PDB entry 6g1k

View 6g1k on RCSB PDB site
Description: electron cryo-microscopy structure of the canonical trpc4 ion channel
Deposited on 2018-03-21, released 2018-05-02
The last revision was dated 2018-08-01, with a file datestamp of 2018-07-27.
Experiment type: EM
Resolution: 3.6 Å
R-factor: N/A
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Transient receptor potential cation channel subfamily c member 4a
    Species: Danio rerio [TaxId:7955]
    Gene: trpc4b, trpc4a
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Transient receptor potential cation channel subfamily c member 4a
    Species: Danio rerio [TaxId:7955]
    Gene: trpc4b, trpc4a
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Transient receptor potential cation channel subfamily c member 4a
    Species: Danio rerio [TaxId:7955]
    Gene: trpc4b, trpc4a
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Transient receptor potential cation channel subfamily c member 4a
    Species: Danio rerio [TaxId:7955]
    Gene: trpc4b, trpc4a
    Database cross-references and differences (RAF-indexed):
  • Heterogens: Y01, 44E

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6g1kA (A:)
    gsqlyfrrtdnssyrdriplrivraeselstqeksylsavekgdyasvklaleeaeiyfk
    inincidplgrtalliaienenleiielllsfnvyvgdallhairkevvgavelllnhkk
    psgekqvppilldkqfsdftpditpiilaahtnnyeiikmlvqkgvsvpqphevrcncve
    cvsssdvdslrhsrsrlniykalaspslialssedpfltafqlswelqelskvenefkae
    yeelshqckhfakdlldqtrssrelelilnfrddmnllqdeannelarlklaikyrqkef
    vaqpncqqllasrwydefpgwrrrhwagklitcvfiglmfpllslcylvapksryglfir
    kpfikfichtasyltflfllllasqhivsnnpdrqgpkpttvewmilpwvlgfiwteikq
    mwdggfqdyihdwwnlmdfvmnslylatislkivayvkysgckprdtwemwhptlvaeav
    faianifsslrlislftanshlgplqislgrmlldilkflfiyclvllafanglnqlyfy
    yensegmtckgircerqnnafstlfetlqslfwsifglislyvtnvkadhkftefvgatm
    fgtynvislvvllnmliammnnsyqhiadhadiewkfartklwmsyfeeggtlpppfnii
    pspksicylitwikvhvfkrrskrtetfgtlgrraaenvrlnhqyqevlrnlvkryvaam
    irdakteeglteenfkelkqdissfryevigmmkgnrkstranksdtsasdvshpegslq
    yssalkqnsklhlydvttalqqqnseeakaslgclangsavvltepilkdkarsdfpkdf
    tdfglfpkkqnpnkiyslaeeatesdpdildwgkedkplagkveqdvneskclmeederv
    leeqemehiasshehlevlfq
    

    Sequence, based on observed residues (ATOM records):
    >6g1kA (A:)
    iplrivraeselstqeksylsavekgdyasvklaleeaeiyfkinincidplgrtallia
    ienenleiielllsfnvyvgdallhairkevvgavelllnhqfsdftpditpiilaahtn
    nyeiikmlvqkgvsvpqphvdslrhsrsrlniykalaspslialssedpfltafqlswel
    qelskvenefkaeyeelshqckhfakdlldqtrssrelelilnfrnelarlklaikyrqk
    efvaqpncqqllasrwydefprhwagklitcvfiglmfpllslcylvapksryglfirkp
    fikfichtasyltflfllllasqhivnpdrqgpkpttvewmilpwvlgfiwteikqmwdg
    gfqdyihdwwnlmdfvmnslylatislkivayvkysgckprdtwemwhptlvaeavfaia
    nifsslrlislftanshlgplqislgrmlldilkflfiyclvllafanglnqlyfyyens
    egmtckgircerqnnafstlfetlqslfwsifglislyvtnvkadhkftefvgatmfgty
    nvislvvllnmliammnnsyqhiadhadiewkfartklwmsyfetlpppfniiaenvrln
    hqyqevlrnlvkryvaamirdakteteenfkelkqdissfryevigmm
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6g1kB (B:)
    gsqlyfrrtdnssyrdriplrivraeselstqeksylsavekgdyasvklaleeaeiyfk
    inincidplgrtalliaienenleiielllsfnvyvgdallhairkevvgavelllnhkk
    psgekqvppilldkqfsdftpditpiilaahtnnyeiikmlvqkgvsvpqphevrcncve
    cvsssdvdslrhsrsrlniykalaspslialssedpfltafqlswelqelskvenefkae
    yeelshqckhfakdlldqtrssrelelilnfrddmnllqdeannelarlklaikyrqkef
    vaqpncqqllasrwydefpgwrrrhwagklitcvfiglmfpllslcylvapksryglfir
    kpfikfichtasyltflfllllasqhivsnnpdrqgpkpttvewmilpwvlgfiwteikq
    mwdggfqdyihdwwnlmdfvmnslylatislkivayvkysgckprdtwemwhptlvaeav
    faianifsslrlislftanshlgplqislgrmlldilkflfiyclvllafanglnqlyfy
    yensegmtckgircerqnnafstlfetlqslfwsifglislyvtnvkadhkftefvgatm
    fgtynvislvvllnmliammnnsyqhiadhadiewkfartklwmsyfeeggtlpppfnii
    pspksicylitwikvhvfkrrskrtetfgtlgrraaenvrlnhqyqevlrnlvkryvaam
    irdakteeglteenfkelkqdissfryevigmmkgnrkstranksdtsasdvshpegslq
    yssalkqnsklhlydvttalqqqnseeakaslgclangsavvltepilkdkarsdfpkdf
    tdfglfpkkqnpnkiyslaeeatesdpdildwgkedkplagkveqdvneskclmeederv
    leeqemehiasshehlevlfq
    

