PDB entry 6g2t

View 6g2t on RCSB PDB site
Description: human cardiac myosin binding protein c c1 ig-domain bound to native cardiac thin filament
Deposited on 2018-03-23, released 2018-10-17
The last revision was dated 2018-12-19, with a file datestamp of 2018-12-14.
Experiment type: EM
Resolution: 9 Å
R-factor: N/A
AEROSPACI score: -0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Actin, cytoplasmic 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTG1, ACTG
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Actin, cytoplasmic 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTG1, ACTG
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Actin, cytoplasmic 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTG1, ACTG
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Actin, cytoplasmic 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTG1, ACTG
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Actin, cytoplasmic 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTG1, ACTG
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Actin, cytoplasmic 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ACTG1, ACTG
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Myosin-binding protein C, cardiac-type
    Species: Homo sapiens [TaxId:9606]
    Gene: MYBPC3
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: Myosin-binding protein C, cardiac-type
    Species: Homo sapiens [TaxId:9606]
    Gene: MYBPC3
    Database cross-references and differences (RAF-indexed):
  • Chain 'I':
    Compound: Myosin-binding protein C, cardiac-type
    Species: Homo sapiens [TaxId:9606]
    Gene: MYBPC3
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: Myosin-binding protein C, cardiac-type
    Species: Homo sapiens [TaxId:9606]
    Gene: MYBPC3
    Database cross-references and differences (RAF-indexed):
  • Chain 'K':
    Compound: Myosin-binding protein C, cardiac-type
    Species: Homo sapiens [TaxId:9606]
    Gene: MYBPC3
    Database cross-references and differences (RAF-indexed):
  • Chain 'L':
    Compound: Myosin-binding protein C, cardiac-type
    Species: Homo sapiens [TaxId:9606]
    Gene: MYBPC3
    Database cross-references and differences (RAF-indexed):
  • Chain 'M':
    Compound: tropomyosin
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • PDB 6G2T (0-134)
  • Chain 'N':
    Compound: tropomyosin
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • PDB 6G2T (0-134)
  • Chain 'O':
    Compound: tropomyosin
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • PDB 6G2T (0-134)
  • Chain 'P':
    Compound: tropomyosin
    Species: Sus scrofa [TaxId:9823]
    Database cross-references and differences (RAF-indexed):
    • PDB 6G2T (0-134)

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6g2tA (A:)
meeeiaalvidngsgmckagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
krgiltlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmt
qimfetfntpamyvaiqavlslyasgrttgivmdsgdgvthtvpiyegyalphailrldl
agrdltdylmkiltergysftttaereivrdikeklcyvaldfeqemataassssleksy
elpdgqvitignerfrcpealfqpsflgmescgihettfnsimkcdvdirkdlyantvls
ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwiskq
eydesgpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6g2tA (A:)
aalvidngsgmckagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgil
tlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmtqimfe
tfntpamyvaiqavlslyasgrttgivmdsgdgvthtvpiyegyalphailrldlagrdl
tdylmkiltergysftttaereivrdikeklcyvaldfeqemataassssleksyelpdg
qvitignerfrcpealfqpsflgmescgihettfnsimkcdvdirkdlyantvlsggttm
ypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwiskqeydes
gpsivhrkcf

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6g2tB (B:)
meeeiaalvidngsgmckagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
krgiltlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmt
qimfetfntpamyvaiqavlslyasgrttgivmdsgdgvthtvpiyegyalphailrldl
agrdltdylmkiltergysftttaereivrdikeklcyvaldfeqemataassssleksy
elpdgqvitignerfrcpealfqpsflgmescgihettfnsimkcdvdirkdlyantvls
ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwiskq
eydesgpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6g2tB (B:)
aalvidngsgmckagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgil
tlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmtqimfe
tfntpamyvaiqavlslyasgrttgivmdsgdgvthtvpiyegyalphailrldlagrdl
tdylmkiltergysftttaereivrdikeklcyvaldfeqemataassssleksyelpdg
qvitignerfrcpealfqpsflgmescgihettfnsimkcdvdirkdlyantvlsggttm
ypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwiskqeydes
gpsivhrkcf

