PDB entry 6fxu
View 6fxu on RCSB PDB site
Description: Crystal structure of human transthyretin mutant T119M at pH 5.5
Class: transport protein
Keywords: Amyloid, Gatekeeper, Aggregation, Stability, TRANSPORT PROTEIN
Deposited on
2018-03-09, released
2019-03-20
The last revision prior to the SCOPe 2.08 freeze date was dated
2019-03-20, with a file datestamp of
2019-03-15.
Experiment type: XRAY
Resolution: 1.36 Å
R-factor: N/A
AEROSPACI score: 0.56
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
- Uniprot P02766
- engineered mutation (118)
Domains in SCOPe 2.08: d6fxua_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
- Uniprot P02766
- engineered mutation (118)
Domains in SCOPe 2.08: d6fxub_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6fxuA (A:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystma
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>6fxuA (A:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsgprrytiaallspysystmavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6fxuB (B:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprrytiaallspysystma
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>6fxuB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsrrytiaallspysystmavvtnp