PDB entry 6fu5

View 6fu5 on RCSB PDB site
Description: structure of the kinase domain of human ripk2 in complex with the inhibitor cslp18
Deposited on 2018-02-26, released 2018-04-25
The last revision was dated 2018-09-12, with a file datestamp of 2018-09-07.
Experiment type: XRAY
Resolution: 3.26 Å
R-factor: N/A
AEROSPACI score: 0.11 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: receptor-interacting serine/threonine-protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RIPK2, CARDIAK, RICK, RIP2, UNQ277/PRO314/PRO34092
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: receptor-interacting serine/threonine-protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: RIPK2, CARDIAK, RICK, RIP2, UNQ277/PRO314/PRO34092
    Database cross-references and differences (RAF-indexed):
  • Heterogens: E7N, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6fu5A (A:)
smgeaicsalptipyhkladlrylsrgasgtvssarhadwrvqvavkhlhihtplldser
kdvlreaeilhkarfsyilpilgicnepeflgivteympngslnellhrkteypdvawpl
rfrilheialgvnylhnmtppllhhdlktqnilldnefhvkiadfglskwrmmslsqsrs
sksapeggtiiymppenyepgqksrasikhdiysyavitwevlsrkqpfedvtnplqimy
svsqghrpvineeslpydiphrarmisliesgwaqnpderpsflkclielepvlrtfeei
tfleaviqlkktklqsv

    Sequence, based on observed residues (ATOM records):
    >6fu5A (A:)
aicsalptipyhkladlrylsrgasgtvssarhadwrvqvavkhltplldserkdvlrea
eilhkarfsyilpilgicnepeflgivteympngslnellhrkteypdvawplrfrilhe
ialgvnylhnmtppllhhdlktqnilldnefhvkiadfglgtiiymppenyepsikhdiy
syavitwevlsrkqpfedvtnplqimysvsqghrpvineeslpydiphrarmisliesgw
aqnpderpsflkclielepvlrtfeeitfleaviqlkktklq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6fu5B (B:)
smgeaicsalptipyhkladlrylsrgasgtvssarhadwrvqvavkhlhihtplldser
kdvlreaeilhkarfsyilpilgicnepeflgivteympngslnellhrkteypdvawpl
rfrilheialgvnylhnmtppllhhdlktqnilldnefhvkiadfglskwrmmslsqsrs
sksapeggtiiymppenyepgqksrasikhdiysyavitwevlsrkqpfedvtnplqimy
svsqghrpvineeslpydiphrarmisliesgwaqnpderpsflkclielepvlrtfeei
tfleaviqlkktklqsv

    Sequence, based on observed residues (ATOM records):
    >6fu5B (B:)
aicsalptipyhkladlrylsrgasgtvssarhadwrvqvavkhlhlldserkdvlreae
ilhkarfsyilpilgicnepeflgivteympngslnellhrkteypdvawplrfrilhei
algvnylhnmtppllhhdlktqnilldnefhvkiadfgtiiymppenyepgqksrasikh
diysyavitwevlsrkqpfedvtnplqimysvsqghrpvineeslpydiphrarmislie
sgwaqnpderpsflkclielepvlrtfeeitfleaviqlkktklqs