PDB entry 6fh5

View 6fh5 on RCSB PDB site
Description: PI3Kg IN COMPLEX WITH Compound 7
Class: transferase
Keywords: Kinase, inhibitor, complex, TRANSFERASE
Deposited on 2018-01-12, released 2019-01-30
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-01-30, with a file datestamp of 2019-01-25.
Experiment type: XRAY
Resolution: 2.84 Å
R-factor: N/A
AEROSPACI score: 0.15 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
    Species: Homo sapiens [TaxId:9606]
    Gene: PIK3CG
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fh5a1, d6fh5a2, d6fh5a3
  • Heterogens: DD8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fh5A (A:)
mseesqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwv
tskplpeylwkkianncifivihrsttsqtikvspddtpgailqsfftkmakkkslmdip
esqseqdfvlrvcgrdeylvgetpiknfqwvrhclkngeeihvvldtppdpaldevrkee
wplvddctgvtgyheqltihgkdhesvftvslwdcdrkfrvkirgidipvlprntdltvf
veaniqhgqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycgkapals
skasaespsseskgkvqllyyvnlllidhrfllrrgeyvlhmwqisgkgedqgsfnadkl
tsatnpdkensmsisilldnychpialpkhqptpdpegdrvraempnqlrkqleaiiatd
plnpltaedkellwhfryeslkhpkaypklfssvkwgqqeivaktyqllarrevwdqsal
dvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkfepyhdsalarfll
krglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtamlhdftqqvqvieml
qkvtldikslsaekydvssqvisqlkqklenlqnsqlpesfrvpydpglkagalaiekck
vmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlilqilrimesiwetesldl
cllpygcistgdkigmieivkdattiakiqqstvgntgafkdevlnhwlkekspteekfq
aaverfvyscagycvatfvlgigdrhndnimitetgnlfhidfghilgnyksflginker
vpfvltpdflfvmgtsgkktsphfqkfqdicvkaylalrhhtnlliilfsmmlmtgmpql
tskedieyirdaltvgkneedakkyfldqievcrdkgwtvqfnwflhlvlgikqgekhsa
hhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6fh5A (A:)
esqafqrqltaligydvtdvsnvhddeleftrrglvtprmaevasrdpklyamhpwvtsk
plpeylwkkianncifivihrttsqtikvspddtpgailqdfvlrvcgrdeylvgetpik
nfqwvrhclkngeeihvvldtppdpaldevrkvslwdcdrkfrvkirgidipvtvfvean
iqhgqqvlcqrrtspkpfteevlwnvwlefsikikdlpkgallnlqiycqllyyvnllli
dhrfllrrgeyvlhmwqisfnadkltsatnpdkensmsisilldnychpialpkraempn
qlrkqleaiiatdplnpltaedkellwhfryeslkhpkaypklfssvkwgqqeivaktyq
llarrevwdqsaldvgltmqlldcnfsdenvraiavqklesledddvlhyllqlvqavkf
epyhdsalarfllkrglrnkrighflfwflrseiaqsrhyqqrfavileaylrgcgtaml
hdftqqvqviemlqkvtldikslsassqvisqlkqklenlqnlpesfrvpydpglkagal
aiekckvmaskkkplwlefkcadptalsnetigiifkhgddlrqdmlilqilrimesiwe
tesldlcllpygcistgdkigmieivkdattiakiqqkdevlnhwlkekspteekfqaav
erfvyscagycvatfvlgigdrhndnimitetgnlfhidfghervpfvltpdflfvmgts
gtsphfqkfqdicvkaylalrhhtnlliilfsmmlmtgmkedieyirdaltvgkneedak
kyfldqievcrdkgwtvqfnwf