PDB entry 6ffc

View 6ffc on RCSB PDB site
Description: structure of an inhibitor-bound abc transporter
Deposited on 2018-01-06, released 2018-04-11
The last revision was dated 2019-12-11, with a file datestamp of 2019-12-06.
Experiment type: EM
Resolution: 3.56 Å
R-factor: N/A
AEROSPACI score: 0.1 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ATP-binding cassette sub-family G member 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ABCG2, ABCP, BCRP, BCRP1, MXR
    Database cross-references and differences (RAF-indexed):
  • Chain 'B':
    Compound: ATP-binding cassette sub-family G member 2
    Species: Homo sapiens [TaxId:9606]
    Gene: ABCG2, ABCP, BCRP, BCRP1, MXR
    Database cross-references and differences (RAF-indexed):
  • Heterogens: BWQ

PDB Chain Sequences:
This PDB entry is not classified in SCOPe 2.08, so the chain sequences below are not included in the ASTRAL sequence sets.

  • Chain 'A':
    Sequence, based on SEQRES records:
    >6ffcA (A:)
    dykddddkgssssnvevfipvsqgntngfpatasndlkaftegavlsfhnicyrvklksg
    flpcrkpvekeilsningimkpglnailgptgggksslldvlaarkdpsglsgdvlinga
    prpanfkcnsgyvvqddvvmgtltvrenlqfsaalrlattmtnheknerinrviqelgld
    kvadskvgtqfirgvsggerkrtsigmelitdpsilfldepttgldsstanavllllkrm
    skqgrtiifsihqprysifklfdsltllasgrlmfhgpaqealgyfesagyhceaynnpa
    dffldiingdstavalnreedfkateiiepskqdkplieklaeiyvnssfyketkaelhq
    lsggekkkkitvfkeisyttsfchqlrwvskrsfknllgnpqasiaqiivtvvlglviga
    iyfglkndstgiqnragvlfflttnqcfssvsavelfvvekklfiheyisgyyrvssyfl
    gkllsdllpmrmlpsiiftcivyfmlglkpkadaffvmmftlmmvaysassmalaiaagq
    svvsvatllmticfvfmmifsgllvnlttiaswlswlqyfsiprygftalqhneflgqnf
    cpglnatgnnpcnyatctgeeylvkqgidlspwglwknhvalacmivifltiaylkllfl
    kkys
    

    Sequence, based on observed residues (ATOM records):
    >6ffcA (A:)
    gavlsfhnicyrvklpvekeilsningimkpglnailgptgggksslldvlaarkdpsgl
    sgdvlingaprpanfkcnsgyvvqddvvmgtltvrenlqfsaalrlattmtnheknerin
    rviqelgldkvadskvgtqfirgvsggerkrtsigmelitdpsilfldepttgldsstan
    avllllkrmskqgrtiifsihqprysifklfdsltllasgrlmfhgpaqealgyfesagy
    hceaynnpadffldiingdlieklaeiyvnssfyketkaelhqlsgyttsfchqlrwvsk
    rsfknllgnpqasiaqiivtvvlglvigaiyfglkndstgiqnragvlfflttnqcfssv
    savelfvvekklfiheyisgyyrvssyflgkllsdllpmrmlpsiiftcivyfmlglkpk
    adaffvmmftlmmvaysassmalaiaagqsvvsvatllmticfvfmmifsgllvnlttia
    swlswlqyfsiprygftalqhneflgqnfcpglnatgnnpcnyatctgeeylvkqgidls
    pwglwknhvalacmivifltiaylkllflkky
    

  • Chain 'B':
    Sequence, based on SEQRES records:
    >6ffcB (B:)
    dykddddkgssssnvevfipvsqgntngfpatasndlkaftegavlsfhnicyrvklksg
    flpcrkpvekeilsningimkpglnailgptgggksslldvlaarkdpsglsgdvlinga
    prpanfkcnsgyvvqddvvmgtltvrenlqfsaalrlattmtnheknerinrviqelgld
    kvadskvgtqfirgvsggerkrtsigmelitdpsilfldepttgldsstanavllllkrm
    skqgrtiifsihqprysifklfdsltllasgrlmfhgpaqealgyfesagyhceaynnpa
    dffldiingdstavalnreedfkateiiepskqdkplieklaeiyvnssfyketkaelhq
    lsggekkkkitvfkeisyttsfchqlrwvskrsfknllgnpqasiaqiivtvvlglviga
    iyfglkndstgiqnragvlfflttnqcfssvsavelfvvekklfiheyisgyyrvssyfl
    gkllsdllpmrmlpsiiftcivyfmlglkpkadaffvmmftlmmvaysassmalaiaagq
    svvsvatllmticfvfmmifsgllvnlttiaswlswlqyfsiprygftalqhneflgqnf
    cpglnatgnnpcnyatctgeeylvkqgidlspwglwknhvalacmivifltiaylkllfl
    kkys
    

    Sequence, based on observed residues (ATOM records):
    >6ffcB (B:)
    gavlsfhnicyrvklpvekeilsningimkpglnailgptgggksslldvlaarkdpsgl
    sgdvlingaprpanfkcnsgyvvqddvvmgtltvrenlqfsaalrlattmtnheknerin
    rviqelgldkvadskvgtqfirgvsggerkrtsigmelitdpsilfldepttgldsstan
    avllllkrmskqgrtiifsihqprysifklfdsltllasgrlmfhgpaqealgyfesagy
    hceaynnpadffldiingdlieklaeiyvnssfyketkaelhqlsgyttsfchqlrwvsk
    rsfknllgnpqasiaqiivtvvlglvigaiyfglkndstgiqnragvlfflttnqcfssv
    savelfvvekklfiheyisgyyrvssyflgkllsdllpmrmlpsiiftcivyfmlglkpk
    adaffvmmftlmmvaysassmalaiaagqsvvsvatllmticfvfmmifsgllvnlttia
    swlswlqyfsiprygftalqhneflgqnfcpglnatgnnpcnyatctgeeylvkqgidls
    pwglwknhvalacmivifltiaylkllflkky