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6g2tC (C:)
meeeiaalvidngsgmckagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
krgiltlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmt
qimfetfntpamyvaiqavlslyasgrttgivmdsgdgvthtvpiyegyalphailrldl
agrdltdylmkiltergysftttaereivrdikeklcyvaldfeqemataassssleksy
elpdgqvitignerfrcpealfqpsflgmescgihettfnsimkcdvdirkdlyantvls
ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwiskq
eydesgpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6g2tC (C:)
aalvidngsgmckagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgil
tlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmtqimfe
tfntpamyvaiqavlslyasgrttgivmdsgdgvthtvpiyegyalphailrldlagrdl
tdylmkiltergysftttaereivrdikeklcyvaldfeqemataassssleksyelpdg
qvitignerfrcpealfqpsflgmescgihettfnsimkcdvdirkdlyantvlsggttm
ypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwiskqeydes
gpsivhrkcf

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6g2tD (D:)
meeeiaalvidngsgmckagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
krgiltlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmt
qimfetfntpamyvaiqavlslyasgrttgivmdsgdgvthtvpiyegyalphailrldl
agrdltdylmkiltergysftttaereivrdikeklcyvaldfeqemataassssleksy
elpdgqvitignerfrcpealfqpsflgmescgihettfnsimkcdvdirkdlyantvls
ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwiskq
eydesgpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6g2tD (D:)
aalvidngsgmckagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgil
tlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmtqimfe
tfntpamyvaiqavlslyasgrttgivmdsgdgvthtvpiyegyalphailrldlagrdl
tdylmkiltergysftttaereivrdikeklcyvaldfeqemataassssleksyelpdg
qvitignerfrcpealfqpsflgmescgihettfnsimkcdvdirkdlyantvlsggttm
ypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwiskqeydes
gpsivhrkcf

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6g2tE (E:)
meeeiaalvidngsgmckagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
krgiltlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmt
qimfetfntpamyvaiqavlslyasgrttgivmdsgdgvthtvpiyegyalphailrldl
agrdltdylmkiltergysftttaereivrdikeklcyvaldfeqemataassssleksy
elpdgqvitignerfrcpealfqpsflgmescgihettfnsimkcdvdirkdlyantvls
ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwiskq
eydesgpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6g2tE (E:)
aalvidngsgmckagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgil
tlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmtqimfe
tfntpamyvaiqavlslyasgrttgivmdsgdgvthtvpiyegyalphailrldlagrdl
tdylmkiltergysftttaereivrdikeklcyvaldfeqemataassssleksyelpdg
qvitignerfrcpealfqpsflgmescgihettfnsimkcdvdirkdlyantvlsggttm
ypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwiskqeydes
gpsivhrkcf

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6g2tF (F:)
meeeiaalvidngsgmckagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
krgiltlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmt
qimfetfntpamyvaiqavlslyasgrttgivmdsgdgvthtvpiyegyalphailrldl
agrdltdylmkiltergysftttaereivrdikeklcyvaldfeqemataassssleksy
elpdgqvitignerfrcpealfqpsflgmescgihettfnsimkcdvdirkdlyantvls
ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwiskq
eydesgpsivhrkcf

    Sequence, based on observed residues (ATOM records):
    >6g2tF (F:)
aalvidngsgmckagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqskrgil
tlkypiehgivtnwddmekiwhhtfynelrvapeehpvllteaplnpkanrekmtqimfe
tfntpamyvaiqavlslyasgrttgivmdsgdgvthtvpiyegyalphailrldlagrdl
tdylmkiltergysftttaereivrdikeklcyvaldfeqemataassssleksyelpdg
qvitignerfrcpealfqpsflgmescgihettfnsimkcdvdirkdlyantvlsggttm
ypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwiskqeydes
gpsivhrkcf

