PDB entry 6fhh

View 6fhh on RCSB PDB site
Description: crystal structure of bat influenza a/h17n10 polymerase with viral rna promoter bound to a 22-mer modified pol ii ctd peptide with serine 5 thiophosphorylated.
Deposited on 2018-01-14, released 2019-01-30
The last revision was dated 2019-01-30, with a file datestamp of 2019-01-25.
Experiment type: XRAY
Resolution: 2.7 Å
R-factor: N/A
AEROSPACI score: 0.18 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Polymerase acidic protein
    Species: Influenza A virus [TaxId:1129347]
    Gene: PA
    Database cross-references and differences (RAF-indexed):
    • Uniprot H6QM92 (14-726)
      • expression tag (727-737)
  • Chain 'B':
    Compound: RNA-directed RNA polymerase catalytic subunit
    Species: Influenza A virus [TaxId:1129347]
    Gene: Pb1
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Polymerase basic protein 2
    Species: Influenza A virus [TaxId:1129347]
    Gene: pb2
    Database cross-references and differences (RAF-indexed):
    • Uniprot H6QM90 (9-End)
      • expression tag (7-8)
  • Chain 'R':
    Compound: RNA (5'-r(*up*ap*up*ap*cp*cp*up*cp*up*gp*cp*up*u)-3')
    Species: Influenza A virus, synthetic [TaxId:11320]
  • Chain 'V':
    Compound: RNA (5'-r(p*ap*gp*up*ap*gp*up*ap*ap*cp*ap*ap*gp*ap*gp*gp*g)-3')
    Species: Influenza A virus, synthetic [TaxId:11320]
  • Chain 'X':
    Compound: tyr-ser-pro-thr-tps-pro-ser
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6FHH (0-End)
  • Chain 'Y':
    Compound: tyr-ser-pro-thr-tps-pro-ser
    Species: HOMO SAPIENS, synthetic [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • PDB 6FHH
  • Heterogens: PO4, ZN, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6fhhA (A:)
gshhhhhhhhgsgsmenfvrtnfnpmileraektmkeygenpqnegnkfaaisthmevcf
mysdfhfidlegntivkendddnamlkhrfeiiegqerniawtivnsicnmtenskprfl
pdlydyktnkfieigvtrrkvedyyyekasklkgenvyihifsfdgeematddeyildee
srariktrlfvlrqelataglwdsfrqsekgeetleeefsypptfqrlanqslppsfkdy
hqfkayvssfkangnieaklgamsekvnaqiesfdprtirelelpegkfctqrskfllmd
amklsvlnpahegegipmkdakacldtfwgwkkatiikkhekgvntnylmiweqllesik
emegkflnlkktnhlkwglgegqapekmdfedckevpdlfqykseppekrklaswiqsef
nkaseltnsnwiefdelgndvapiehiasrrrnfftaevsqcraseyimkavyintalln
ssctameeyqvipiitkcrdtsgqrrtnlygfiikgrshlrndtdvvnfislefsltdpr
neihkwekycvleigdmeirtsistimkpvylyvrtngtskikmkwgmemrrcllqslqq
vesmieaesavkekdmtepffrnrendwpigespqgiekgtigkvcrvllaksvfnsiya
saqlegfsaesrklllliqafrdnldpgtfdlkglyeaieeciindpwvllnaswfnsfl
kavqlsmgsgsgenlyfq

    Sequence, based on observed residues (ATOM records):
    >6fhhA (A:)
menfvrtnfnpmileraektmkeygenpqnegnkfaaisthmevcfmysdfhfidlegnt
ivkendddnamlkhrfeiiegqerniawtivnsicnmtenskprflpdlydyktnkfiei
gvtrrkvedyyyekasklkgenvyihifsfdgeematddeyildeesrariktrlfvlrq
elataleeefsypptfqrlanqslppsfkdyhqfkayvssfkangnieaklgamsekvna
qiesfdprtirelelpegkfctqrskfllmdamklsvlnpahegegipmkdakacldtfw
gwkkatiikkhekgvntnylmiweqllesikemegkflnlkktnhlkwglgegqapekmd
fedckevpdlfqykseppekrklaswiqsefnkaseltnsnwiefdelgndvapiehias
rrrnfftaevsqcraseyimkavyintallnssctameeyqvipiitkcrdtsgqrrtnl
ygfiikgrshlrndtdvvnfislefsltdprneihkwekycvleigdmeirtsistimkp
vylyvrtngtskikmkwgmemrrcllqslqqvesmieaesavkekdmtepffrnrendwp
igespqgiekgtigkvcrvllaksvfnsiyasaqlegfsaesrklllliqafrdnldpgt
fdlkglyeaieeciindpwvllnaswfnsflkavqlsmgsgsgenlyfq

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6fhhB (B:)
gsgsgsgsgmdvnpmliflkvpvqnaisttfpytgdppyshgtgtgytmdtvirthdyss
rgiwktnsetgaqqlnpidgplpednepsgyaqtdcvleliegldrshpglfetacqeti
daiqqtrvdkltqgrqtydwtlnrnqpaatalantievfrkngyklnesgrlidflkdvl
lsfendsmevtthfqkkkrirdnhskkmitqrtigkkrvkltkknyliraltlntmtkda
ergklkrraiatpgmqirgfvyfvellarnicerleqsglpvggnekkaklanvikkmma
kstdeelsytitgdntkwnenqnpriflamvlritagqpewfrdllavapimfsnkvarl
grgymfesksmhlrtqisaenlsdinlryfnedtkkkiekirhlmvegtaslspgmmmgm
fnmlstvlgvsvlnlgqreilkrtywwdglqssddfaliinghfkediqqgvnhfyrtck
lvginmsqkksyinktgtfeftsffyrygfvanfsmelpsfgvagnnesadmsigttvik
tnminndlgpataqmaiqlfikdyrytyrchrgdtnletrrtksikrlwtetiskagllv
adggpnpynlrnlhipevclkwslmdpdyrgrlcnpnnpfvhhmevestnlavvmpahgp
aksleydavatthswtpkrnrsilntnqrgilederiyqkccqvfekffpsstyrrpigm
asmldamlsraridaridlesgrissqdfseitntckaiealkrqgsgsgenlyfq