    Sequence, based on observed residues (ATOM records):
    >6g1kB (B:)
    iplrivraeselstqeksylsavekgdyasvklaleeaeiyfkinincidplgrtallia
    ienenleiielllsfnvyvgdallhairkevvgavelllnhqfsdftpditpiilaahtn
    nyeiikmlvqkgvsvpqphvdslrhsrsrlniykalaspslialssedpfltafqlswel
    qelskvenefkaeyeelshqckhfakdlldqtrssrelelilnfrnelarlklaikyrqk
    efvaqpncqqllasrwydefprhwagklitcvfiglmfpllslcylvapksryglfirkp
    fikfichtasyltflfllllasqhivnpdrqgpkpttvewmilpwvlgfiwteikqmwdg
    gfqdyihdwwnlmdfvmnslylatislkivayvkysgckprdtwemwhptlvaeavfaia
    nifsslrlislftanshlgplqislgrmlldilkflfiyclvllafanglnqlyfyyens
    egmtckgircerqnnafstlfetlqslfwsifglislyvtnvkadhkftefvgatmfgty
    nvislvvllnmliammnnsyqhiadhadiewkfartklwmsyfetlpppfniiaenvrln
    hqyqevlrnlvkryvaamirdakteteenfkelkqdissfryevigmm
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6g1kC (C:)
    gsqlyfrrtdnssyrdriplrivraeselstqeksylsavekgdyasvklaleeaeiyfk
    inincidplgrtalliaienenleiielllsfnvyvgdallhairkevvgavelllnhkk
    psgekqvppilldkqfsdftpditpiilaahtnnyeiikmlvqkgvsvpqphevrcncve
    cvsssdvdslrhsrsrlniykalaspslialssedpfltafqlswelqelskvenefkae
    yeelshqckhfakdlldqtrssrelelilnfrddmnllqdeannelarlklaikyrqkef
    vaqpncqqllasrwydefpgwrrrhwagklitcvfiglmfpllslcylvapksryglfir
    kpfikfichtasyltflfllllasqhivsnnpdrqgpkpttvewmilpwvlgfiwteikq
    mwdggfqdyihdwwnlmdfvmnslylatislkivayvkysgckprdtwemwhptlvaeav
    faianifsslrlislftanshlgplqislgrmlldilkflfiyclvllafanglnqlyfy
    yensegmtckgircerqnnafstlfetlqslfwsifglislyvtnvkadhkftefvgatm
    fgtynvislvvllnmliammnnsyqhiadhadiewkfartklwmsyfeeggtlpppfnii
    pspksicylitwikvhvfkrrskrtetfgtlgrraaenvrlnhqyqevlrnlvkryvaam
    irdakteeglteenfkelkqdissfryevigmmkgnrkstranksdtsasdvshpegslq
    yssalkqnsklhlydvttalqqqnseeakaslgclangsavvltepilkdkarsdfpkdf
    tdfglfpkkqnpnkiyslaeeatesdpdildwgkedkplagkveqdvneskclmeederv
    leeqemehiasshehlevlfq
    

