PDB entry 6g05

View 6g05 on RCSB PDB site
Description: rorgt (264-518;c455s) in complex with inverse agonist "cpd-2" and rip140 peptide at 1.90a
Class: transcription
Keywords: fbs, nuclear hormone receptor, ligand-binding domain, inverse agonist, signaling protein, transcription
Deposited on 2018-03-16, released 2018-07-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-08-22, with a file datestamp of 2018-08-17.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Nuclear receptor ROR-gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: RORC, NR1F3, RORG, RZRG
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51449
      • engineered mutation (193)
    Domains in SCOPe 2.08: d6g05a_
  • Chain 'B':
    Compound: Nuclear receptor ROR-gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: RORC, NR1F3, RORG, RZRG
    Database cross-references and differences (RAF-indexed):
    • Uniprot P51449
      • engineered mutation (193)
    Domains in SCOPe 2.08: d6g05b_
  • Chain 'P':
    Compound: Nuclear receptor-interacting protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: Nuclear receptor-interacting protein 1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: EF5, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6g05A (A:)
gpyaslteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemwerca
hhlteaiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvffegk
yggmelfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekrkveq
lqynlelafhhhlskthrqsilaklppkgklrslcsqhverlqifqhlhpivvqaafppl
ykelfstetespvglsk

    Sequence, based on observed residues (ATOM records): (download) 
    >6g05A (A:)
yaslteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemwercahh
lteaiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvffegkyg
gmelfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekrkveqlq
ynlelafhhhlskthrqsilaklppkgklrslcsqhverlqifqhlhpivvqaafpplyk
elfst

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6g05B (B:)
gpyaslteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemwerca
hhlteaiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvffegk
yggmelfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekrkveq
lqynlelafhhhlskthrqsilaklppkgklrslcsqhverlqifqhlhpivvqaafppl
ykelfstetespvglsk

    Sequence, based on observed residues (ATOM records): (download) 
    >6g05B (B:)
yaslteiehlvqsvcksyretcqlrledllrqrsnifsreevtgyqrksmwemwercahh
lteaiqyvvefakrlsgfmelcqndqivllkagamevvlvrmcraynadnrtvffegkyg
gmelfralgcselissifdfshslsalhfsedeialytalvlinahrpglqekrkveqlq
ynlelafhhhlskthrqsilaklppkgklrslcsqhverlqifqhlhpivvqaafpplyk
elfst

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    No sequence available.