PDB entry 6fo6

View 6fo6 on RCSB PDB site
Description: cryoem structure of bovine cytochrome bc1 in complex with the anti- malarial inhibitor scr0911
Deposited on 2018-02-06, released 2018-02-28
The last revision was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: EM
Resolution: 4.1 Å
R-factor: N/A
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cytochrome b-c1 complex subunit 1, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: Cytochrome b-c1 complex subunit 2, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: cytochrome b
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: Cytochrome c1, heme protein, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'E':
    Compound: Cytochrome b-c1 complex subunit Rieske, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'F':
    Compound: Cytochrome b-c1 complex subunit 7
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00129
      • conflict (56)
  • Chain 'G':
    Compound: Cytochrome b-c1 complex subunit 8
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'H':
    Compound: cytochrome b-c1 complex subunit 6, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'J':
    Compound: Cytochrome b-c1 complex subunit 9
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'N':
    Compound: Cytochrome b-c1 complex subunit 1, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'O':
    Compound: Cytochrome b-c1 complex subunit 2, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'P':
    Compound: cytochrome b
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'Q':
    Compound: Cytochrome c1, heme protein, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'R':
    Compound: Cytochrome b-c1 complex subunit Rieske, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'S':
    Compound: Cytochrome b-c1 complex subunit 7
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00129
      • conflict (56)
  • Chain 'T':
    Compound: Cytochrome b-c1 complex subunit 8
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'U':
    Compound: cytochrome b-c1 complex subunit 6, mitochondrial
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Chain 'W':
    Compound: Cytochrome b-c1 complex subunit 9
    Species: Bos taurus [TaxId:9913]
    Database cross-references and differences (RAF-indexed):
  • Heterogens: HEM, DY2, HEC

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6fo6A (A:)
maasavcraagagtrvllrtrrspallrssdlrgtatyaqalqsvpetqvsqldnglrva
seqssqptctvgvwidagsryeseknngagyfvehlafkgtknrpgnalekevesmgahl
naystrehtayyikalskdlpkavelladivqncsledsqiekerdvilqelqendtsmr
dvvfnylhatafqgtplaqsvegpsenvrklsradlteylsrhykaprmvlaaagglehr
qlldlaqkhfsglsgtydedavptlspcrftgsqichredglplahvaiavegpgwahpd
nvalqvanaiighydctygggahlssplasiaatnklcqsfqtfnicyadtgllgahfvc
dhmsiddmmfvlqgqwmrlctsatesevlrgknllrnalvshldgttpvcedigrsllty
grriplaewesriaevdarvvrevcskyfydqcpavagfgpieqlpdynrirsgmfwlrf

    Sequence, based on observed residues (ATOM records):
    >6fo6A (A:)
atyaqalqsvpetqvsqldnglrvaseqssqptctvgvwidagsryeseknngagyfveh
lafkgtknrpgnalekevesmgahlnaystrehtayyikalskdlpkavelladivqncs
ledsqiekerdvilqelqendtsmrdvvfnylhatafqgtplaqsvegpsenvrklsrad
lteylsrhykaprmvlaaagglehrqlldlaqkhfsglsgtydedavptlspcrftgsqi
chredglplahvaiavegpgwahpdnvalqvanaiighydctygggahlssplasiaatn
klcqsfqtfnicyadtgllgahfvcdhmsiddmmfvlqgqwmrlctsatesevlrgknll
rnalvshldgttpvcedigrslltygrriplaewesriaevdarvvrevcskyfydqcpa
vagfgpieqlpdynrirsgmfwlr

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6fo6B (B:)
mklltragslsrfyslkvapkvkateapagvpphpqdleftrlpnglviaslenyapasr
iglfikagsryensnnlgtshllrlasslttkgassfkitrgieavggklsvtstrenma
ytveclrddvdilmefllnvttapefrrwevaalqpqlridkavalqnpqahvienlhaa
ayrnalanslycpdyrigkvtpvelhdyvqnhftsarmaliglgvshpvlkqvaeqflni
rgglglsgakakyhggeireqngdslvhaalvaesaaigsaeanafsvlqhvlgagphvk
rgsnatsslyqavakgvhqpfdvsafnasysdsglfgfytisqaasagdvikaaynqvkt
iaqgnlsnpdvqaaknklkagylmsvessegfldevgsqalaagsytppstvlqqidava
dadvinaakkfvsgrksmaasgnlghtpfidel

