PDB entry 6fr2

View 6fr2 on RCSB PDB site
Description: Soluble epoxide hydrolase in complex with LK864
Class: hydrolase
Keywords: Inhibitor, Complex, sEH, Hydrolase
Deposited on 2018-02-15, released 2018-09-12
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-09-12, with a file datestamp of 2018-09-07.
Experiment type: XRAY
Resolution: 2.26 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Bifunctional epoxide hydrolase 2
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHX2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d6fr2a_
  • Heterogens: E3N, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6fr2A (A:)
    maslntpaplptscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqi
    palaqagyrvlamdmkgygessappeieeycmevlckemvtfldklglsqavfighdwgg
    mlvwymalfypervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaele
    qnlsrtfkslfrasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksg
    frgplnwyrnmernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrgh
    iedcghwtqmdkptevnqilikwldsdarnppvvskmllehhhhhh
    

    Sequence, based on observed residues (ATOM records): (download)
    >6fr2A (A:)
    ptscnpsdmshgyvtvkprvrlhfvelgsgpavclchgfpeswyswryqipalaqagyrv
    lamdmkgygessappeieeycmevlckemvtfldklglsqavfighdwggmlvwymalfy
    pervravaslntpfipanpnmsplesikanpvfdyqlyfqepgvaeaeleqnlsrtfksl
    frasdesvlsmhkvceagglfvnspeepslsrmvteeeiqfyvqqfkksgfrgplnwyrn
    mernwkwackslgrkilipalmvtaekdfvlvpqmsqhmedwiphlkrghiedcghwtqm
    dkptevnqilikwldsdar