PDB entry 6fvz

View 6fvz on RCSB PDB site
Description: Crystal structure of human monoamine oxidase B (MAO B) in complex with dimethylphenyl-chromone-carboxamide
Class: flavoprotein
Keywords: Parkinson's disease, drug design, chromone, inhibitor, FLAVOPROTEIN
Deposited on 2018-03-05, released 2018-04-25
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-04-25, with a file datestamp of 2018-04-20.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: amine oxidase [flavin-containing] b
    Species: Homo sapiens [TaxId:9606]
    Gene: MAOB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6fvza1, d6fvza2
  • Chain 'B':
    Compound: amine oxidase [flavin-containing] b
    Species: Homo sapiens [TaxId:9606]
    Gene: MAOB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6fvzb1, d6fvzb2
  • Heterogens: FAD, E8Z, C15, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fvzA (A:)
msnkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsy
vgptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwr
tmddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethev
salwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidq
trenvlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvplgsvikcivy
ykepfwrkkdycgtmiidgeeapvaytlddtkpegnyaaimgfilahkarklarltkeer
lkklcelyakvlgslealepvhyeeknwceeqysggcyttyfppgiltqygrvlrqpvdr
iyfagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvpaqpittt
flerhlpsvpgllrliglttifsatalgflahkrgllvrv

    Sequence, based on observed residues (ATOM records): (download) 
    >6fvzA (A:)
snkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsyv
gptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwrt
mddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethevs
alwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidqt
renvlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvplgsvikcivyy
kepfwrkkdycgtmiidgeeapvaytlddtkpegnyaaimgfilahkarklarltkeerl
kklcelyakvlgslealepvhyeeknwceeqysggcyttyfppgiltqygrvlrqpvdri
yfagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvpaqpitttf
lerhlpsvpgllrligltti

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6fvzB (B:)
msnkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsy
vgptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwr
tmddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethev
salwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidq
trenvlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvplgsvikcivy
ykepfwrkkdycgtmiidgeeapvaytlddtkpegnyaaimgfilahkarklarltkeer
lkklcelyakvlgslealepvhyeeknwceeqysggcyttyfppgiltqygrvlrqpvdr
iyfagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvpaqpittt
flerhlpsvpgllrliglttifsatalgflahkrgllvrv

    Sequence, based on observed residues (ATOM records): (download) 
    >6fvzB (B:)
snkcdvvvvgggisgmaaakllhdsglnvvvleardrvggrtytlrnqkvkyvdlggsyv
gptqnrilrlakelgletykvneverlihhvkgksypfrgpfppvwnpityldhnnfwrt
mddmgreipsdapwkaplaeewdnmtmkelldklcwtesakqlatlfvnlcvtaethevs
alwflwyvkqcggttriisttnggqerkfvggsgqvserimdllgdrvklerpviyidqt
renvlvetlnhemyeakyvisaipptlgmkihfnpplpmmrnqmitrvplgsvikcivyy
kepfwrkkdycgtmiidgeeapvaytlddtkpegnyaaimgfilahkarklarltkeerl
kklcelyakvlgslealepvhyeeknwceeqysggcyttyfppgiltqygrvlrqpvdri
yfagtetathwsgymegaveageraareilhamgkipedeiwqsepesvdvpaqpitttf
lerhlpsvpgllrli