    Sequence, based on observed residues (ATOM records):
    >6fo6B (B:)
qdleftrlpnglviaslenyapasriglfikagsryensnnlgtshllrlasslttkgas
sfkitrgieavggklsvtstrenmaytveclrddvdilmefllnvttapefrrwevaalq
pqlridkavalqnpqahvienlhaaayrnalanslycpdyrigkvtpvelhdyvqnhfts
armaliglgvshpvlkqvaeqflnirlsgakakyhggeireqngdslvhaalvaesaaig
saeanafsvlqhvlgagphvkrgsnatsslyqavakgvhqpfdvsafnasysdsglfgfy
tisqaasagdvikaaynqvktiaqgnlsnpdvqaaknklkagylmsvessegfldevgsq
alaagsytppstvlqqidavadadvinaakkfvsgrksmaasgnlghtpfidel

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6fo6C (C:)
mtnirkshplmkivnnafidlpapsnisswwnfgsllgiclilqiltglflamhytsdtt
tafssvthicrdvnygwiirymhangasmfficlymhvgrglyygsytfletwnigvill
ltvmatafmgyvlpwgqmsfwgatvitnllsaipyigtnlvewiwggfsvdkatltrffa
fhfilpfiimaiamvhllflhetgsnnptgissdvdkipfhpyytikdilgalllilalm
llvlfapdllgdpdnytpanplntpphikpewyflfayailrsipnklggvlalafsili
lalipllhtskqrsmmfrplsqclfwalvadlltltwiggqpvehpyitigqlasvlyfl
lilvlmptagtienkllkw

    Sequence, based on observed residues (ATOM records):
    >6fo6C (C:)
lmkivnnafidlpapsnisswwnfgsllgiclilqiltglflamhytsdtttafssvthi
crdvnygwiirymhangasmfficlymhvgrglyygsytfletwnigvillltvmatafm
gyvlpwgqmsfwgatvitnllsaipyigtnlvewiwggfsvdkatltrffafhfilpfii
maiamvhllflhetgsnnptgissdvdkipfhpyytikdilgalllilalmllvlfapdl
lgdpdnytpanplntpphikpewyflfayailrsipnklggvlalafsililalipllht
skqrsmmfrplsqclfwalvadlltltwiggqpvehpyitigqlasvlyfllilvlmpta
gtienkllkw

  • Chain 'D':
    Sequence, based on SEQRES records:
    >6fo6D (D:)
maaaaatlrgamvgprgaglpgarargllcgarpgqlplrtpqavslssksglsrgrkvi
lsalgmlaaggaglavalhsavsasdlelhppsypwshrgllssldhtsirrgfqvykqv
csschsmdyvayrhlvgvcytedeakalaeevevqdgpnedgemfmrpgklsdyfpkpyp
npeaaraanngalppdlsyivrarhggedyvfslltgycepptgvslreglyfnpyfpgq
aigmappiynevlefddgtpatmsqvakdvctflrwaaepehdhrkrmglkmllmmglll
plvyamkrhkwsvlksrklayrppk

    Sequence, based on observed residues (ATOM records):
    >6fo6D (D:)
elhppsypwshrgllssldhtsirrgfqvykqvcsschsmdyvayrhlvgvcytedeaka
laeevevqdgpnedgemfmrpgklsdyfpkpypnpeaaraanngalppdlsyivrarhgg
edyvfslltgycepptgvslreglyfnpyfpgqaigmappiynevlefddgtpatmsqva
kdvctflrwaaepehdhrkrmglkmllmmglllplvyamkrhkwsvlksrklayrpp

