PDB entry 6fs2

View 6fs2 on RCSB PDB site
Description: MCL1 in complex with indole acid ligand
Class: immune system
Keywords: MCL1, indole acid, IMMUNE SYSTEM
Deposited on 2018-02-18, released 2018-12-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-02, with a file datestamp of 2019-09-27.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.19 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1, BCL2L3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07820 (2-153)
      • expression tag (0-1)
      • conflict (21)
      • conflict (27)
      • conflict (29-30)
      • conflict (33-34)
      • conflict (36)
    Domains in SCOPe 2.08: d6fs2a1, d6fs2a2
  • Chain 'B':
    Compound: Induced myeloid leukemia cell differentiation protein Mcl-1
    Species: Homo sapiens [TaxId:9606]
    Gene: MCL1, BCL2L3
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q07820 (2-End)
      • expression tag (0-1)
      • conflict (21)
      • conflict (27)
      • conflict (29-30)
      • conflict (33-34)
      • conflict (36)
    Domains in SCOPe 2.08: d6fs2b1, d6fs2b2
  • Heterogens: E4K, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fs2A (A:)
ddlyrqsleiisrylreqatgskdtkplgeagaagrraletlrrvgdgvqrnhetafqgm
lrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepla
esitdvlvrtkrdwlvkqrgwdgfveffhvedle

    Sequence, based on observed residues (ATOM records): (download) 
    >6fs2A (A:)
ddlyrqsleiisrylreqatgskdplgeagaagrraletlrrvgdgvqrnhetafqgmlr
kldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplaes
itdvlvrtkrdwlvkqrgwdgfveffhvedle

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6fs2B (B:)
ddlyrqsleiisrylreqatgskdtkplgeagaagrraletlrrvgdgvqrnhetafqgm
lrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepla
esitdvlvrtkrdwlvkqrgwdgfveffhvedle

    Sequence, based on observed residues (ATOM records): (download) 
    >6fs2B (B:)
ddlyrqsleiisrylreqatgskdplgeagaagrraletlrrvgdgvqrnhetafqgmlr
kldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqescieplaes
itdvlvrtkrdwlvkqrgwdgfveffhvedl