PDB entry 6fqg

View 6fqg on RCSB PDB site
Description: GluA2(flop) G724C ligand binding core dimer bound to L-Glutamate (Form A) at 2.34 Angstrom resolution
Class: membrane protein
Keywords: AMPAR receptor, Ligand binding domain, Competitive antagonist, Cross-linked dimer, MEMBRANE PROTEIN
Deposited on 2018-02-14, released 2019-03-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-13, with a file datestamp of 2019-03-08.
Experiment type: XRAY
Resolution: 2.34 Å
R-factor: N/A
AEROSPACI score: 0.24 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glutamate receptor 2,Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Gria2, Glur2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (Start-116)
      • linker (117-118)
    • Uniprot P19491 (119-End)
      • conflict (211)
    Domains in SCOPe 2.08: d6fqga_
  • Chain 'B':
    Compound: Glutamate receptor 2,Glutamate receptor 2
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Gria2, Glur2
    Database cross-references and differences (RAF-indexed):
    • Uniprot P19491 (Start-116)
      • linker (117-118)
    • Uniprot P19491 (119-End)
      • conflict (211)
    Domains in SCOPe 2.08: d6fqgb_
  • Heterogens: GGL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6fqgA (A:)
    ganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgk
    ygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtp
    iesaedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvar
    vrkskgkyayllestmneyieqrkpcdtmkvcgnldskgygiatpkgsslgnavnlavlk
    lneqglldklknkwwydkgecgsg
    

    Sequence, based on observed residues (ATOM records): (download)
    >6fqgA (A:)
    ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
    rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
    aedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
    skgkyayllestmneyieqrkpcdtmkvcgnldskgygiatpkgsslgnavnlavlklne
    qglldklknkwwydkgec
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6fqgB (B:)
    ganktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgk
    ygardadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtp
    iesaedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvar
    vrkskgkyayllestmneyieqrkpcdtmkvcgnldskgygiatpkgsslgnavnlavlk
    lneqglldklknkwwydkgecgsg
    

    Sequence, based on observed residues (ATOM records): (download)
    >6fqgB (B:)
    ktvvvttilespyvmmkknhemlegneryegycvdlaaeiakhcgfkykltivgdgkyga
    rdadtkiwngmvgelvygkadiaiapltitlvreevidfskpfmslgisimikkgtpies
    aedlskqteiaygtldsgstkeffrrskiavfdkmwtymrsaepsvfvrttaegvarvrk
    skgkyayllestmneyieqrkpcdtmkvcgnldskgygiatpkgsslgnavnlavlklne
    qglldklknkwwydkgecg