  • Chain 'E':
    Sequence, based on SEQRES records:
    >6fo6E (E:)
mlsvaarsgpfapvlsatsrgvagalrplvqaavpatsespvldlkrsvlcreslrgqaa
grplvasvslnvpasvryshtdikvpdfsdyrrpevldstksskessearkgfsylvtat
ttvgvayaaknvvsqfvssmsasadvlamskieiklsdipegknmafkwrgkplfvrhrt
kkeidqeaavevsqlrdpqhdlervkkpewviligvcthlgcvpianagdfggyycpchg
shydasgrirkgpaplnlevpsyeftsddmvivg

    Sequence, based on observed residues (ATOM records):
    >6fo6E (E:)
shtdikvpdfsdyrrpevldstksskessearkgfsylvtatttvgvayaaknvvsqfvs
smsasadvlamskieiklegknmafkwrgkplfveidqeaavevsqlrdpqhdlervkkp
ewviligvcthlgcvpianggyycpcydasgrirkgpaplnlevpsyeftsddmvivg

  • Chain 'F':
    Sequence, based on SEQRES records:
    >6fo6F (F:)
magrpavsassrwlegirkwyynaagfnklglmrddtihenddvkeairrlpenlyddrv
frikraldlsmrqqilpkeqwtkyeedksylepylkevirerkereewakk

    Sequence, based on observed residues (ATOM records):
    >6fo6F (F:)
wlegirkwyynaagfnklglmrddtihenddvkeairrlpenlyddrvfrikraldlsmr
qqilpkeqwtkyeedksylepylkevirerkereewak

  • Chain 'G':
    Sequence, based on SEQRES records:
    >6fo6G (G:)
mgrqfghltrvrhvityslspfeqrafphyfskgipnvlrrtracilrvappfvafylvy
twgtqefekskrknpaayendr

    Sequence, based on observed residues (ATOM records):
    >6fo6G (G:)
rqfghltrvrhvityslspfeqrafphyfskgipnvlrrtracilrvappfvafylvytw
gtqefekskrkn

  • Chain 'H':
    Sequence, based on SEQRES records:
    >6fo6H (H:)
mgledeqrmltgsgdpkeeeeeeeelvdplttvreqceqlekcvkarerlelcdervssr
sqteedcteelldflhardhcvahklfnslk

    Sequence, based on observed residues (ATOM records):
    >6fo6H (H:)
lvdplttvreqceqlekcvkarerlelcdervssrsqteedcteelldflhardhcvahk
lfnsl

  • Chain 'J':
    Sequence, based on SEQRES records:
    >6fo6J (J:)
mvaptltarlysllfrrtstfaltivvgalfferafdqgadaiyehinegklwkhikhky
enke

    Sequence, based on observed residues (ATOM records):
    >6fo6J (J:)
ptltarlysllfrrtstfaltivvgalfferafdqgadaiyehinegklwkhikhkye

  • Chain 'N':
    Sequence, based on SEQRES records:
    >6fo6N (N:)
maasavcraagagtrvllrtrrspallrssdlrgtatyaqalqsvpetqvsqldnglrva
seqssqptctvgvwidagsryeseknngagyfvehlafkgtknrpgnalekevesmgahl
naystrehtayyikalskdlpkavelladivqncsledsqiekerdvilqelqendtsmr
dvvfnylhatafqgtplaqsvegpsenvrklsradlteylsrhykaprmvlaaagglehr
qlldlaqkhfsglsgtydedavptlspcrftgsqichredglplahvaiavegpgwahpd
nvalqvanaiighydctygggahlssplasiaatnklcqsfqtfnicyadtgllgahfvc
dhmsiddmmfvlqgqwmrlctsatesevlrgknllrnalvshldgttpvcedigrsllty
grriplaewesriaevdarvvrevcskyfydqcpavagfgpieqlpdynrirsgmfwlrf

