PDB entry 6fwb

View 6fwb on RCSB PDB site
Description: Crystal structure of Mat2A at 1.79 Angstron resolution
Class: hydrolase
Keywords: S-adenosylmethionine synthetase 2, HYDROLASE
Deposited on 2018-03-06, released 2019-03-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-06-12, with a file datestamp of 2019-06-07.
Experiment type: XRAY
Resolution: 1.79 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fwba1, d6fwba2, d6fwba3
  • Chain 'B':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fwbb1, d6fwbb2, d6fwbb3
  • Chain 'C':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fwbc1, d6fwbc2, d6fwbc3
  • Chain 'D':
    Compound: S-adenosylmethionine synthase isoform type-2
    Species: Homo sapiens [TaxId:9606]
    Gene: MAT2A, AMS2, MATA2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fwbd1, d6fwbd2, d6fwbd3
  • Heterogens: SO4, PG4, NA, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fwbA (A:)
mahhhhhhenlyfqgsmngqlngfheafieegtflftsesvgeghpdkicdqisdavlda
hlqqdpdakvacetvaktgmillageitsraavdyqkvvreavkhigyddsskgfdyktc
nvlvaleqqspdiaqgvhldrneedigagdqglmfgyatdeteecmpltivlahklnakl
aelrrngtlpwlrpdsktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrdalke
kvikavvpakyldedtiyhlqpsgrfviggpqgdagltgrkiivdtyggwgahgggafsg
kdytkvdrsaayaarwvakslvkgglcrrvlvqvsyaigvshplsisifhygtsqksere
lleivkknfdlrpgvivrdldlkkpiyqrtaayghfgrdsfpwevpkklk

    Sequence, based on observed residues (ATOM records): (download) 
    >6fwbA (A:)
gtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageitsra
avdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspeedigagdqglmfgyatdet
eecmpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrgavlpirvhtivis
vqhdeevcldemrdalkekvikavvpakyldedtiyhlqpsgrfviggpqgdagltgrki
ivdtyggwgahgggafsgkdytkvdrsaayaarwvakslvkgglcrrvlvqvsyaigvsh
plsisifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqrtaayghfgrdsfp
wevpkklk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6fwbB (B:)
mahhhhhhenlyfqgsmngqlngfheafieegtflftsesvgeghpdkicdqisdavlda
hlqqdpdakvacetvaktgmillageitsraavdyqkvvreavkhigyddsskgfdyktc
nvlvaleqqspdiaqgvhldrneedigagdqglmfgyatdeteecmpltivlahklnakl
aelrrngtlpwlrpdsktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrdalke
kvikavvpakyldedtiyhlqpsgrfviggpqgdagltgrkiivdtyggwgahgggafsg
kdytkvdrsaayaarwvakslvkgglcrrvlvqvsyaigvshplsisifhygtsqksere
lleivkknfdlrpgvivrdldlkkpiyqrtaayghfgrdsfpwevpkklk

    Sequence, based on observed residues (ATOM records): (download) 
    >6fwbB (B:)
ieegtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageit
sraavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspdneedigagdqglmfgy
atdeteecmpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrgavlpirvh
tivisvqhdeevcldemrdalkekvikavvpakyldedtiyhlqpsgrfviggpqgdagl
tgrkiivdtyggwgahgggafsgkdytkvdrsaayaarwvakslvkgglcrrvlvqvsya
igvshplsisifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqrtaayghfg
rdsfpwevpkklk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6fwbC (C:)
mahhhhhhenlyfqgsmngqlngfheafieegtflftsesvgeghpdkicdqisdavlda
hlqqdpdakvacetvaktgmillageitsraavdyqkvvreavkhigyddsskgfdyktc
nvlvaleqqspdiaqgvhldrneedigagdqglmfgyatdeteecmpltivlahklnakl
aelrrngtlpwlrpdsktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrdalke
kvikavvpakyldedtiyhlqpsgrfviggpqgdagltgrkiivdtyggwgahgggafsg
kdytkvdrsaayaarwvakslvkgglcrrvlvqvsyaigvshplsisifhygtsqksere
lleivkknfdlrpgvivrdldlkkpiyqrtaayghfgrdsfpwevpkklk

    Sequence, based on observed residues (ATOM records): (download) 
    >6fwbC (C:)
egtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageitsr
aavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqspgagdqglmfgyatdeteec
mpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrgavlpirvhtivisvqh
deevcldemrdalkekvikavvpakyldedtiyhlqpsgrfviggpqgdagltgrkiivd
tyggwgahgggafsgkdytkvdrsaayaarwvakslvkgglcrrvlvqvsyaigvshpls
isifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqrtaayghfgrdsfpwev
pkkl

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6fwbD (D:)
mahhhhhhenlyfqgsmngqlngfheafieegtflftsesvgeghpdkicdqisdavlda
hlqqdpdakvacetvaktgmillageitsraavdyqkvvreavkhigyddsskgfdyktc
nvlvaleqqspdiaqgvhldrneedigagdqglmfgyatdeteecmpltivlahklnakl
aelrrngtlpwlrpdsktqvtvqymqdrgavlpirvhtivisvqhdeevcldemrdalke
kvikavvpakyldedtiyhlqpsgrfviggpqgdagltgrkiivdtyggwgahgggafsg
kdytkvdrsaayaarwvakslvkgglcrrvlvqvsyaigvshplsisifhygtsqksere
lleivkknfdlrpgvivrdldlkkpiyqrtaayghfgrdsfpwevpkklk

    Sequence, based on observed residues (ATOM records): (download) 
    >6fwbD (D:)
egtflftsesvgeghpdkicdqisdavldahlqqdpdakvacetvaktgmillageitsr
aavdyqkvvreavkhigyddsskgfdyktcnvlvaleqqeedigagdqglmfgyatdete
ecmpltivlahklnaklaelrrngtlpwlrpdsktqvtvqymqdrgavlpirvhtivisv
qhdeevcldemrdalkekvikavvpakyldedtiyhlqpsgrfviggpqgdagltgrkii
vdtyggwgahgggafsgkdytkvdrsaayaarwvakslvkgglcrrvlvqvsyaigvshp
lsisifhygtsqkserelleivkknfdlrpgvivrdldlkkpiyqrtaayghfgrdsfpw
evpkklk