PDB entry 6fof

View 6fof on RCSB PDB site
Description: Crystal structure of a crystallized variant of h-Gal3: Gal-3[NTS/VII-IX]
Class: sugar binding protein
Keywords: Galectin, apoptosis, glycosylation, sugar binding protein
Deposited on 2018-02-07, released 2018-07-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Galectin-3,Galectin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS3, MAC2
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Galectin-3,Galectin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS3, MAC2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fofb_
  • Chain 'C':
    Compound: Galectin-3,Galectin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS3, MAC2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fofc_
  • Chain 'D':
    Compound: Galectin-3,Galectin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS3, MAC2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fofd_
  • Chain 'E':
    Compound: Galectin-3,Galectin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS3, MAC2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fofe_
  • Chain 'F':
    Compound: Galectin-3,Galectin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS3, MAC2
    Database cross-references and differences (RAF-indexed):
  • Chain 'G':
    Compound: Galectin-3,Galectin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS3, MAC2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fofg_
  • Chain 'H':
    Compound: Galectin-3,Galectin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS3, MAC2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fofh_
  • Chain 'I':
    Compound: Galectin-3,Galectin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS3, MAC2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fofi_
  • Chain 'J':
    Compound: Galectin-3,Galectin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS3, MAC2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fofj_
  • Chain 'K':
    Compound: Galectin-3,Galectin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS3, MAC2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fofk_
  • Chain 'L':
    Compound: Galectin-3,Galectin-3
    Species: Homo sapiens [TaxId:9606]
    Gene: LGALS3, MAC2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fofl_
  • Heterogens: SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6fofB (B:)
adnfslhdalsgsgnpnpqgwpgvypgppsgpgaypssgqpsatgaypatgpygapagpl
ivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrvivcn
tkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneiskl
gisgdidltsasytmi

    Sequence, based on observed residues (ATOM records): (download) 
    >6fofB (B:)
plivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrviv
cntkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneis
klgisgdidltsasytmi

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6fofC (C:)
adnfslhdalsgsgnpnpqgwpgvypgppsgpgaypssgqpsatgaypatgpygapagpl
ivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrvivcn
tkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneiskl
gisgdidltsasytmi

    Sequence, based on observed residues (ATOM records): (download) 
    >6fofC (C:)
plivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrviv
cntkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneis
klgisgdidltsasytmi

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >6fofD (D:)
adnfslhdalsgsgnpnpqgwpgvypgppsgpgaypssgqpsatgaypatgpygapagpl
ivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrvivcn
tkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneiskl
gisgdidltsasytmi

    Sequence, based on observed residues (ATOM records): (download) 
    >6fofD (D:)
ypatgpygapagplivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfn
prfnennrrvivcntkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllq
ynhrvkklneisklgisgdidltsasytmi

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >6fofE (E:)
adnfslhdalsgsgnpnpqgwpgvypgppsgpgaypssgqpsatgaypatgpygapagpl
ivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrvivcn
tkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneiskl
gisgdidltsasytmi

    Sequence, based on observed residues (ATOM records): (download) 
    >6fofE (E:)
plivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrviv
cntkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneis
klgisgdidltsasytmi

  • Chain 'F':
    No sequence available.

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >6fofG (G:)
adnfslhdalsgsgnpnpqgwpgvypgppsgpgaypssgqpsatgaypatgpygapagpl
ivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrvivcn
tkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneiskl
gisgdidltsasytmi

    Sequence, based on observed residues (ATOM records): (download) 
    >6fofG (G:)
plivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrviv
cntkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneis
klgisgdidltsasytmi

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >6fofH (H:)
adnfslhdalsgsgnpnpqgwpgvypgppsgpgaypssgqpsatgaypatgpygapagpl
ivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrvivcn
tkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneiskl
gisgdidltsasytmi

    Sequence, based on observed residues (ATOM records): (download) 
    >6fofH (H:)
plivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrviv
cntkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneis
klgisgdidltsasytmi

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >6fofI (I:)
adnfslhdalsgsgnpnpqgwpgvypgppsgpgaypssgqpsatgaypatgpygapagpl
ivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrvivcn
tkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneiskl
gisgdidltsasytmi

    Sequence, based on observed residues (ATOM records): (download) 
    >6fofI (I:)
plivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrviv
cntkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneis
klgisgdidltsasytmi

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >6fofJ (J:)
adnfslhdalsgsgnpnpqgwpgvypgppsgpgaypssgqpsatgaypatgpygapagpl
ivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrvivcn
tkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneiskl
gisgdidltsasytmi

    Sequence, based on observed residues (ATOM records): (download) 
    >6fofJ (J:)
plivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrviv
cntkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneis
klgisgdidltsasytmi

  • Chain 'K':
    Sequence, based on SEQRES records: (download) 
    >6fofK (K:)
adnfslhdalsgsgnpnpqgwpgvypgppsgpgaypssgqpsatgaypatgpygapagpl
ivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrvivcn
tkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneiskl
gisgdidltsasytmi

    Sequence, based on observed residues (ATOM records): (download) 
    >6fofK (K:)
plivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrviv
cntkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneis
klgisgdidltsasytmi

  • Chain 'L':
    Sequence, based on SEQRES records: (download) 
    >6fofL (L:)
adnfslhdalsgsgnpnpqgwpgvypgppsgpgaypssgqpsatgaypatgpygapagpl
ivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrvivcn
tkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneiskl
gisgdidltsasytmi

    Sequence, based on observed residues (ATOM records): (download) 
    >6fofL (L:)
plivpynlplpggvvprmlitilgtvkpnanrialdfqrgndvafhfnprfnennrrviv
cntkldnnwgreerqsvfpfesgkpfkiqvlvepdhfkvavndahllqynhrvkklneis
klgisgdidltsasytmi