PDB entry 6ft7

View 6ft7 on RCSB PDB site
Description: Crystal structure of CLK3 in complex with compound 8a
Class: transferase
Keywords: kinase, inhibitor, splicing kinase, CLK, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2018-02-20, released 2018-05-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-05-16, with a file datestamp of 2018-05-11.
Experiment type: XRAY
Resolution: 2.02 Å
R-factor: N/A
AEROSPACI score: 0.3 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity protein kinase CLK3
    Species: Homo sapiens [TaxId:9606]
    Gene: CLK3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ft7a_
  • Chain 'B':
    Compound: Dual specificity protein kinase CLK3
    Species: Homo sapiens [TaxId:9606]
    Gene: CLK3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ft7b_
  • Heterogens: IOD, EDO, E6Q, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ft7A (A:)
smqsskrssrsveddkeghlvcrigdwlqeryeivgnlgegtfgkvvecldhargksqva
lkiirnvgkyreaarleinvlkkikekdkenkflcvlmsdwfnfhghmciafellgkntf
eflkennfqpyplphvrhmayqlchalrflhenqlthtdlkpenilfvnsefetlynehk
sceeksvkntsirvadfgsatfdhehhttivatrhyrppevilelgwaqpcdvwsigcil
feyyrgftlfqthenrehlvmmekilgpipshmihrtrkqkyfykgglvwdenssdgryv
kenckplksymlqdslehvqlfdlmrrmlefdpaqritlaeallhpffagltpeersfht

    Sequence, based on observed residues (ATOM records): (download) 
    >6ft7A (A:)
skrssrsveddkeghlvcrigdwlqeryeivgnlgegtfgkvvecldhargksqvalkii
rnvgkyreaarleinvlkkikekdkenkflcvlmsdwfnfhghmciafellgkntfeflk
ennfqpyplphvrhmayqlchalrflhenqlthtdlkpenilfvnsefetlynehkscee
ksvkntsirvadfgsatfdhehhttivatrhyrppevilelgwaqpcdvwsigcilfeyy
rgftlfqthenrehlvmmekilgpipshmihrtrkqkyfykgglvwdenssdgryvkenc
kplksymlqdslehvqlfdlmrrmlefdpaqritlaeallhpffagltpeersfht

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ft7B (B:)
smqsskrssrsveddkeghlvcrigdwlqeryeivgnlgegtfgkvvecldhargksqva
lkiirnvgkyreaarleinvlkkikekdkenkflcvlmsdwfnfhghmciafellgkntf
eflkennfqpyplphvrhmayqlchalrflhenqlthtdlkpenilfvnsefetlynehk
sceeksvkntsirvadfgsatfdhehhttivatrhyrppevilelgwaqpcdvwsigcil
feyyrgftlfqthenrehlvmmekilgpipshmihrtrkqkyfykgglvwdenssdgryv
kenckplksymlqdslehvqlfdlmrrmlefdpaqritlaeallhpffagltpeersfht

    Sequence, based on observed residues (ATOM records): (download) 
    >6ft7B (B:)
skrssrsveddkeghlvcrigdwlqeryeivgnlgegtfgkvvecldhargksqvalkii
rnvgkyreaarleinvlkkikekdkenkflcvlmsdwfnfhghmciafellgkntfeflk
ennfqpyplphvrhmayqlchalrflhenqlthtdlkpenilfvnsefetlynehkscee
ksvkntsirvadfgsatfdhehhttivatrhyrppevilelgwaqpcdvwsigcilfeyy
rgftlfqthenrehlvmmekilgpipshmihrtrkqkyfykgglvwdenssdgryvkenc
kplksymlqdslehvqlfdlmrrmlefdpaqritlaeallhpffagltpeersfht