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6g2tG (G:)
mddpiglfvmrpqdgevtvggsitfsarvagasllkppvvkwfkgkwvdlsskvgqhlql
hdsydraskvylfelhitdaqpaftgsyrcevstkdkfdcsnfnltvhe

    Sequence, based on observed residues (ATOM records):
    >6g2tG (G:)
ddpiglfvmrpqdgevtvggsitfsarvagkppvvkwfkgkwvdlsskvgqhlqlhdsyd
raskvylfelhitdaqpaftgsyrcevstkdkfdcsnfnltvhe

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6g2tH (H:)
mddpiglfvmrpqdgevtvggsitfsarvagasllkppvvkwfkgkwvdlsskvgqhlql
hdsydraskvylfelhitdaqpaftgsyrcevstkdkfdcsnfnltvhe

    Sequence, based on observed residues (ATOM records):
    >6g2tH (H:)
ddpiglfvmrpqdgevtvggsitfsarvagkppvvkwfkgkwvdlsskvgqhlqlhdsyd
raskvylfelhitdaqpaftgsyrcevstkdkfdcsnfnltvhe

  • Chain 'I':
    Sequence, based on SEQRES records:
    >6g2tI (I:)
mddpiglfvmrpqdgevtvggsitfsarvagasllkppvvkwfkgkwvdlsskvgqhlql
hdsydraskvylfelhitdaqpaftgsyrcevstkdkfdcsnfnltvhe

    Sequence, based on observed residues (ATOM records):
    >6g2tI (I:)
ddpiglfvmrpqdgevtvggsitfsarvagkppvvkwfkgkwvdlsskvgqhlqlhdsyd
raskvylfelhitdaqpaftgsyrcevstkdkfdcsnfnltvhe

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6g2tJ (J:)
mddpiglfvmrpqdgevtvggsitfsarvagasllkppvvkwfkgkwvdlsskvgqhlql
hdsydraskvylfelhitdaqpaftgsyrcevstkdkfdcsnfnltvhe

    Sequence, based on observed residues (ATOM records):
    >6g2tJ (J:)
ddpiglfvmrpqdgevtvggsitfsarvagkppvvkwfkgkwvdlsskvgqhlqlhdsyd
raskvylfelhitdaqpaftgsyrcevstkdkfdcsnfnltvhe

  • Chain 'K':
    Sequence, based on SEQRES records:
    >6g2tK (K:)
mddpiglfvmrpqdgevtvggsitfsarvagasllkppvvkwfkgkwvdlsskvgqhlql
hdsydraskvylfelhitdaqpaftgsyrcevstkdkfdcsnfnltvhe

    Sequence, based on observed residues (ATOM records):
    >6g2tK (K:)
ddpiglfvmrpqdgevtvggsitfsarvagkppvvkwfkgkwvdlsskvgqhlqlhdsyd
raskvylfelhitdaqpaftgsyrcevstkdkfdcsnfnltvhe

  • Chain 'L':
    Sequence, based on SEQRES records:
    >6g2tL (L:)
mddpiglfvmrpqdgevtvggsitfsarvagasllkppvvkwfkgkwvdlsskvgqhlql
hdsydraskvylfelhitdaqpaftgsyrcevstkdkfdcsnfnltvhe

    Sequence, based on observed residues (ATOM records):
    >6g2tL (L:)
ddpiglfvmrpqdgevtvggsitfsarvagkppvvkwfkgkwvdlsskvgqhlqlhdsyd
raskvylfelhitdaqpaftgsyrcevstkdkfdcsnfnltvhe

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records:
    >6g2tM (M:)
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxx

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records:
    >6g2tN (N:)
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxx

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records:
    >6g2tO (O:)
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxx

  • Chain 'P':
    Sequence; same for both SEQRES and ATOM records:
    >6g2tP (P:)
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
xxxxxxxxxxxxxxx