevdcdilipaatekqltksnaprvkakiiaegangpttpea
dkiflernilvipdlylnaggvtvsyfewlknlnhvsygrltfkyerdsnyhlllsvqes
lerkfgkhggtipivptaefqdsisgasekdivhsalaytmersarqimhtamkynlgld
lrtaayvnaiekvfkvyseagvtft

    Sequence, based on observed residues (ATOM records): (download) 
    >6g2uD (D:)
eddpnffkmvegffdrgasivedklvkdlrtqeseeqkrnrvrgilriikpcnhvlslsf
pirrddgsweviegyraqhsqhrtpckggirystdvsvdevkalaslmtykcavvdvpfg
gakagvkinpknytenelekitrrftmelakkgfigpgvdvpapdmntgeremswiadty
astighydinahacvtgkpisqggihgrisatgrgvfhgienfineasymsilgmtpgfr
dktfvvqgfgnvglhsmrylhrfgakciavgesdgsiwnpdgidpkeledfklqhgsilg
fpkakpyegsilevdcdilipaatekqltksnaprvkakiiaegangpttpeadkifler
nilvipdlylnaggvtvsyfewlknlnhvsygrltfkyerdsnyhlllsvqeslerkfgk
hggtipivptaefqdsisgasekdivhsalaytmersarqimhtamkynlgldlrtaayv
naiekvfkvyseagvt

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6g2uE (E:)
selvadreddpnffkmvegffdrgasivedklvkdlrtqeseeqkrnrvrgilriikpcn
hvlslsfpirrddgsweviegyraqhsqhrtpckggirystdvsvdevkalaslmtykca
vvdvpfggakagvkinpknytenelekitrrftmelakkgfigpgvdvpapdmntgerem
swiadtyastighydinahacvtgkpisqggihgrisatgrgvfhgienfineasymsil
gmtpgfrdktfvvqgfgnvglhsmrylhrfgakciavgesdgsiwnpdgidpkeledfkl
qhgsilgfpkakpyegsilevdcdilipaatekqltksnaprvkakiiaegangpttpea
dkiflernilvipdlylnaggvtvsyfewlknlnhvsygrltfkyerdsnyhlllsvqes
lerkfgkhggtipivptaefqdsisgasekdivhsalaytmersarqimhtamkynlgld
lrtaayvnaiekvfkvyseagvtft

    Sequence, based on observed residues (ATOM records): (download) 
    >6g2uE (E:)
dpnffkmvegffdrgasivedklvkdlrtqeseeqkrnrvrgilriikpcnhvlslsfpi
rrddgsweviegyraqhsqhrtpckggirystdvsvdevkalaslmtykcavvdvpfgga
kagvkinpknytenelekitrrftmelakkgfigpgvdvpapdmntgeremswiadtyas
tighydinahacvtgkpisqggihgrisatgrgvfhgienfineasymsilgmtpgfrdk
tfvvqgfgnvglhsmrylhrfgakciavgesdgsiwnpdgidpkeledfklqhgsilgfp
kakpyegsilevdcdilipaatekqltksnaprvkakiiaegangpttpeadkiflerni
lvipdlylnaggvtvsyfewlknlnhvsygrltfkyerdsnyhlllsvqeslerkfgkhg
gtipivptaefqdsisgasekdivhsalaytmersarqimhtamkynlgldlrtaayvna
iekvfkvyseag

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6g2uF (F:)
selvadreddpnffkmvegffdrgasivedklvkdlrtqeseeqkrnrvrgilriikpcn
hvlslsfpirrddgsweviegyraqhsqhrtpckggirystdvsvdevkalaslmtykca
vvdvpfggakagvkinpknytenelekitrrftmelakkgfigpgvdvpapdmntgerem
swiadtyastighydinahacvtgkpisqggihgrisatgrgvfhgienfineasymsil
gmtpgfrdktfvvqgfgnvglhsmrylhrfgakciavgesdgsiwnpdgidpkeledfkl
qhgsilgfpkakpyegsilevdcdilipaatekqltksnaprvkakiiaegangpttpea
dkiflernilvipdlylnaggvtvsyfewlknlnhvsygrltfkyerdsnyhlllsvqes
lerkfgkhggtipivptaefqdsisgasekdivhsalaytmersarqimhtamkynlgld
lrtaayvnaiekvfkvyseagvtft

    Sequence, based on observed residues (ATOM records): (download) 
    >6g2uF (F:)
eddpnffkmvegffdrgasivedklvkdlrtqeseeqkrnrvrgilriikpcnhvlslsf
pirrddgsweviegyraqhsqhrtpckggirystdvsvdevkalaslmtykcavvdvpfg
gakagvkinpknytenelekitrrftmelakkgfigpgvdvpapdmntgeremswiadty
astighydinahacvtgkpisqggihgrisatgrgvfhgienfineasymsilgmtpgfr
dktfvvqgfgnvglhsmrylhrfgakciavgesdgsiwnpdgidpkeledfklqhgsilg
fpkakpyegsilevdcdilipaatekqltksnaprvkakiiaegangpttpeadkifler
nilvipdlylnaggvtvsyfewlknlnhvsygrltfkyerdsnyhlllsvqeslerkfgk
hggtipivptaefqdsisgasekdivhsalaytmersarqimhtamkynlgldlrtaayv
naiekvfkvyseagvt