    Sequence, based on observed residues (ATOM records):
    >6g1kC (C:)
    iplrivraeselstqeksylsavekgdyasvklaleeaeiyfkinincidplgrtallia
    ienenleiielllsfnvyvgdallhairkevvgavelllnhqfsdftpditpiilaahtn
    nyeiikmlvqkgvsvpqphvdslrhsrsrlniykalaspslialssedpfltafqlswel
    qelskvenefkaeyeelshqckhfakdlldqtrssrelelilnfrnelarlklaikyrqk
    efvaqpncqqllasrwydefprhwagklitcvfiglmfpllslcylvapksryglfirkp
    fikfichtasyltflfllllasqhivnpdrqgpkpttvewmilpwvlgfiwteikqmwdg
    gfqdyihdwwnlmdfvmnslylatislkivayvkysgckprdtwemwhptlvaeavfaia
    nifsslrlislftanshlgplqislgrmlldilkflfiyclvllafanglnqlyfyyens
    egmtckgircerqnnafstlfetlqslfwsifglislyvtnvkadhkftefvgatmfgty
    nvislvvllnmliammnnsyqhiadhadiewkfartklwmsyfetlpppfniiaenvrln
    hqyqevlrnlvkryvaamirdakteteenfkelkqdissfryevigmm
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6g1kD (D:)
    gsqlyfrrtdnssyrdriplrivraeselstqeksylsavekgdyasvklaleeaeiyfk
    inincidplgrtalliaienenleiielllsfnvyvgdallhairkevvgavelllnhkk
    psgekqvppilldkqfsdftpditpiilaahtnnyeiikmlvqkgvsvpqphevrcncve
    cvsssdvdslrhsrsrlniykalaspslialssedpfltafqlswelqelskvenefkae
    yeelshqckhfakdlldqtrssrelelilnfrddmnllqdeannelarlklaikyrqkef
    vaqpncqqllasrwydefpgwrrrhwagklitcvfiglmfpllslcylvapksryglfir
    kpfikfichtasyltflfllllasqhivsnnpdrqgpkpttvewmilpwvlgfiwteikq
    mwdggfqdyihdwwnlmdfvmnslylatislkivayvkysgckprdtwemwhptlvaeav
    faianifsslrlislftanshlgplqislgrmlldilkflfiyclvllafanglnqlyfy
    yensegmtckgircerqnnafstlfetlqslfwsifglislyvtnvkadhkftefvgatm
    fgtynvislvvllnmliammnnsyqhiadhadiewkfartklwmsyfeeggtlpppfnii
    pspksicylitwikvhvfkrrskrtetfgtlgrraaenvrlnhqyqevlrnlvkryvaam
    irdakteeglteenfkelkqdissfryevigmmkgnrkstranksdtsasdvshpegslq
    yssalkqnsklhlydvttalqqqnseeakaslgclangsavvltepilkdkarsdfpkdf
    tdfglfpkkqnpnkiyslaeeatesdpdildwgkedkplagkveqdvneskclmeederv
    leeqemehiasshehlevlfq
    

    Sequence, based on observed residues (ATOM records):
    >6g1kD (D:)
    iplrivraeselstqeksylsavekgdyasvklaleeaeiyfkinincidplgrtallia
    ienenleiielllsfnvyvgdallhairkevvgavelllnhqfsdftpditpiilaahtn
    nyeiikmlvqkgvsvpqphvdslrhsrsrlniykalaspslialssedpfltafqlswel
    qelskvenefkaeyeelshqckhfakdlldqtrssrelelilnfrnelarlklaikyrqk
    efvaqpncqqllasrwydefprhwagklitcvfiglmfpllslcylvapksryglfirkp
    fikfichtasyltflfllllasqhivnpdrqgpkpttvewmilpwvlgfiwteikqmwdg
    gfqdyihdwwnlmdfvmnslylatislkivayvkysgckprdtwemwhptlvaeavfaia
    nifsslrlislftanshlgplqislgrmlldilkflfiyclvllafanglnqlyfyyens
    egmtckgircerqnnafstlfetlqslfwsifglislyvtnvkadhkftefvgatmfgty
    nvislvvllnmliammnnsyqhiadhadiewkfartklwmsyfetlpppfniiaenvrln
    hqyqevlrnlvkryvaamirdakteteenfkelkqdissfryevigmm