PDB entry 6fgc

View 6fgc on RCSB PDB site
Description: Crystal structure of Gephyrin E domain in complex with Artesunate
Class: structural protein
Keywords: Antimalarial compound, artemisinins and its derivatives, Inhibitory neurotransmission, Moco biosynthesis, STRUCTURAL PROTEIN
Deposited on 2018-01-10, released 2019-01-16
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-03-06, with a file datestamp of 2019-03-01.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: gephyrin
    Species: Rattus norvegicus [TaxId:10116]
    Gene: Gphn, Gph
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6fgca1, d6fgca2, d6fgca3
  • Heterogens: CA, ADP, PO4, MPD, MRD, ACT, D95, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6fgcA (A:)
mspfpltsmdkafitvlemtpvlgteiinyrdgmgrvlaqdvyakdnlppfpasvkdgya
vraadgpgdrfiigesqageqptqtvmpgqvmrvttgapipcgadavvqvedteliresd
dgteelevrilvqarpgqdirpighdikrgecvlakgthmgpseigllatvgvtevevnk
fpvvavmstgnellnpeddllpgkirdsnrstllatiqehgyptinlgivgdnpddllna
lnegisradviitsggvsmgekdylkqvldidlhaqihfgrvfmkpglpttfatldidgv
rkiifalpgnpvsavvtcnlfvvpalrkmqgildprptiikarlscdvkldprpeyhrci
ltwhhqeplpwaqstgnqmssrlmsmrsangllmlppkteqyvelhkgevvdvmvigrl

    Sequence, based on observed residues (ATOM records): (download) 
    >6fgcA (A:)
spfpltsmdkafitvlemtpvlgteiinyrdgmgrvlaqdvyakdnlppfpasvkdgyav
raadgpgdrfiigesqageqptqtvmpgqvmrvttgapipcgadavvqvedteliresdd
gteelevrilvqarpgqdirpighdikrgecvlakgthmgpseigllatvgvtevevnkf
pvvavmstgnellnpeddllpgkirdsnrstllatiqehgyptinlgivgdnpddllnal
negisradviitsggvsmgekdylkqvldidlhaqihfgrvfmkpglpttfatldidgvr
kiifalpgnpvsavvtcnlfvvpalrkmqgildprptiikarlscdvkldprpeyhrcil
twhhqeplpwaqstglmsmrsangllmlppkteqyvelhkgevvdvmvigrl