    Sequence, based on observed residues (ATOM records):
    >6fo6N (N:)
atyaqalqsvpetqvsqldnglrvaseqssqptctvgvwidagsryeseknngagyfveh
lafkgtknrpgnalekevesmgahlnaystrehtayyikalskdlpkavelladivqncs
ledsqiekerdvilqelqendtsmrdvvfnylhatafqgtplaqsvegpsenvrklsrad
lteylsrhykaprmvlaaagglehrqlldlaqkhfsglsgtydedavptlspcrftgsqi
chredglplahvaiavegpgwahpdnvalqvanaiighydctygggahlssplasiaatn
klcqsfqtfnicyadtgllgahfvcdhmsiddmmfvlqgqwmrlctsatesevlrgknll
rnalvshldgttpvcedigrslltygrriplaewesriaevdarvvrevcskyfydqcpa
vagfgpieqlpdynrirsgmfwlr

  • Chain 'O':
    Sequence, based on SEQRES records:
    >6fo6O (O:)
mklltragslsrfyslkvapkvkateapagvpphpqdleftrlpnglviaslenyapasr
iglfikagsryensnnlgtshllrlasslttkgassfkitrgieavggklsvtstrenma
ytveclrddvdilmefllnvttapefrrwevaalqpqlridkavalqnpqahvienlhaa
ayrnalanslycpdyrigkvtpvelhdyvqnhftsarmaliglgvshpvlkqvaeqflni
rgglglsgakakyhggeireqngdslvhaalvaesaaigsaeanafsvlqhvlgagphvk
rgsnatsslyqavakgvhqpfdvsafnasysdsglfgfytisqaasagdvikaaynqvkt
iaqgnlsnpdvqaaknklkagylmsvessegfldevgsqalaagsytppstvlqqidava
dadvinaakkfvsgrksmaasgnlghtpfidel

    Sequence, based on observed residues (ATOM records):
    >6fo6O (O:)
qdleftrlpnglviaslenyapasriglfikagsryensnnlgtshllrlasslttkgas
sfkitrgieavggklsvtstrenmaytveclrddvdilmefllnvttapefrrwevaalq
pqlridkavalqnpqahvienlhaaayrnalanslycpdyrigkvtpvelhdyvqnhfts
armaliglgvshpvlkqvaeqflnirakakyhggeireqngdslvhaalvaesaaigsae
anafsvlqhvlgagphvkrgsnatsslyqavakgvhqpfdvsafnasysdsglfgfytis
qaasagdvikaaynqvktiaqgnlsnpdvqaaknklkagylmsvessegfldevgsqala
agsytppstvlqqidavadadvinaakkfvsgrksmaasgnlghtpfidel

  • Chain 'P':
    Sequence, based on SEQRES records:
    >6fo6P (P:)
mtnirkshplmkivnnafidlpapsnisswwnfgsllgiclilqiltglflamhytsdtt
tafssvthicrdvnygwiirymhangasmfficlymhvgrglyygsytfletwnigvill
ltvmatafmgyvlpwgqmsfwgatvitnllsaipyigtnlvewiwggfsvdkatltrffa
fhfilpfiimaiamvhllflhetgsnnptgissdvdkipfhpyytikdilgalllilalm
llvlfapdllgdpdnytpanplntpphikpewyflfayailrsipnklggvlalafsili
lalipllhtskqrsmmfrplsqclfwalvadlltltwiggqpvehpyitigqlasvlyfl
lilvlmptagtienkllkw

    Sequence, based on observed residues (ATOM records):
    >6fo6P (P:)
lmkivnnafidlpapsnisswwnfgsllgiclilqiltglflamhytsdtttafssvthi
crdvnygwiirymhangasmfficlymhvgrglyygsytfletwnigvillltvmatafm
gyvlpwgqmsfwgatvitnllsaipyigtnlvewiwggfsvdkatltrffafhfilpfii
maiamvhllflhetgsnnptgissdvdkipfhpyytikdilgalllilalmllvlfapdl
lgdpdnytpanplntpphikpewyflfayailrsipnklggvlalafsililalipllht
skqrsmmfrplsqclfwalvadlltltwiggqpvehpyitigqlasvlyfllilvlmpta
gtienkllkw

