PDB entry 6fzj

View 6fzj on RCSB PDB site
Description: ppar gamma mutant complex
Deposited on 2018-03-14, released 2019-02-13
The last revision was dated 2019-02-13, with a file datestamp of 2019-02-08.
Experiment type: XRAY
Resolution: 2.01 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARG, NR1C3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37231 (Start-274)
      • engineered mutation (49)
  • Chain 'B':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARG, NR1C3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37231 (Start-274)
      • engineered mutation (49)
  • Chain 'C':
    Compound: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6FZJ (Start-13)
  • Chain 'D':
    Compound: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6FZJ (Start-13)
  • Heterogens: EDK, IOD, CL, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6fzjA (A:)
qlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydinslmmgedki
kfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygv
heiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldds
dlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdl
rqivtehvqllqvikktetdmslhpllqeiykdly

    Sequence, based on observed residues (ATOM records):
    >6fzjA (A:)
adlralakhlydsyiksfpltkakarailtgkttdkspfviydinslmmgedkikfkhit
peqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiytml
aslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaifiav
iilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivtehv
qllqvikktetdmslhpllqeiykdly

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6fzjB (B:)
qlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydinslmmgedki
kfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygv
heiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldds
dlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdl
rqivtehvqllqvikktetdmslhpllqeiykdly

    Sequence, based on observed residues (ATOM records):
    >6fzjB (B:)
npesadlralakhlydsyiksfpltkakarailtgkttdkspfviydinslmmgedkikf
khitplqkevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheiiy
tmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlaif
iaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqivt
ehvqllqvikktetdmslhpllqeiykdly

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6fzjC (C:)
eepsllkklllapa

    Sequence, based on observed residues (ATOM records):
    >6fzjC (C:)
psllkklllapa

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6fzjD (D:)
eepsllkklllapa

    Sequence, based on observed residues (ATOM records):
    >6fzjD (D:)
psllkklllapa