PDB entry 6fnm

View 6fnm on RCSB PDB site
Description: Crystal Structure of Ephrin B4 (EphB4) Receptor Protein Kinase with Dasatinib
Class: transferase
Keywords: Inhibitor, Complex, Protein Tyrosine Kinase, Transferase
Deposited on 2018-02-04, released 2018-08-08
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-08-29, with a file datestamp of 2018-08-24.
Experiment type: XRAY
Resolution: 1.16 Å
R-factor: N/A
AEROSPACI score: 0.69 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Ephrin type-B receptor 4
    Species: Homo sapiens [TaxId:9606]
    Gene: EPHB4, HTK, MYK1, TYRO11
    Database cross-references and differences (RAF-indexed):
    • Uniprot P54760
      • engineered mutation (207)
      • engineered mutation (274)
    Domains in SCOPe 2.08: d6fnma_
  • Heterogens: 1N1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fnmA (A:)
gmdpneavrefakeidvsyvkieevigagefgevcrgrlkapgkkescvaiktlkggyte
rqrreflseasimgqfehpniirlegvvtnsmpvmiltefmengaldsflrlndgqftvi
qlvgmlrgiasgmrylaemsyvhrdlaarnilvnsnlvckvsdfglsrfleenssdptet
sslggkipirwtapeaiafrkftsasdvwsygivmwevmsfgerpywdmsnqdvinaieq
dyrlppppdcptslhqlmldcwqkdrnarprfpqivsaldkmirnpaslkivareng

    Sequence, based on observed residues (ATOM records): (download) 
    >6fnmA (A:)
keidvsyvkieevigagefgevcrgrlkapgkkescvaiktlkggyterqrreflseasi
mgqfehpniirlegvvtnsmpvmiltefmengaldsflrlndgqftviqlvgmlrgiasg
mrylaemsyvhrdlaarnilvnsnlvckvsdfglsrfleegkipirwtapeaiafrkfts
asdvwsygivmwevmsfgerpywdmsnqdvinaieqdyrlppppdcptslhqlmldcwqk
drnarprfpqivsaldkmirnpaslkivar