PDB entry 6ffy

View 6ffy on RCSB PDB site
Description: structure of the mouse sorcs2-ngf complex
Deposited on 2018-01-09, released 2018-08-01
The last revision was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 3.9 Å
R-factor: N/A
AEROSPACI score: 0.14 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: VPS10 domain-containing receptor SorCS2
    Species: Mus musculus [TaxId:10090]
    Gene: Sorcs2
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9EPR5
      • conflict (137)
  • Chain 'B':
    Compound: Beta-nerve growth factor
    Species: Mus musculus [TaxId:10090]
    Gene: Ngf, Ngfb
    Database cross-references and differences (RAF-indexed):
  • Chain 'C':
    Compound: Beta-nerve growth factor
    Species: Mus musculus [TaxId:10090]
    Gene: Ngf, Ngfb
    Database cross-references and differences (RAF-indexed):
  • Heterogens: NAG

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ffyA (A:)
    garavpvagaasasraqvslistsfvlkgdathnqamvhwtgenssvililtkyyhadmg
    kvlesslwrssdfgttytkltlqpgvttvidnfyicpankrkiilvssslgdreqslfls
    tdegatfqkypvpflvetllfhpkeedkvlaytkdsklyvssdlgkkwtllqervtkdhv
    fwavsgvdddpnlvhveaqdlsggyryytcliyncsaqphiapfsgpidrgsltvqdeyi
    flkatstnrtkyyvsyrrsdfvlmklpkyalpkdlqiistdeqqvfvavqewnqvdtynl
    yqsdlrgvryslvlenvrssrqaeenvvidilevrgvkgvflanqkvdgkvttvitynkg
    rdwdylrppstdmngkptncqppdcylhlhlrwadnpyvsgtvhtkdtapglimgagnlg
    sqlveykeemyitsdcghtwrqvfeeehhvlyldhggviaaikdtsiplkilkfsvdegh
    twsthnftstsvfvdgllsepgdetlvmtvfghisfrsdwelvkvdfrpsfprqcgeddy
    sswdltdlqgdhcimgqqrsyrkrkstswcvkgrsftsaltsrvckcrdsdflcdygfer
    ssssestankcsanfwfnplsppedcvlgqtytsslgyrkvvsnvceggvdlqqspvqlq
    cplqaprglqvsirgeavavrpredvlfvvrqeqgdvlttkyqvdlgdgfkamyvnltlt
    gepirhhyespgiyrvsvraenmaghdeavlfvqvnsplqalylevvpvigvnqevnlta
    vllplnpnltvfywwighslqpllsldnsvttkftdagdvrvtvqaacgnsvlqdsrlvr
    vldqfqvvplrfsreldtfnpntpewredvglvvtrllsketsipeellvtvvkpglpti
    adlyvllplprptrkrsltsdkrlaavqqalnshrisfilrgglrilvelrdtdtgpqrp
    ggsaaahhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >6ffyA (A:)
    qvslistsfvlkgdathnqamvhwtgenssvililtkyyhadmgkvlesslwrssdfgtt
    ytkltlqpgvttvidnfyicpakiilvssslgdreqslflstdegatfqkypvpflvetl
    lfhpkeedkvlaytkdsklyvssdlgkkwtllqervtkdhvfwavsgvdddpnlvhveaq
    dlsggyryytcliynchiapfsgpidrgsltvqdeyiflkatstnrtkyyvsyrrsdfvl
    mklpkyalpkdlqiistdeqqvfvavqewnqvdtynlyqsdlrgvryslvlenvrssrqa
    eenvvidilevrgvkgvflanqkvdgkvttvitynkgrdwdylrppstdmngkptncqpp
    dcylhlhlrwadnpyvsgtvhtkdtapglimgagnlgsqlveykeemyitsdcghtwrqv
    feeehhvlyldhggviaaikdtsiplkilkfsvdeghtwsthnftstsvfvdgllsepgd
    etlvmtvfghisfrsdwelvkvdfrpsfprqcgeddysswdltdlqgdhcimgqqrsyrk
    rkstswcvkgrsftsaltsrvckcrdsdflcdygferssssestankcsanfwfnplspp
    edcvlgqtytsslgyrkvvsnvceggvdlqqspvqlqcplqaprglqvsirgeavavrpr
    edvlfvvrqeqgdvlttkyqvdlgdgfkamyvnltltgepirhhyespgiyrvsvraenm
    aghdeavlfvqvnsplqalylevvpvigvnqevnltavllnpnltvfywwighslqplls
    ldnsvttkftdagdvrvtvqaacgnsvlqdsrlvrvldqfqvvplrfsreldtfnpntpe
    wredvglvvtrllsketsipeellvtvvkpglptiadlyvllpltsdkrlaavqqalnsh
    risfilrgglrilvelrd
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ffyB (B:)
    ssthpvfhmgefsvcdsvsvwvgdkttatdikgkevtvlaevninnsvfrqyffetkcra
    snpvesgcrgidskhwnsycttthtfvkalttdekqaawrfiridtacvcvlsrkataag
    aaahhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >6ffyB (B:)
    hmgefsvcdsvsvwvgdkttatdikgkevtvlaevninnsvfrqyffetkcrasnpvesg
    crgidskhwnsycttthtfvkalttdekqaawrfiridtacvcvlsrkat
    

  • Chain 'C':
    Sequence, based on SEQRES records:
    >6ffyC (C:)
    ssthpvfhmgefsvcdsvsvwvgdkttatdikgkevtvlaevninnsvfrqyffetkcra
    snpvesgcrgidskhwnsycttthtfvkalttdekqaawrfiridtacvcvlsrkataag
    aaahhhhhh
    

    Sequence, based on observed residues (ATOM records):
    >6ffyC (C:)
    fhmgefsvcdsvsvwvgdkttatdikgkevtvlaevninnsvfrqyffetkcrasnpves
    gcrgidskhwnsycttthtfvkalttdekqaawrfiridtacvcvlsrkat