PDB entry 6ffi

View 6ffi on RCSB PDB site
Description: crystal structure of mglur5 in complex with mmpep at 2.2 a
Deposited on 2018-01-08, released 2018-03-07
The last revision was dated 2019-04-24, with a file datestamp of 2019-04-19.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Metabotropic glutamate receptor 5,Endolysin,Metabotropic glutamate receptor 5
    Species: Homo sapiens [TaxId:9606]
    Gene: GRM5, GPRC1E, MGLUR5
    Database cross-references and differences (RAF-indexed):
    • Uniprot P41594 (3-112)
      • expression tag (2)
      • engineered mutation (13)
      • engineered mutation (101)
      • engineered mutation (103)
      • engineered mutation (109)
    • Uniprot P00720 (113-273)
      • conflict (123)
      • conflict (165)
      • conflict (208)
      • conflict (248)
    • Uniprot P41594 (274-End)
      • engineered mutation (336)
      • engineered mutation (347)
  • Heterogens: OLA, MES, D8B, HOH

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ffiA (A:)
aaspvqylrwgdpapiaavvfaclgllatlfvtvvfiiyrdtpvvksssrelcyiilagi
clgylctfcliakpkqiycylqrigiglspamsysalvtktyraarilamskknifemlr
ideglrlkiykdtegyytigighlltkspslnaakseldkaigrntngvitkdeaeklfn
qdvdaavrgilrnaklkpvydsldavrraalinmvfqmgetgvagftnslrmlqqkrwde
aavnlaksrwynqtpnrakrvittfrtgtwdaykictkkprfmsacaqlviafiliciql
giivalfimeppdimhdypsirevylicnttnlgvvaplgyngllilactfyafktrnvp
anfneakyiaftmyttciiwlafvpiyfgsnykiitmcfsvslsatvalgcmfvpkvyii
lakpernvrsaaaahhhhhhhhhh

    Sequence, based on observed residues (ATOM records):
    >6ffiA (A:)
spvqylrwgdpapiaavvfaclgllatlfvtvvfiiyrdtpvvksssrelcyiilagicl
gylctfcliakpkqiycylqrigiglspamsysalvtktyraarilamskknifemlrid
eglrlkiykdtegyytigighlltkspslnaakseldkaigrntngvitkdeaeklfnqd
vdaavrgilrnaklkpvydsldavrraalinmvfqmgetgvagftnslrmlqqkrwdeaa
vnlaksrwynqtpnrakrvittfrtgtwdaykisacaqlviafiliciqlgiivalfime
ppdimevylicnttnlgvvaplgyngllilactfyafktrnvpanfneakyiaftmyttc
iiwlafvpiyfgsnykiitmcfsvslsatvalgcmfvpkvyiilakpern