PDB entry 6fqk

View 6fqk on RCSB PDB site
Description: GluA2(flop) S729C ligand binding core dimer bound to ZK200775 at 1.98 Angstrom resolution
Class: membrane protein
Keywords: AMPAR receptor, Ligand binding domain, competitive antagonist, Cross-linked dimer, MEMBRANE PROTEIN
Deposited on 2018-02-14, released 2019-03-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-10-02, with a file datestamp of 2019-09-27.
Experiment type: XRAY
Resolution: 1.98 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor 2,Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Gria2, Glur2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (Start-128)
      • linker (129-130)
    • Uniprot P19491 (131-End)
      • conflict (228)
    Domains in SCOPe 2.08: d6fqka_
  • Chain 'B':
    Compound: Glutamate receptor 2,Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Gria2, Glur2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (Start-128)
      • linker (129-130)
    • Uniprot P19491 (131-End)
      • conflict (228)
    Domains in SCOPe 2.08: d6fqkb_
  • Heterogens: ZK1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fqkA (A:)
gsamgsgndtsrganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcg
fkykltivgdgkygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfms
lgisimikkgtpiesaedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaeps
vfvrttaegvarvrkskgkyayllestmneyieqrkpcdtmkvggnldckgygiatpkgs
slgnavnlavlklneqglldklknkwwydkgecgsg

    Sequence, based on observed residues (ATOM records): (download) 
    >6fqkA (A:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
aedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvggnldckgygiatpkgsslgnavnlavlklne
qglldklknkwwydkgecg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6fqkB (B:)
gsamgsgndtsrganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcg
fkykltivgdgkygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfms
lgisimikkgtpiesaedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaeps
vfvrttaegvarvrkskgkyayllestmneyieqrkpcdtmkvggnldckgygiatpkgs
slgnavnlavlklneqglldklknkwwydkgecgsg

    Sequence, based on observed residues (ATOM records): (download) 
    >6fqkB (B:)
ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
aedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
skgkyayllestmneyieqrkpcdtmkvggnldckgygiatpkgsslgnavnlavlklne
qglldklknkwwydkgec