PDB entry 6fs6

View 6fs6 on RCSB PDB site
Description: Influenza A/California/04/2009 (pH1N1) endonuclease with bound inhibitor, baloxavir acid (BXA)
Class: viral protein
Keywords: Influenza, endonuclease, inhibitor, VIRAL PROTEIN
Deposited on 2018-02-19, released 2018-07-11
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-07-11, with a file datestamp of 2018-07-06.
Experiment type: XRAY
Resolution: 2.29 Å
R-factor: N/A
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polymerase acidic protein,Polymerase acidic protein
    Species: Influenza A virus (A/California/04/2009(H1N1)) [TaxId:641501]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
    • Uniprot C3W5S0 (7-End)
      • expression tag (5-6)
    • Uniprot C3W5S0 (Start-192)
    Domains in SCOPe 2.08: d6fs6a1, d6fs6a2
  • Chain 'B':
    Compound: Polymerase acidic protein,Polymerase acidic protein
    Species: Influenza A virus (A/California/04/2009(H1N1)) [TaxId:641501]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
    • Uniprot C3W5S0 (7-End)
      • expression tag (5-6)
    • Uniprot C3W5S0 (Start-192)
    Domains in SCOPe 2.08: d6fs6b1, d6fs6b2
  • Chain 'C':
    Compound: Polymerase acidic protein,Polymerase acidic protein
    Species: Influenza A virus (A/California/04/2009(H1N1)) [TaxId:641501]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
    • Uniprot C3W5S0 (7-End)
      • expression tag (5-6)
    • Uniprot C3W5S0 (Start-192)
    Domains in SCOPe 2.08: d6fs6c1, d6fs6c2
  • Chain 'D':
    Compound: Polymerase acidic protein,Polymerase acidic protein
    Species: Influenza A virus (A/California/04/2009(H1N1)) [TaxId:641501]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
    • Uniprot C3W5S0 (7-End)
      • expression tag (5-6)
    • Uniprot C3W5S0 (Start-192)
    Domains in SCOPe 2.08: d6fs6d1, d6fs6d2
  • Chain 'E':
    Compound: Polymerase acidic protein,Polymerase acidic protein
    Species: Influenza A virus (A/California/04/2009(H1N1)) [TaxId:641501]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
    • Uniprot C3W5S0 (7-End)
      • expression tag (5-6)
    • Uniprot C3W5S0 (Start-192)
    Domains in SCOPe 2.08: d6fs6e1, d6fs6e2
  • Chain 'F':
    Compound: Polymerase acidic protein,Polymerase acidic protein
    Species: Influenza A virus (A/California/04/2009(H1N1)) [TaxId:641501]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
    • Uniprot C3W5S0 (7-End)
      • expression tag (6)
    • Uniprot C3W5S0 (Start-192)
    Domains in SCOPe 2.08: d6fs6f1, d6fs6f2
  • Heterogens: MN, E4Z, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fs6A (A:)
gmgsgmamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfgs
gdpnallkhrfeiiegrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrr
evhiyylekankiksekthihifsftgeematkadytldeesrariktrlftirqemasr
slwdsfrqserge

    Sequence, based on observed residues (ATOM records): (download) 
    >6fs6A (A:)
mamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfkhrfeii
egrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrrevhiyylekankik
kthihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqserge

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6fs6B (B:)
gmgsgmamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfgs
gdpnallkhrfeiiegrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrr
evhiyylekankiksekthihifsftgeematkadytldeesrariktrlftirqemasr
slwdsfrqserge

    Sequence, based on observed residues (ATOM records): (download) 
    >6fs6B (B:)
mamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfkhrfeii
egrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrrevhiyylekankik
thihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqserge

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6fs6C (C:)
gmgsgmamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfgs
gdpnallkhrfeiiegrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrr
evhiyylekankiksekthihifsftgeematkadytldeesrariktrlftirqemasr
slwdsfrqserge

    Sequence, based on observed residues (ATOM records): (download) 
    >6fs6C (C:)
mamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdkhrfeiie
grdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrrevhiyylekankikk
thihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqserge

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6fs6D (D:)
gmgsgmamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfgs
gdpnallkhrfeiiegrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrr
evhiyylekankiksekthihifsftgeematkadytldeesrariktrlftirqemasr
slwdsfrqserge

    Sequence, based on observed residues (ATOM records): (download) 
    >6fs6D (D:)
mamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfhrfeiie
grdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrrevhiyylekankikk
thihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqserge

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6fs6E (E:)
gmgsgmamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfgs
gdpnallkhrfeiiegrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrr
evhiyylekankiksekthihifsftgeematkadytldeesrariktrlftirqemasr
slwdsfrqserge

    Sequence, based on observed residues (ATOM records): (download) 
    >6fs6E (E:)
mamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdlkhrfeii
egrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrrevhiyylekankik
kthihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqserge

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >6fs6F (F:)
gmgsgmamedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdfgs
gdpnallkhrfeiiegrdrimawtvvnsicnttgvekpkflpdlydykenrfieigvtrr
evhiyylekankiksekthihifsftgeematkadytldeesrariktrlftirqemasr
slwdsfrqserge

    Sequence, based on observed residues (ATOM records): (download) 
    >6fs6F (F:)
amedfvrqcfnpmivelaekamkeygedpkietnkfaaicthlevcfmysdhrfeiiegr
drimawtvvnsicnttgvekpkflpdlydykenrfieigvtrrevhiyylekankikkth
ihifsftgeematkadytldeesrariktrlftirqemasrslwdsfrqserge