PDB entry 6fsy

View 6fsy on RCSB PDB site
Description: Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand
Class: transcription
Keywords: Bromodomain, ligand, transcription, isoxazole, Structural Genomics, Structural Genomics Consortium, SGC
Deposited on 2018-02-20, released 2018-04-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 1.34 Å
R-factor: N/A
AEROSPACI score: 0.57 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bromodomain-containing protein 4
    Species: Homo sapiens [TaxId:9606]
    Gene: BRD4, HUNK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot O60885 (0-126)
      • conflict (1)
    Domains in SCOPe 2.08: d6fsya_
  • Heterogens: EDO, E5Q, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >6fsyA (A:)