PDB entry 6g0r

View 6g0r on RCSB PDB site
Description: crystal structure of the first bromodomain of human brd4 in complex with an acetylated polr2a peptide (k775ac/k778ac)
Deposited on 2018-03-19, released 2018-11-28
The last revision was dated 2019-02-20, with a file datestamp of 2019-02-15.
Experiment type: XRAY
Resolution: 1.25 Å
R-factor: N/A
AEROSPACI score: 0.63 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD4, HUNK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60885 (0-126)
      • conflict (1)
  • Chain 'C':
    Compound: DNA-directed RNA polymerase II subunit RPB1
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: ALY, EDO, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records:
    >6g0rA (A:)
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6g0rC (C:)
sgakgskiniy

    Sequence, based on observed residues (ATOM records):
    >6g0rC (C:)
gakgskin