    Sequence, based on observed residues (ATOM records):
    >6fhhB (B:)
mdvnpmliflkvpvqnaisttfpytgdppyshgtgtgytmdtvirthdyssrgiwktnse
tgaqqlnpidgplpednepsgyaqtdcvleliegldrshpglfetacqetidaiqqtrvd
kltqgrqtydwtlnrnqpaatalantievfrkngyklnesgrlidflkdvllsfendsme
vtthfqkkkrirdnkkmitqrtigkkrvkltkknyliraltlntmtkdaergklkrraia
tpgmqirgfvyfvellarnicerleqsglpvggnekkaklanvikkmmakstdeelsyti
tgdntkwnenqnpriflamvlritagqpewfrdllavapimfsnkvarlgrgymfesksm
hlrtqisaenlsdinlryfnedtkkkiekirhlmvegtaslspgmmmgmfnmlstvlgvs
vlnlgqreilkrtywwdglqssddfaliinghfkediqqgvnhfyrtcklvginmsqkks
yinktgtfeftsffyrygfvanfsmelpsfgvagnnesadmsigttviktnminndlgpa
taqmaiqlfikdyrytyrchrgdtnletrrtksikrlwtetiskagllvadggpnpynlr
nlhipevclkwslmdpdyrgrlcnpnnpfvhhmevestnlavvmpgpaksleydavatth
swtpkrnrsilntnqrgilederiyqkccqvfekffpsstyrrpigmasmldamlsrari
daridlesgrissqdfseitntckaiealk

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6fhhC (C:)
gsgsgsgsgmerikelmemvknsrmreiltttsvdhmavikkytsgrqeknpalrmkwmm
amkypisassriremipekdedgntlwtntkdagsnrvlvspnavtwwnragpvsdvvhy
prvykmyfdrlerlthgtfgpvkfynqvkvrkrvdinpghkdltsreaqevimevvfpne
vgartlssdaqltitkekkeelknckispimvaymlerelvrrtrflpiagatsstyvev
lhltqgtcweqqytpggeaenddldqtliiasrnivrrsivaidplasllsmchttsiss
eplveilrsnptdeqavnickaalgirinnsfsfggynfkrvkgssqrtekavltgnlqt
ltmtifegyeefnvsgkrasavlkkgaqrliqaiiggrtledilnlmitlmvfsqeekml
kavrgdlnfvnranqrlnpmyqllrhfqkdsstllknwgteeidpimgiagimpdgtink
tqtlmgvrlsqggvdeysfnerirvnidkylrvrnekgellispeevseaqgqeklpiny
nsslmwevngpesiltntyhwiiknwellktqwmtdptvlynriefepfqtlipkgnrai
ysgftrtlfqqmrdvegtfdsiqiikllpfsahppslgrtqfssftlnirgaplrllirg
nsqvfnynqmenviivlgksvgspersiltesssiesavlrgflilgkanskygpvltig
eldklgrgekanvligqgdtvlvmkrkrdssiltdsqtalkrirleeskgwshpqfekgg
gsgggsggsawshpqfekgrsggenlyfq

    Sequence, based on observed residues (ATOM records):
    >6fhhC (C:)
sgmerikelmemvknsrmreiltttsvdhmavikkytsgrqeknpalrmkwmmamkypis
assriremipekdedgntlwtntkdagsnrvlvspnavtwwnragpvsdvvhyprvykmy
fdrlerlthgtfgpvkfynqvkvrkrvdinpghkdltsreaqevimevvfpnevgartls
sdaqltitkekkeelknckispimvaymlerelvrrtrflpiagatsstyvevlhltqgt
cweqqytpggeaenddldqtliiasrnivrrsivaidplasllsmchttsisseplveil
rsnptdeqavnickaalgirinnsfsfggynfkrvkgssqrtekavltgnlqtltmtife
gyeefnvsgkrasavlkkgaqrliqaiiggrtledilnlmitlmvfsqeekmlkavrgdl
nfnpmyqllrhfqkdsstllknwgteeidpimgiagimpdgtinktqtlmgvrlsqirvn
idkylrvrnekgellispeevseaqgqeklpinynsslmwevngpesiltntyhwiiknw
ellktqwmtdptvlynriefepfqtlipkgnraiysgftrtlfqqmrdvegtfdsiqiik
llpfsahppslgrtqfssftlnirgaplrllirgnsqvfnynqmenviivlgksvgsper
siltesssiesavlrgflilgkanskygpvltigeldklgrgekanvligqgdtvlvmkr
krdss

  • Chain 'R':
    No sequence available.

  • Chain 'V':
    No sequence available.

  • Chain 'X':
    Sequence, based on SEQRES records:
    >6fhhX (X:)
ysptxpsysptspsysptxpsy

    Sequence, based on observed residues (ATOM records):
    >6fhhX (X:)
ysptxps

  • Chain 'Y':
    Sequence, based on SEQRES records:
    >6fhhY (Y:)
ysptxpsysptxpsysptxpsy

    Sequence, based on observed residues (ATOM records):
    >6fhhY (Y:)
psysptxpsy