PDB entry 6fyk

View 6fyk on RCSB PDB site
Description: X-Ray structure of CLK2-KD(136-496)/Indazole1 at 2.39A
Class: transferase
Keywords: splicing, phosphotransferase, transferase
Deposited on 2018-03-12, released 2018-07-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-07-18, with a file datestamp of 2018-07-13.
Experiment type: XRAY
Resolution: 2.39 Å
R-factor: N/A
AEROSPACI score: 0.23 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity protein kinase CLK2
    Species: Homo sapiens [TaxId:9606]
    Gene: CLK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6fyka_
  • Chain 'B':
    Compound: Dual specificity protein kinase CLK2
    Species: Homo sapiens [TaxId:9606]
    Gene: CLK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6fykb_
  • Chain 'C':
    Compound: Dual specificity protein kinase CLK2
    Species: Homo sapiens [TaxId:9606]
    Gene: CLK2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6fykc_
  • Heterogens: EAZ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fykA (A:)
gpssrraksveddaeghliyhvgdwlqeryeivstlgegtfgrvvqcvdhrrggarvalk
iiknvekykeaarleinvlekinekdpdnknlcvqmfdwfdyhghmcisfellglstfdf
lkdnnylpypihqvrhmafqlcqavkflhdnklthtdlkpenilfvnsdyeltynlekkr
dersvkstavrvvdfgsatfdhehhstivstrhyrapevilelgwsqpcdvwsigciife
yyvgftlfqthdnrehlammerilgpipsrmirktrkqkyfyrgrldwdentsagryvre
nckplrryltseaeehhqlfdliesmleyepakrltlgealqhpffarlraeppnklwds
srd

    Sequence, based on observed residues (ATOM records): (download) 
    >6fykA (A:)
srraksveddaeghliyhvgdwlqeryeivstlgegtfgrvvqcvdhrrggarvalkiik
nvekykeaarleinvlekinekdpdnknlcvqmfdwfdyhghmcisfellglstfdflkd
nnylpypihqvrhmafqlcqavkflhdnklthtdlkpenilfvnsdyeltynlekkrder
svkstavrvvdfgsatfdhehhstivstrhyrapevilelgwsqpcdvwsigciifeyyv
gftlfqthdnrehlammerilgpipsrmirktrkqkyfyrgrldwdentsagryvrenck
plrryltseaeehhqlfdliesmleyepakrltlgealqhpffarlrae

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6fykB (B:)
gpssrraksveddaeghliyhvgdwlqeryeivstlgegtfgrvvqcvdhrrggarvalk
iiknvekykeaarleinvlekinekdpdnknlcvqmfdwfdyhghmcisfellglstfdf
lkdnnylpypihqvrhmafqlcqavkflhdnklthtdlkpenilfvnsdyeltynlekkr
dersvkstavrvvdfgsatfdhehhstivstrhyrapevilelgwsqpcdvwsigciife
yyvgftlfqthdnrehlammerilgpipsrmirktrkqkyfyrgrldwdentsagryvre
nckplrryltseaeehhqlfdliesmleyepakrltlgealqhpffarlraeppnklwds
srd

    Sequence, based on observed residues (ATOM records): (download) 
    >6fykB (B:)
srraksveddaeghliyhvgdwlqeryeivstlgegtfgrvvqcvdhrrggarvalkiik
nvekykeaarleinvlekinekdpdnknlcvqmfdwfdyhghmcisfellglstfdflkd
nnylpypihqvrhmafqlcqavkflhdnklthtdlkpenilfvnsdyeltynlekkrder
svkstavrvvdfgsatfdhehhstivstrhyrapevilelgwsqpcdvwsigciifeyyv
gftlfqthdnrehlammerilgpipsrmirktrkqkyfyrgrldwdentsagryvrenck
plrryltseaeehhqlfdliesmleyepakrltlgealqhpffarlrae

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6fykC (C:)
gpssrraksveddaeghliyhvgdwlqeryeivstlgegtfgrvvqcvdhrrggarvalk
iiknvekykeaarleinvlekinekdpdnknlcvqmfdwfdyhghmcisfellglstfdf
lkdnnylpypihqvrhmafqlcqavkflhdnklthtdlkpenilfvnsdyeltynlekkr
dersvkstavrvvdfgsatfdhehhstivstrhyrapevilelgwsqpcdvwsigciife
yyvgftlfqthdnrehlammerilgpipsrmirktrkqkyfyrgrldwdentsagryvre
nckplrryltseaeehhqlfdliesmleyepakrltlgealqhpffarlraeppnklwds
srd

    Sequence, based on observed residues (ATOM records): (download) 
    >6fykC (C:)
srraksveddaeghliyhvgdwlqeryeivstlgegtfgrvvqcvdhrrggarvalkiik
nvekykeaarleinvlekinekdpdnknlcvqmfdwfdyhghmcisfellglstfdflkd
nnylpypihqvrhmafqlcqavkflhdnklthtdlkpenilfvnsdyeltynlekkrder
svkstavrvvdfgsatfdhehhstivstrhyrapevilelgwsqpcdvwsigciifeyyv
gftlfqthdnrehlammerilgpipsrmirktrkqkyfyrgrldwdentsagryvrenck
plrryltseaeehhqlfdliesmleyepakrltlgealqhpffarlrae