PDB entry 6fy4

View 6fy4 on RCSB PDB site
Description: Structure of human NAD(P) H:quinone oxidoreductase in complex with N-(2-bromophenyl)pyrrolidine-1-sulfonamide
Class: oxidoreductase
Keywords: flavoprotein ligand complex quinone reduction oxidative stress drug metabolism, OXIDOREDUCTASE
Deposited on 2018-03-10, released 2019-03-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2019-03-20, with a file datestamp of 2019-03-15.
Experiment type: XRAY
Resolution: 2.76 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: nad(p)h dehydrogenase [quinone] 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NQO1, DIA4, NMOR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6fy4a_
  • Chain 'B':
    Compound: nad(p)h dehydrogenase [quinone] 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NQO1, DIA4, NMOR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6fy4b_
  • Chain 'C':
    Compound: nad(p)h dehydrogenase [quinone] 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NQO1, DIA4, NMOR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6fy4c_
  • Chain 'D':
    Compound: nad(p)h dehydrogenase [quinone] 1
    Species: Homo sapiens [TaxId:9606]
    Gene: NQO1, DIA4, NMOR1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6fy4d_
  • Heterogens: FAD, EAW

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6fy4A (A:)
    mvgrralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgkl
    kdpanfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwferv
    figefaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfc
    gfqvlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmk
    kevqdeeknkkfglsvghhlgksiptdnqikark
    

    Sequence, based on observed residues (ATOM records): (download)
    >6fy4A (A:)
    rralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgklkdp
    anfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwfervfig
    efaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfcgfq
    vlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmkkev
    qdeeknkkfglsvghhlgksiptdnqikar
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6fy4B (B:)
    mvgrralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgkl
    kdpanfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwferv
    figefaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfc
    gfqvlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmk
    kevqdeeknkkfglsvghhlgksiptdnqikark
    

    Sequence, based on observed residues (ATOM records): (download)
    >6fy4B (B:)
    rralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgklkdp
    anfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwfervfig
    efaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfcgfq
    vlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmkkev
    qdeeknkkfglsvghhlgksiptdnqikar
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >6fy4C (C:)
    mvgrralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgkl
    kdpanfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwferv
    figefaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfc
    gfqvlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmk
    kevqdeeknkkfglsvghhlgksiptdnqikark
    

    Sequence, based on observed residues (ATOM records): (download)
    >6fy4C (C:)
    rralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgklkdp
    anfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwfervfig
    efaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfcgfq
    vlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmkkev
    qdeeknkkfglsvghhlgksiptdnqikar
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >6fy4D (D:)
    mvgrralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgkl
    kdpanfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwferv
    figefaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfc
    gfqvlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmk
    kevqdeeknkkfglsvghhlgksiptdnqikark
    

    Sequence, based on observed residues (ATOM records): (download)
    >6fy4D (D:)
    rralivlahsertsfnyamkeaaaaalkkkgwevvesdlyamnfnpiisrkditgklkdp
    anfqypaesvlaykeghlspdivaeqkkleaadlvifqfplqwfgvpailkgwfervfig
    efaytyaamydkgpfrskkavlsittggsgsmyslqgihgdmnvilwpiqsgilhfcgfq
    vlepqltysightpadariqilegwkkrleniwdetplyfapsslfdlnfqagflmkkev
    qdeeknkkfglsvghhlgksiptdnqikar