PDB entry 6g1w

View 6g1w on RCSB PDB site
Description: Crystal structure of Torpedo Californica acetylcholinesterase in complex with 2-{1-[2-(6-Chloro-1,2,3,4-tetrahydroacridin-9-ylamino)ethyl]-1H-1,2,3-triazol-4-yl}-N-[4-(hydroxy)-3-methoxybenzyl]acetamide
Class: hydrolase
Keywords: Torpedo Californica acetylcholinesterase, AD, alzheimer disease, HYDROLASE
Deposited on 2018-03-22, released 2018-04-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-04-04, with a file datestamp of 2018-03-29.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetylcholinesterase
    Species: Tetronarce californica [TaxId:7787]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6g1wa_
  • Chain 'B':
    Compound: acetylcholinesterase
    Species: Tetronarce californica [TaxId:7787]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6g1wb_
  • Heterogens: NAG, E0Z, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6g1wA (A:)
mnllvtsslgvllhlvvlcqaddhsellvntksgkvmgtrvpvlsshisaflgipfaepp
vgnmrfrrpepkkpwsgvwnastypnncqqyvdeqfpgfsgsemwnpnremsedclylni
wvpsprpksttvmvwiygggfysgsstldvyngkylayteevvlvslsyrvgafgflalh
gsqeapgnvglldqrmalqwvhdniqffggdpktvtifgesaggasvgmhilspgsrdlf
rrailqsgspncpwasvsvaegrrravelgrnlncnlnsdeelihclrekkpqelidvew
nvlpfdsifrfsfvpvidgeffptslesmlnsgnfkktqillgvnkdegsffllygapgf
skdseskisredfmsgvklsvphandlgldavtlqytdwmddnngiknrdglddivgdhn
vicplmhfvnkytkfgngtylyffnhrasnlvwpewmgvihgyeiefvfglplvkelnyt
aeeealsrrimhywatfaktgnpnephsqeskwplfttkeqkfidlntepmkvhqrlrvq
mcvfwnqflpkllnatacdgelsssgtssskgiifyvlfsilylif

    Sequence, based on observed residues (ATOM records): (download) 
    >6g1wA (A:)
sellvntksgkvmgtrvpvlsshisaflgipfaeppvgnmrfrrpepkkpwsgvwnasty
pnncqqyvdeqfpgfsgsemwnpnremsedclylniwvpsprpksttvmvwiygggfysg
sstldvyngkylayteevvlvslsyrvgafgflalhgsqeapgnvglldqrmalqwvhdn
iqffggdpktvtifgesaggasvgmhilspgsrdlfrrailqsgspncpwasvsvaegrr
ravelgrnlncnlnsdeelihclrekkpqelidvewnvlpfdsifrfsfvpvidgeffpt
slesmlnsgnfkktqillgvnkdegsffllygapgfskdseskisredfmsgvklsvpha
ndlgldavtlqytdwmddnngiknrdglddivgdhnvicplmhfvnkytkfgngtylyff
nhrasnlvwpewmgvihgyeiefvfglplvkelnytaeeealsrrimhywatfaktgnpn
ephsskwplfttkeqkfidlntepmkvhqrlrvqmcvfwnqflpkllnat

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6g1wB (B:)
mnllvtsslgvllhlvvlcqaddhsellvntksgkvmgtrvpvlsshisaflgipfaepp
vgnmrfrrpepkkpwsgvwnastypnncqqyvdeqfpgfsgsemwnpnremsedclylni
wvpsprpksttvmvwiygggfysgsstldvyngkylayteevvlvslsyrvgafgflalh
gsqeapgnvglldqrmalqwvhdniqffggdpktvtifgesaggasvgmhilspgsrdlf
rrailqsgspncpwasvsvaegrrravelgrnlncnlnsdeelihclrekkpqelidvew
nvlpfdsifrfsfvpvidgeffptslesmlnsgnfkktqillgvnkdegsffllygapgf
skdseskisredfmsgvklsvphandlgldavtlqytdwmddnngiknrdglddivgdhn
vicplmhfvnkytkfgngtylyffnhrasnlvwpewmgvihgyeiefvfglplvkelnyt
aeeealsrrimhywatfaktgnpnephsqeskwplfttkeqkfidlntepmkvhqrlrvq
mcvfwnqflpkllnatacdgelsssgtssskgiifyvlfsilylif

    Sequence, based on observed residues (ATOM records): (download) 
    >6g1wB (B:)
sellvntksgkvmgtrvpvlsshisaflgipfaeppvgnmrfrrpepkkpwsgvwnasty
pnncqqyvdeqfpgfsgsemwnpnremsedclylniwvpsprpksttvmvwiygggfysg
sstldvyngkylayteevvlvslsyrvgafgflalhgsqeapgnvglldqrmalqwvhdn
iqffggdpktvtifgesaggasvgmhilspgsrdlfrrailqsgspncpwasvsvaegrr
ravelgrnlncnlnsdeelihclrekkpqelidvewnvlpfdsifrfsfvpvidgeffpt
slesmlnsgnfkktqillgvnkdegsffllygapgfskdseskisredfmsgvklsvpha
ndlgldavtlqytdwmddnngiknrdglddivgdhnvicplmhfvnkytkfgngtylyff
nhrasnlvwpewmgvihgyeiefvfglplvkelnytaeeealsrrimhywatfaktgnpn
ephsqeskwplfttkeqkfidlntepmkvhqrlrvqmcvfwnqflpkllnat