PDB entry 6fe1

View 6fe1 on RCSB PDB site
Description: Three dimensional structure of human carbonic anhydrase IX in complex with benzenesulfonamide.
Class: lyase
Keywords: lyase
Deposited on 2017-12-28, released 2018-07-04
The last revision prior to the SCOPe 2.07 freeze date was dated 2018-07-04, with a file datestamp of 2018-06-29.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Carbonic anhydrase 9
    Species: Homo sapiens [TaxId:9606]
    Gene: CA9, G250, MN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16790 (Start-256)
      • engineered mutation (39)
    Domains in SCOPe 2.07: d6fe1a_
  • Chain 'B':
    Compound: Carbonic anhydrase 9
    Species: Homo sapiens [TaxId:9606]
    Gene: CA9, G250, MN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16790 (Start-256)
      • engineered mutation (39)
    Domains in SCOPe 2.07: d6fe1b_
  • Chain 'C':
    Compound: Carbonic anhydrase 9
    Species: Homo sapiens [TaxId:9606]
    Gene: CA9, G250, MN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16790 (Start-256)
      • engineered mutation (39)
    Domains in SCOPe 2.07: d6fe1c_
  • Chain 'D':
    Compound: Carbonic anhydrase 9
    Species: Homo sapiens [TaxId:9606]
    Gene: CA9, G250, MN
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q16790 (Start-256)
      • engineered mutation (39)
    Domains in SCOPe 2.07: d6fe1d_
  • Heterogens: V14, ZN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >6fe1A (A:)
    gpdqshwryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelr
    lrnnghsvqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvh
    lstafarvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldis
    allpsdfsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqln
    fratqplngrvieasfp
    

    Sequence, based on observed residues (ATOM records): (download)
    >6fe1A (A:)
    wryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelrlrnngh
    svqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvhlstafa
    rvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldisallpsd
    fsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqlnfratqp
    lngrvieasfp
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >6fe1B (B:)
    gpdqshwryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelr
    lrnnghsvqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvh
    lstafarvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldis
    allpsdfsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqln
    fratqplngrvieasfp
    

    Sequence, based on observed residues (ATOM records): (download)
    >6fe1B (B:)
    wprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelrlrnnghsvqltlpp
    glemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvhlstafarvdealgr
    pgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldisallpsdfsryfqye
    gslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqlnfratqplngrviea
    sfp
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >6fe1C (C:)
    gpdqshwryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelr
    lrnnghsvqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvh
    lstafarvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldis
    allpsdfsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqln
    fratqplngrvieasfp
    

    Sequence, based on observed residues (ATOM records): (download)
    >6fe1C (C:)
    wryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelrlrnngh
    svqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvhlstafa
    rvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldisallpsd
    fsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqlnfratqp
    lngrvieasfp
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >6fe1D (D:)
    gpdqshwryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelr
    lrnnghsvqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvh
    lstafarvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldis
    allpsdfsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqln
    fratqplngrvieasfp
    

    Sequence, based on observed residues (ATOM records): (download)
    >6fe1D (D:)
    wryggdppwprvspacagrfqspvdirpqlaafspalrplellgfqlpplpelrlrnngh
    svqltlppglemalgpgreyralqlhlhwgaagrpgsehtveghrfpaeihvvhlstafa
    rvdealgrpgglavlaafleegpeensayeqllsrleeiaeegsetqvpgldisallpsd
    fsryfqyegslttppcaqgviwtvfnqtvmlsakqlhtlsdtlwgpgdsrlqlnfratqp
    lngrvieasfp