PDB entry 6fr2

View 6fr2 on RCSB PDB site
Description: Soluble epoxide hydrolase in complex with LK864
Class: hydrolase
Keywords: Inhibitor, Complex, sEH, Hydrolase
Deposited on 2018-02-15, released 2018-09-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-02-24, with a file datestamp of 2021-02-19.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional epoxide hydrolase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHX2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fr2a_
  • Heterogens: E3N, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fr2A (A:)
maslntpaplptscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqi
palaqagyrvlamdmkgygessappeieeycmevlckemvtfldklglsqavfighdwgg
mlvwymalfypervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaele
qnlsrtfkslfrasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksg
frgplnwyrnmernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrgh
iedcghwtqmdkptevnqilikwldsdarnppvvskmllehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6fr2A (A:)
ptscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrv
lamdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfy
pervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfksl
frasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrn
mernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqm
dkptevnqilikwldsdar