PDB entry 6fzf

View 6fzf on RCSB PDB site
Description: ppar mutant complex
Deposited on 2018-03-14, released 2019-02-13
The last revision was dated 2019-02-13, with a file datestamp of 2019-02-08.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARG, NR1C3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37231 (Start-278)
      • engineered mutation (248)
  • Chain 'B':
    Compound: Peroxisome proliferator-activated receptor gamma
    Species: Homo sapiens [TaxId:9606]
    Gene: PPARG, NR1C3
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37231 (4-278)
      • engineered mutation (248)
  • Chain 'C':
    Compound: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Peroxisome proliferator-activated receptor gamma coactivator 1-alpha
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: EDK, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6fzfA (A:)
    gshmqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmg
    edkikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtll
    kygvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnale
    lddsdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqk
    mtdlrqivmehvqllqvikktetdmslhpllqeiykdly
    

    Sequence, based on observed residues (ATOM records):
    >6fzfA (A:)
    esadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedkikfkh
    itplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygvheii
    ytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnalelddsdlai
    fiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdlrqiv
    mehvqllqvikktetdmslhpllqeiykdly
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6fzfB (B:)
    gshmqlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmg
    edkikfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtll
    kygvheiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnale
    lddsdlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqk
    mtdlrqivmehvqllqvikktetdmslhpllqeiykdly
    

    Sequence, based on observed residues (ATOM records):
    >6fzfB (B:)
    qlnpesadlralakhlydsyiksfpltkakarailtgkttdkspfviydmnslmmgedki
    kfkhitplqeqskevairifqgcqfrsveavqeiteyaksipgfvnldlndqvtllkygv
    heiiytmlaslmnkdgvlisegqgfmtreflkslrkpfgdfmepkfefavkfnaleldds
    dlaifiaviilsgdrpgllnvkpiediqdnllqalelqlklnhpessqlfakllqkmtdl
    rqivmehvqllqvikktetdmslhpllqeiykdly
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6fzfC (C:)
    eepsllkklllapa
    

    Sequence, based on observed residues (ATOM records):
    >6fzfC (C:)
    epsllkklllapa
    

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6fzfD (D:)
    eepsllkklllapa
    

    Sequence, based on observed residues (ATOM records):
    >6fzfD (D:)
    epsllkklllapa