  • Chain 'Q':
    Sequence, based on SEQRES records:
    >6fo6Q (Q:)
maaaaatlrgamvgprgaglpgarargllcgarpgqlplrtpqavslssksglsrgrkvi
lsalgmlaaggaglavalhsavsasdlelhppsypwshrgllssldhtsirrgfqvykqv
csschsmdyvayrhlvgvcytedeakalaeevevqdgpnedgemfmrpgklsdyfpkpyp
npeaaraanngalppdlsyivrarhggedyvfslltgycepptgvslreglyfnpyfpgq
aigmappiynevlefddgtpatmsqvakdvctflrwaaepehdhrkrmglkmllmmglll
plvyamkrhkwsvlksrklayrppk

    Sequence, based on observed residues (ATOM records):
    >6fo6Q (Q:)
elhppsypwshrgllssldhtsirrgfqvykqvcsschsmdyvayrhlvgvcytedeaka
laeevevqdgpnedgemfmrpgklsdyfpkpypnpeaaraanngalppdlsyivrarhgg
edyvfslltgycepptgvslreglyfnpyfpgqaigmappiynevlefddgtpatmsqva
kdvctflrwaaepehdhrkrmglkmllmmglllplvyamkrhkwsvlksrklayrpp

  • Chain 'R':
    Sequence, based on SEQRES records:
    >6fo6R (R:)
mlsvaarsgpfapvlsatsrgvagalrplvqaavpatsespvldlkrsvlcreslrgqaa
grplvasvslnvpasvryshtdikvpdfsdyrrpevldstksskessearkgfsylvtat
ttvgvayaaknvvsqfvssmsasadvlamskieiklsdipegknmafkwrgkplfvrhrt
kkeidqeaavevsqlrdpqhdlervkkpewviligvcthlgcvpianagdfggyycpchg
shydasgrirkgpaplnlevpsyeftsddmvivg

    Sequence, based on observed residues (ATOM records):
    >6fo6R (R:)
shtdikvpdfsdyrrpevldstksskessearkgfsylvtatttvgvayaaknvvsqfvs
smsasadvlamskieiklegknmafkwrgkplfveidqeaavevsqlrdpqhdlervkkp
ewviligvcthlgcvpianggyycpcydasgrirkgpaplnlevpsyeftsddmvivg

  • Chain 'S':
    Sequence, based on SEQRES records:
    >6fo6S (S:)
magrpavsassrwlegirkwyynaagfnklglmrddtihenddvkeairrlpenlyddrv
frikraldlsmrqqilpkeqwtkyeedksylepylkevirerkereewakk

    Sequence, based on observed residues (ATOM records):
    >6fo6S (S:)
wlegirkwyynaagfnklglmrddtihenddvkeairrlpenlyddrvfrikraldlsmr
qqilpkeqwtkyeedksylepylkevirerkereewak

  • Chain 'T':
    Sequence, based on SEQRES records:
    >6fo6T (T:)
mgrqfghltrvrhvityslspfeqrafphyfskgipnvlrrtracilrvappfvafylvy
twgtqefekskrknpaayendr

    Sequence, based on observed residues (ATOM records):
    >6fo6T (T:)
rqfghltrvrhvityslspfeqrafphyfskgipnvlrrtracilrvappfvafylvytw
gtqefekskrkn

  • Chain 'U':
    Sequence, based on SEQRES records:
    >6fo6U (U:)
mgledeqrmltgsgdpkeeeeeeeelvdplttvreqceqlekcvkarerlelcdervssr
sqteedcteelldflhardhcvahklfnslk

    Sequence, based on observed residues (ATOM records):
    >6fo6U (U:)
lvdplttvreqceqlekcvkarerlelcdervssrsqteedcteelldflhardhcvahk
lfnsl

  • Chain 'W':
    Sequence, based on SEQRES records:
    >6fo6W (W:)
mvaptltarlysllfrrtstfaltivvgalfferafdqgadaiyehinegklwkhikhky
enke

    Sequence, based on observed residues (ATOM records):
    >6fo6W (W:)
ptltarlysllfrrtstfaltivvgalfferafdqgadaiyehinegklwkhikhky