PDB entry 6fd5
View 6fd5 on RCSB PDB site
Description: Crystal Structure of Human APRT-Tyr105Phe variant in complex with Adenine, PRPP and Mg2+, 14 days post crystallization (with AMP and PPi products partially generated)
Class: transferase
Keywords: rossman fold, transferase
Deposited on
2017-12-21, released
2018-08-15
The last revision prior to the SCOPe 2.08 freeze date was dated
2020-07-29, with a file datestamp of
2020-06-29.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: N/A
AEROSPACI score: 0.55
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Adenine phosphoribosyltransferase
Species: Homo sapiens [TaxId:9606]
Gene: APRT
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6fd5a_ - Chain 'B':
Compound: Adenine phosphoribosyltransferase
Species: Homo sapiens [TaxId:9606]
Gene: APRT
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d6fd5b_ - Heterogens: AMP, PPV, MG, GOL, PRP, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>6fd5A (A:)
dselqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridyia
gldsrgflfgpslaqelglgcvlirkrgklpgptlwasyslefgkaeleiqkdalepgqr
vvvvddllatggtmnaacellgrlqaevlecvslveltslkgreklapvpffsllqye
Sequence, based on observed residues (ATOM records): (download)
>6fd5A (A:)
dselqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridyia
gldsrgflfgpslaqelglgcvlirkrgklpgptlwasysaeleiqkdalepgqrvvvvd
dllatggtmnaacellgrlqaevlecvslveltslkgreklapvpffsllqye
- Chain 'B':
Sequence, based on SEQRES records: (download)
>6fd5B (B:)
dselqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridyia
gldsrgflfgpslaqelglgcvlirkrgklpgptlwasyslefgkaeleiqkdalepgqr
vvvvddllatggtmnaacellgrlqaevlecvslveltslkgreklapvpffsllqye
Sequence, based on observed residues (ATOM records): (download)
>6fd5B (B:)
selqlveqrirsfpdfptpgvvfrdispvlkdpasfraaigllarhlkathggridyiag
ldsrgflfgpslaqelglgcvlirkrgklpgptlwasyaeleiqkdalepgqrvvvvddl
latggtmnaacellgrlqaevlecvslveltslkgreklapvpffsllqye