PDB entry 6fn1

View 6fn1 on RCSB PDB site
Description: zosuquidar and uic2 fab complex of human-mouse chimeric abcb1 (abcb1hm)
Deposited on 2018-02-02, released 2018-02-21
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: EM
Resolution: 3.58 Å
R-factor: N/A
AEROSPACI score: 0.17 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Human-mouse chimeric ABCB1 (ABCBHM)
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6FN1 (0-End)
  • Chain 'B':
    Compound: UIC2 Antigen Binding Fragment Light chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6FN1 (0-219)
  • Chain 'C':
    Compound: UIC2 Antigen binding fragment Heavy chain
    Species: Mus musculus [TaxId:10090]
    Database cross-references and differences (RAF-indexed):
    • PDB 6FN1 (0-224)
  • Heterogens: NAG, ZQU

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6fn1A (A:)
pavsvltmfryagwldrlymlvgtlaaiihgvalplmmlifgemtdifanagnledlmsn
itnrsdindtgffmnleedmttyayyytgigagvlivayiqvsfwllaagrqihkirqkf
fhaimnqeigwfdvhdvgelntrltddvskinegigdkigmffqamatffggfiigftrg
wkltlvilaispvlglsagiwakilssftdkelhayakagavaeevlaairtviafggqk
kelerynnnleeakrlgikkaitanismgaaflliyasyalafwygttlvlsgeysigqv
ltvffsvligafsvgqaspnieafanargaayevfkiidnkpsidsfsksghkpdniqgn
lefknihfsypsrkevqilkglnlkvksgqtvalvgnsgagksttvqlmqrlydpldgmv
sidgqdirtinvrylreiigvvsqepvlfattiaenirygredvtmdeiekavkeanayd
fimklphqfdtlvgergaqlsggqkqriaiaralvrnpkillldeatcaldteseavvqa
aldkaregrttiviahrlstvrnadviagfdggviveqgnhdelmrekgiyfklvmtqta
gneielgneaakskdeidnldmsskdsgsslirrrstrksiagphdqdrklstkealded
vppasfwrilklnstewpyfvvgifvaiingglqpafsvifskiigvftriddpetkrqn
snlfsllflilgiisfitfflqgftfgkageiltkrlrymvfksmlrqdvswfddpkntt
galttrlandaaqvkgatgsrlavifqnianlgtgiiisfiygwqltllllaivpiiaia
gvvemkmlsgqalkdkkelegsgkiateaienfrtvvsltreqkfetmyaqslqipyrna
mkkahvfgitfsftqammyfsyaaafrfgaylvahklmsfedvllvfsaivfgamavgqv
ssfapdyakatvsashiiriiektpeidsystqglkpnmlegnvqfsgvvfnyptrpsip
vlqglslevkkgqtlalvgssgagkstvvqllerfydpmagsvfldgkeikqlnvqwlra
qlgivsqepilfdtsiaeniaygdnsrvvsyeeivraakeanihqfidslpdkyntrvgd
kgtqlsggqkqriaiaralvrqphillldeatcaldtesekvvqealdkaregrttivia
hrlstiqnadlivviqngkvkehgthqqllaqkgiyfsmvsvqagakrs

    Sequence, based on observed residues (ATOM records):
    >6fn1A (A:)
pavsvltmfryagwldrlymlvgtlaaiihgvalplmmlifgemtdifanagnledlmsn
itnrsdindtgffmnleedmttyayyytgigagvlivayiqvsfwllaagrqihkirqkf
fhaimnqeigwfdvhdvgelntrltddvskinegigdkigmffqamatffggfiigftrg
wkltlvilaispvlglsagiwakilssftdkelhayakagavaeevlaairtviafggqk
kelerynnnleeakrlgikkaitanismgaaflliyasyalafwygttlvlsgeysigqv
ltvffsvligafsvgqaspnieafanargaayevfkiidnkpsidsfsksghkpdniqgn
lefknihfsypsrkevqilkglnlkvksgqtvalvgnsgagksttvqlmqrlydpldgmv
sidgqdirtinvrylreiigvvsqepvlfattiaenirygredvtmdeiekavkeanayd
fimklphqfdtlvgergaqlsggqkqriaiaralvrnpkillldeatcaldteseavvqa
aldkaregrttiviahrlstvrnadviagfdggviveqgnhdelmrekgiyfklvmtqtp
asfwrilklnstewpyfvvgifvaiingglqpafsvifskiigvftriddpetkrqnsnl
fsllflilgiisfitfflqgftfgkageiltkrlrymvfksmlrqdvswfddpknttgal
ttrlandaaqvkgatgsrlavifqnianlgtgiiisfiygwqltllllaivpiiaiagvv
emkmlsgqalkdkkelegsgkiateaienfrtvvsltreqkfetmyaqslqipyrnamkk
ahvfgitfsftqammyfsyaaafrfgaylvahklmsfedvllvfsaivfgamavgqvssf
apdyakatvsashiiriiektpeidsystqglkpnmlegnvqfsgvvfnyptrpsipvlq
glslevkkgqtlalvgssgagkstvvqllerfydpmagsvfldgkeikqlnvqwlraqlg
ivsqepilfdtsiaeniaygdnsrvvsyeeivraakeanihqfidslpdkyntrvgdkgt
qlsggqkqriaiaralvrqphillldeatcaldtesekvvqealdkaregrttiviahrl
stiqnadlivviqngkvkehgthqqllaqkgiyfsmvsvqag

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records:
    >6fn1B (B:)
qvvmtqsplslpvslgdqasiscrssqsllhsngntylhwylqkpgqspklliykvsnrf
sgvpdrfsgsgsgtdftlkisrveaedlgvyfcsqsthippwtfgggtkldikradaapt
vsifppsseqltsgglsvvcflnnfypkdinvkwkidgserqngvlnswtdqdskdstys
msstltltkdeyerhnsytceathktstspivksfnrnec

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records:
    >6fn1C (C:)
evqlqesgpelvktgasvkisckasgysfsnyyihwvkqshgkslewigfiscyngatfy
nqkfkgkatftvdnssstaymkfnsltfedsavyycarlpiqfgnfypmdywgqgttvtv
ssakttapsvyplapvcgdttgssvtlgclvkgyfpepvtltwnsgslssgvhtfpavlq
sdlytlsssvtvtsstwpsqsitcnvahpasstkvdkkieprgpt